Zobrazeno 1 - 10 of 307 pro vyhledávání: '"W. Charlton"'
1
Akademický článek
Convalescent human plasma candidate reference materials protect against Crimean-Congo haemorrhagic fever virus (CCHFV) challenge in an A129 mouse model
Autor: Sarah Kempster, Mark Hassall, Victoria Graham, Emma Kennedy, Stephen Findlay-Wilson, Francisco J. Salguero, Binnur Bagci, Nazif Elaldi, Murtaza Oz, Tuba Tasseten, Frank W. Charlton, John N. Barr, Juan Fontana, Chinwe Duru, Ernest Ezeajughi, Paul Matejtschuk, Ulrike Arnold, Yemisi Adedeji, Ali Mirazimi, Roger Hewson, Stuart Dowall, Neil Almond
Publikováno v: Virus Research, Vol 346, Iss , Pp 199409- (2024)
Crimean-Congo Haemorrhagic Fever Virus (CCHFV) is spread by infected ticks or direct contact with blood, tissues and fluids from infected patients or livestock. Infection with CCHFV causes severe haemorrhagic fever in humans which is fatal in up to 8
Externí odkaz: https://doaj.org/article/66708ffdc86a453d98aea18c1ee3b92c
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2
Akademický článek
Organisation of the orthobunyavirus tripodal spike and the structural changes induced by low pH and K+ during entry
Autor: Samantha Hover, Frank W. Charlton, Jan Hellert, Jessica J. Swanson, Jamel Mankouri, John N. Barr, Juan Fontana
Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Following endocytosis, enveloped viruses employ the changing environment of maturing endosomes as cues to promote endosomal escape, a process often mediated by viral glycoproteins. We previously showed that both high [K+] and low pH promote
Externí odkaz: https://doaj.org/article/89f71ba3dc2a4843a816c001509db607
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3
Akademický článek
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4
Akademický článek
Ion Channels as Therapeutic Targets for Viral Infections: Further Discoveries and Future Perspectives
Autor: Frank W. Charlton, Hayley M. Pearson, Samantha Hover, Jon D. Lippiat, Juan Fontana, John N. Barr, Jamel Mankouri
Publikováno v: Viruses, Vol 12, Iss 8, p 844 (2020)
Ion channels play key roles in almost all facets of cellular physiology and have emerged as key host cell factors for a multitude of viral infections. A catalogue of ion channel-blocking drugs have been shown to possess antiviral activity, some of wh
Externí odkaz: https://doaj.org/article/e7a4812d957f42fca080e4a7bce92b38
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5
Rangers can't be with every elephant: assessing rangers' perceptions of a community, problem-solving policing model for protected areas
Autor: William D. Moreto, Richard W. Charlton
Publikováno v: Oryx. 55:89-98
Recent studies have highlighted that illegal activities occurring within protected areas, including the poaching of fauna and flora, cannot be addressed with increased law enforcement alone. Moreover, research on the increasingly militarized nature o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31bb7d088e4771350c445668b017242f
https://doi.org/10.1017/s0030605318001461
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6
Cellular cholesterol abundance regulates potassium accumulation within endosomes and is an important determinant in bunyavirus entry
Autor: Jack Fuller, Juan Fontana, Jamel Mankouri, Frank W. Charlton, Roger Hewson, Samantha Hover, John N. Barr
Publikováno v: J Biol Chem
The Bunyavirales order of segmented negative sense RNA viruses includes over 500 isolates that infect insects, animals, and plants, and are often associated with severe and fatal disease in humans. To multiply and cause disease, bunyaviruses must tra
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c4d3cd0bac25dd6302d77634c20facb
https://doi.org/10.1074/jbc.ra119.007618
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7
The Convergence of CAPTURED Fish and People: Examining the Symbiotic Nature of Labor Trafficking and Illegal, Unreported and Unregulated Fishing
Autor: Samuel E. DeWitt, Richard W. Charlton, Christina Burton, William D. Moreto
Publikováno v: Deviant Behavior. 41:733-749
Environment crime has received considerable attention from criminologists in recent years. Not only have scholars examined the social, political, cultural, and situational factors that influence en...
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e610393e82160a2579ebe7812fe3955
https://doi.org/10.1080/01639625.2019.1594587
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8
Ion Channels as Therapeutic Targets for Viral Infections: Further Discoveries and Future Perspectives
Autor: Jon D. Lippiat, Hayley Pearson, Jamel Mankouri, John N. Barr, Samantha Hover, Juan Fontana, Frank W. Charlton
Publikováno v: Viruses, Vol 12, Iss 844, p 844 (2020)
Viruses
Ion channels play key roles in almost all facets of cellular physiology and have emerged as key host cell factors for a multitude of viral infections. A catalogue of ion channel-blocking drugs have been shown to possess antiviral activity, some of wh
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d02e6744ceb93a058097aa64bb4432b6
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10
Akademický článek
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