Zobrazeno 1 - 10
of 98
pro vyhledávání: '"W. C. Hunt"'
Publikováno v:
Paediatrics Publications
Tissue Barriers
Tissue Barriers
Chronic inflammatory skin disorders are frequently associated with impaired skin barrier function. Selective phosphodiesterase-4 (PDE4) inhibition constitutes an effective therapeutic strategy for the treatment of inflammatory skin diseases. We now r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b2bc573b5bbe78e64a1c09b3c075f4e
https://ir.lib.uwo.ca/context/paedpub/article/2035/viewcontent/17.247.pdf
https://ir.lib.uwo.ca/context/paedpub/article/2035/viewcontent/17.247.pdf
Publikováno v:
Photochemistry and Photobiology. 76:224-231
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38c013ff6071615308019b9005597ca1
https://doi.org/10.1562/0031-8655(2002)0760224saotpq2.0.co2
https://doi.org/10.1562/0031-8655(2002)0760224saotpq2.0.co2
Autor:
B.A. Cassidy, Bruce M. McManus, David J. Granville, C. van Breemen, Dietrich O. Ruehlmann, Jonathan C. Choy, David W. C. Hunt
Publikováno v:
Cell Calcium. 30:343-350
Photodynamic therapy (PDT) is clinically approved for the treatment of several types of cancer as well as age-related macular degeneration, the leading cause of blindness in the elderly. PDT using the photosensitizer verteporfin has been previously s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d8951b65ed30fb490ee0cbf95b8cbf
https://doi.org/10.1054/ceca.2001.0243
https://doi.org/10.1054/ceca.2001.0243
Publikováno v:
Journal of Molecular and Cellular Cardiology. 33:1673-1690
The high turnover of endothelial cells (EC) in atherosclerosis suggests that an increase in the frequency of both cell proliferation and cell death is important in the pathogenesis of this common disorder. Further, increased apoptosis of EC, smooth m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37d3774bd22791228bbebc89d3b0b248
https://doi.org/10.1006/jmcc.2001.1419
https://doi.org/10.1006/jmcc.2001.1419
Publikováno v:
International Immunopharmacology. 1:1831-1840
Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) and Fas ligand (FasL) trigger apoptosis by stimulating the formation of a death inducing signaling complex at the cytoplasmic terminus of their respective receptors. Photodynamic therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::533fabd68737977d473dba239dc3863c
https://doi.org/10.1016/s1567-5769(01)00107-2
https://doi.org/10.1016/s1567-5769(01)00107-2
Autor:
Dietrich O. Ruehlmann, Catherine Brenner, Philippe Margaron, David J. Granville, Jonathan C. Choy, Bruce M. McManus, Cornelis van Breemen, Brighid A. Cassidy, David W. C. Hunt, Guido Kroemer
Publikováno v:
The American Journal of Pathology. 159:305-311
Photodynamic therapy (PDT) is under investigation for the treatment of intimal hyperplastia in conditions such as atherosclerosis and restenosis. Although smooth muscle cells (SMCs) may be a key target for treatment, the effects of PDT on these cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5a9285fae25f2c5f5a57dee98e939bd
https://doi.org/10.1016/s0002-9440(10)61696-3
https://doi.org/10.1016/s0002-9440(10)61696-3
Autor:
Christopher M. Carthy, Laurie P. Peiffer, Thomas J. McGarrity, David J. Granville, David W. C. Hunt, Mukul Khandelwal, Julia G. Levy
Publikováno v:
Cancer Letters. 163:33-41
Tumor cell death in vitro by photodynamic therapy (PDT) has been related to the induction of apoptosis. We measured and compared changes in apoptosis and caspase 3 activity, an effector of apoptosis, in normal and neoplastic esophageal tissues during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f73b9e12882daa5834225987a6717578
https://doi.org/10.1016/s0304-3835(00)00663-7
https://doi.org/10.1016/s0304-3835(00)00663-7
Autor:
David W. C. Hunt, Agnes H. Chan
Publikováno v:
Expert Opinion on Investigational Drugs. 9:807-817
Photodynamic therapy (PDT) utilises light-absorbing compounds combined with directed photo-irradiation to produce clinical effects. This review updates advances in the understanding of the biochemical pathways triggered by PDT within cells, its influ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0302792d18af6ad5e7f519fc8dc131e5
https://doi.org/10.1517/13543784.9.4.807
https://doi.org/10.1517/13543784.9.4.807
Autor:
Julia G. Levy, Christopher M. Carthy, David W. C. Hunt, Jean-Yves Matroule, David J. Granville, J. Piette, Huijun Jiang, Bruce M. McManus
Publikováno v:
Blood. 95:256-262
The nuclear factor-kappa B (NF-kappaB) gene transactivator serves in the formation of immune, inflammatory, and stress responses. In quiescent cells, NF-kappaB principally resides within the cytoplasm in association with inhibitory kappa (IkappaB) pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c08aa31830099633cb443a9101899a4d
https://doi.org/10.1182/blood.v95.1.256
https://doi.org/10.1182/blood.v95.1.256
Autor:
D. J. Granville, C. M. Carthy, H. Jiang, J. G. Levy, B. M. McManus, J.-Y. Matroule, J. Piette, D. W. C. Hunt
Publikováno v:
Blood. 95:256-262
The nuclear factor-kappa B (NF-κB) gene transactivator serves in the formation of immune, inflammatory, and stress responses. In quiescent cells, NF-κB principally resides within the cytoplasm in association with inhibitory κ (IκB) proteins. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c18a708dfe493f0af81cc1ec7dc9da43
https://doi.org/10.1182/blood.v95.1.256.001k29_256_262
https://doi.org/10.1182/blood.v95.1.256.001k29_256_262