Zobrazeno 1 - 10
of 30
pro vyhledávání: '"W. C. Mahoney"'
Publikováno v:
Cytometry. 45(4)
We have developed a method for selecting erythroblasts from blood, the first step toward identifying fetal cells in maternal blood for diagnostic purposes. Because the selection method results in a large number of positive cells, we needed to develop
Autor:
E J, Collarini, C A, Cain, D, Gammon, B, Harriman, K, Magee, G, Du, P A, Schueler, W C, Mahoney
Publikováno v:
Cytometry. 45(4)
Many methods have been employed to obtain fetal cells from maternal blood for prenatal diagnostics, but there has been little work done that compares the efficacy of different methods. This study presents a comparison of two commonly used methods for
Publikováno v:
Biochemistry. 20:443-448
o-Iodoxybenzoic acid, a disproportionation product of o-iodosobenzoic acid, has been identified as a contaminant in most preparations of o-iodosobenzoic acid capable of both modifying and cleaving certain tyrosyl residues. A new synthetic approach fo
Autor:
W C Mahoney, D Duksin
Publikováno v:
Journal of Biological Chemistry. 254:6572-6576
Tunicamycin, an antibiotic that inhibits the transfer of N-acetyglucosamine-1-phosphate from UDP-N-acetylglucosamine to dolichol monophosphate and thereby blocks the formation of protein-carbohydrate linkages of the N-glycosidic type, is not a single
Publikováno v:
Journal of Biological Chemistry. 259:8412-8416
The amino acid sequence of a corn inhibitor for trypsin and activated Hageman Factor (Factor XIIa) was determined by automated Edman degradation from the intact inhibitor and two fragments generated by specific cleavage of the inhibitor. The 112-resi
Publikováno v:
Journal of Biological Chemistry. 258:9166-9174
The complete amino acid sequence of rabbit muscle phosphoglucomutase has been determined by isolating the 11 peptide fragments produced by the cyanogen bromide cleavage reaction and subjecting these to automated sequencing procedures. Products produc
Autor:
W C Mahoney, J W Orf
Publikováno v:
Clinical Chemistry. 31:459-462
The immunosuppressive drug cyclosporin A, has been successfully iodinated to a specific activity of 300 Ci per gram. 125I-labeled cyclosporin and [3H]cyclosporin are nearly equivalent as tracers in a radioimmunoassay in producing standard lines (supp
Publikováno v:
Journal of Biological Chemistry. 259:2870-2874
As a first step in studying the biosynthesis of the peptide hormone calcitonin, we have identified procalcitonin species in CA-77 cells, a newly developed rat medullary thyroid carcinoma cell line. mRNA extracted from the cells directed the synthesis
Autor:
H Zalkin, J M Groarke, W C Mahoney, Mark A. Hermodson, Clement E. Furlong, J N Hope, Frank T. Robb
Publikováno v:
Journal of Biological Chemistry. 258:12952-12956
The amino acid sequence of the D-ribose-binding protein from Escherichia coli K12 was determined from the DNA sequence of the gene. Protein sequence analyses covering 80% of the protein were consistent with the sequence deduced from the DNA. The matu
Publikováno v:
Journal of Biological Chemistry. 257:10978-10985
The entire amino acid sequence of hypoxanthine-guanine phosphoribosyltransferase from human erythrocytes has been defined. Peptide fragments formed by cleavage at arginine, glutamic acid, and methionine residues were analyzed by Edman degradation or