Zobrazeno 1 - 7
of 7
pro vyhledávání: '"W. Clark Bacon"'
Autor:
Timothy C. Wang, Misty Troutt, W. Clark Bacon, Michael A. Helmrath, Joyce C. Niland, Magdalena Kasendra, Taylor Broda
Publikováno v:
Am J Physiol Gastrointest Liver Physiol
Recent advances in intestinal organoid research, along with encouraging preclinical proof-of-concept studies, have revealed significant therapeutic potential for induced pluripotent stem cell (iPSC)-derived organoids in the healing and replacement of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2887e03144b3c2bc46b0e50138572d15
https://doi.org/10.1152/ajpgi.00425.2020
https://doi.org/10.1152/ajpgi.00425.2020
Autor:
Hanna Osinska, Ellen Orthey, Jeffery D. Molkentin, Saskia Schlossarek, Jeffrey Robbins, Erda Alizoti, Sonia R. Singh, James Gulick, W. Clark Bacon, Moritz Meyer-Jens, Lucie Carrier, Gregory Davis, Silke Reischmann-Düsener, Patrick M. McLendon
Publikováno v:
Autophagy
article-version (VoR) Version of Record
article-version (VoR) Version of Record
The ubiquitin-proteasome system (UPS) and autophagy-lysosomal pathway (ALP) are two major protein degradation pathways in eukaryotic cells. Initially considered as two independent pathways, there is emerging evidence that they can work in concert. As
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2616168058768ad85f2eec8958db534
https://pubmed.ncbi.nlm.nih.gov/33249983
https://pubmed.ncbi.nlm.nih.gov/33249983
Autor:
Davis-Rodriguez Stephanie R, Zachary M. Thomas, Prasad Devarajan, Valeria Rudomanova, W. Clark Bacon, Stephanie L. K. Bowers, Burns C. Blaxall, Alex Beiersdorfer, Qing Ma
Publikováno v:
Am J Physiol Renal Physiol
Fibrosis is a common feature of chronic kidney disease; however, no clinical therapies effectively target the progression of fibrosis. Inhibition of fibronectin polymerization with the small peptide pUR4 attenuates fibrosis in the liver and heart. He
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba5d76f1c693c50b7ba8af8a7e097ee
https://europepmc.org/articles/PMC6620592/
https://europepmc.org/articles/PMC6620592/
Autor:
Patricia C. Fulkerson, Kaila L. Schollaert, Carine Bouffi, Andrey V. Kartashov, Xiaoting Chen, Matthew T. Weirauch, W. Clark Bacon, Artem Barski
Publikováno v:
The Journal of Immunology. 195:2683-2695
The production of mature eosinophils is a tightly orchestrated process with the aim to sustain normal eosinophil levels in tissues while also maintaining low numbers of these complex and sensitive cells in the blood. To identify regulators of homeost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55379604eeee6d4801907bc119b3009e
https://doi.org/10.4049/jimmunol.1500510
https://doi.org/10.4049/jimmunol.1500510
Autor:
Kenneth D. Greis, Andrey V. Kartashov, Satoshi H. Namekawa, Fan Zhang, So Maezawa, Yosuke Ichijima, Kazuteru Hasegawa, Tyler J. Broering, Ho-Su Sin, Paul R. Andreassen, Artem Barski, Kris G. Alavattam, W. Clark Bacon
Publikováno v:
Developmental cell, vol 32, iss 5
SummaryGametogenesis is dependent on the expression of germline-specific genes. However, it remains unknown how the germline epigenome is distinctly established from that of somatic lineages. Here we show that genes commonly expressed in somatic line
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ab0bde33dd6ece78a2747414fa134f
Autor:
W. Clark Bacon, Timothy J. Stephens, Jarrod Fortwendel, David S. Askew, Kevin K. Fuller, Judith C. Rhodes
Publikováno v:
Eukaryotic Cell. 7:1530-1539
The Ras family of proteins is a large group of monomeric GTPases. Members of the fungal Ras family act as molecular switches that transduce signals from the outside of the cell to signaling cascades inside the cell. A. fumigatus RasA is 94% identical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8020fc77ff2efd6c134b2c41a778d714
https://doi.org/10.1128/ec.00080-08
https://doi.org/10.1128/ec.00080-08
Publikováno v:
Cancer research. 64(8)
Neurofibromatosis type 2 (NF2) is a genetic disorder characterized by bilateral schwannomas of the eighth cranial nerve. The NF2 tumor suppressor protein, merlin, is related to the ERM (ezrin, radixin, and moesin) family of membrane/F-actin linkers.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2305abaaf61b3acfabc83c7af489890
https://pubmed.ncbi.nlm.nih.gov/15087385
https://pubmed.ncbi.nlm.nih.gov/15087385