Zobrazeno 1 - 10
of 100
pro vyhledávání: '"W. Brian Reeves"'
Autor:
Travis R. Madaris, Manigandan Venkatesan, Soumya Maity, Miriam C. Stein, Neelanjan Vishnu, Mridula K. Venkateswaran, James G. Davis, Karthik Ramachandran, Sukanthathulse Uthayabalan, Cristel Allen, Ayodeji Osidele, Kristen Stanley, Nicholas P. Bigham, Terry M. Bakewell, Melanie Narkunan, Amy Le, Varsha Karanam, Kang Li, Aum Mhapankar, Luke Norton, Jean Ross, M. Imran Aslam, W. Brian Reeves, Brij B. Singh, Jeffrey Caplan, Justin J. Wilson, Peter B. Stathopulos, Joseph A. Baur, Muniswamy Madesh
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112155- (2023)
Summary: The most abundant cellular divalent cations, Mg2+ (mM) and Ca2+ (nM-μM), antagonistically regulate divergent metabolic pathways with several orders of magnitude affinity preference, but the physiological significance of this competition rem
Externí odkaz:
https://doaj.org/article/324fd2ad3fb9463fa4701a04cb364947
Autor:
Karthik Ramachandran, Soumya Maity, Alagar R. Muthukumar, Soundarya Kandala, Dhanendra Tomar, Tarek Mohamed Abd El-Aziz, Cristel Allen, Yuyang Sun, Manigandan Venkatesan, Travis R. Madaris, Kevin Chiem, Rachel Truitt, Neelanjan Vishnu, Gregory Aune, Allen Anderson, Luis Martinez, Wenli Yang, James D. Stockand, Brij B. Singh, Subramanya Srikantan, W. Brian Reeves, Muniswamy Madesh
Publikováno v:
iScience, Vol 25, Iss 1, Pp 103722- (2022)
Summary: SARS-CoV-2 is a newly identified coronavirus that causes the respiratory disease called coronavirus disease 2019 (COVID-19). With an urgent need for therapeutics, we lack a full understanding of the molecular basis of SARS-CoV-2-induced cell
Externí odkaz:
https://doaj.org/article/6b278b5fe84c471b8072bb9b105a52c6
Autor:
Michael D. Wetzel, Kristen Stanley, Wei Wei Wang, Soumya Maity, Muniswamy Madesh, W. Brian Reeves, Alaa S. Awad
Publikováno v:
JCI Insight, Vol 5, Iss 19 (2020)
Fibrosis is the final common pathway in the pathophysiology of most forms of chronic kidney disease (CKD). As treatment of renal fibrosis still remains largely supportive, a refined understanding of the cellular and molecular mechanisms of kidney fib
Externí odkaz:
https://doaj.org/article/483b48be22c64c11a53ed382f43916ae
Autor:
Wei Wei Wang, Yamei Wang, Kang Li, Raghu Tadagavadi, William E. Friedrichs, Madhusudhan Budatha, W. Brian Reeves, Masaki Mogi
Publikováno v:
PLoS ONE, Vol 15, Iss 9 (2020)
Interleukin-10 (IL-10), a cytokine with anti-inflammatory effects, is produced by renal parenchymal cells and bone marrow derived cells. Both endogenous and exogenous IL-10 are protective in cisplatin-induced acute kidney injury. However, the source
Externí odkaz:
https://doaj.org/article/e0cba930e3f0437fac17d40a52edcb28
Publikováno v:
Toxins, Vol 7, Iss 8, Pp 3245-3256 (2015)
Cisplatin is a very effective chemotherapeutic agent used against a wide range of solid tumors. A major adverse effect of cisplatin therapy is acute kidney injury (AKI). Neutrophils are reported to infiltrate and exacerbate injury in a wide range of
Externí odkaz:
https://doaj.org/article/7c6f97b85c2e4db68f1568deec510893
Publikováno v:
Sensors, Vol 17, Iss 2, p 428 (2017)
Protein biomarkers, especially cytokines, play a pivotal role in the diagnosis and treatment of a wide spectrum of diseases. Therefore, a critical need for advanced cytokine sensors has been rapidly growing and will continue to expand to promote clin
Externí odkaz:
https://doaj.org/article/650f49d6e5a24007bb0315526bf67a39
Publikováno v:
Nature Reviews Nephrology. 17:319-334
Diabetic kidney disease is the leading cause of kidney failure worldwide; in the USA, it accounts for over 50% of individuals entering dialysis or transplant programmes. Unlike other complications of diabetes, the prevalence of diabetic kidney diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51a134f4a613ac68eb086b5de8e47aa7
https://doi.org/10.1038/s41581-021-00393-8
https://doi.org/10.1038/s41581-021-00393-8
Autor:
Yumeng Wen, Heather Thiessen-Philbrook, Dennis G. Moledina, James S. Kaufman, W. Brian Reeves, Nasrollah Ghahramani, T. Alp Ikizler, Alan S. Go, Kathleen D. Liu, Eddie D. Siew, Jonathan Himmelfarb, Paul L. Kimmel, Chi-yuan Hsu, Chirag R. Parikh
Publikováno v:
Kidney international reports, vol 7, iss 7
IntroductionBiomarkers of acute kidney injury (AKI) are often indexed to urine creatinine (UCr) or urine osmolarity (UOsm) to control for urine concentration. We evaluated how these approaches affect the biomarker-outcome association in patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca7a84485c0145724f39ea9083020736
https://pubmed.ncbi.nlm.nih.gov/35812275
https://pubmed.ncbi.nlm.nih.gov/35812275
Publikováno v:
Journal of the American Association for Laboratory Animal Science. 58:21-29
Urinary biomarkers are used increasingly for sensitive prediction of kidney injury in preclinical and clinical studies. Given the frequent requirement of anesthesia in various animal models of disease, it is important to define the effects of anesthe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e52e100e87b97aa8683bae597f617512
https://doi.org/10.30802/aalas-jaalas-18-000062
https://doi.org/10.30802/aalas-jaalas-18-000062
Publikováno v:
Nature reviews. Nephrology. 17(5)
Diabetic kidney disease is the leading cause of kidney failure worldwide; in the USA, it accounts for over 50% of individuals entering dialysis or transplant programmes. Unlike other complications of diabetes, the prevalence of diabetic kidney diseas
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::03c0f483be08a45fbfd048caa5d86215
https://pubmed.ncbi.nlm.nih.gov/33547417
https://pubmed.ncbi.nlm.nih.gov/33547417