Zobrazeno 1 - 10
of 82
pro vyhledávání: '"W. Beesley"'
Autor:
Grant Otto, Robin S.B. Williams, Eleanor C. Warren, Jason S. King, Philip W. Beesley, Devdutt Sharma
Publikováno v:
Autophagy. 15:1407-1418
Mutations in the γ-secretase complex are strongly associated with familial Alzheimer disease. Both proteolytic and non-proteolytic functions for the γ-secretase complex have been previously...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4188774c82b430153eb45b0e326cf1a6
https://doi.org/10.1080/15548627.2019.1586245
https://doi.org/10.1080/15548627.2019.1586245
Autor:
Mair E. W. Beesley, Paul J Vardanega
Publikováno v:
Geotechnical Aspects of Underground Construction in Soft Ground ISBN: 9780429321559
The feasibility of a tunnel, foundation or excavation project is to some extent dependent on limiting the potential ground movements during construction. To make such an assessment it is important to quantify the stress-path dependent behaviour of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8ea66d0993dd66fe98b00afb91824065
https://doi.org/10.1201/9780429321559-28
https://doi.org/10.1201/9780429321559-28
Autor:
Elisa Bozzolan, Paul J Vardanega, Rose Hen-Jones, Elizabeth Holcombe, Charlotte Gilder, Mair E. W. Beesley
Publikováno v:
Understanding and Reducing Landslide Disaster Risk ISBN: 9783030601959
Rainfall-triggered landslides are increasing in the humid tropics, and Small Island Developing States are disproportionately affected. Frequent shallow slides in hillside cuttings along roads and in communities hinder sustainable development. Larger,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0a209ee5a8bec9ebaa9483af4cb5a777
https://doi.org/10.1007/978-3-030-60196-6_49
https://doi.org/10.1007/978-3-030-60196-6_49
Autor:
Marieangela C Wilson, Michaela Kraus, Hassan Marzban, Justyna R Sarna, Yisong Wang, Richard Hawkes, Andrew P Halestrap, Philip W Beesley
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78654 (2013)
BackgroundThe neuroplastins np65 and np55 are two synapse-enriched immunoglobulin (Ig) superfamily adhesion molecules that contain 3 and 2 Ig domains respectively. Np65 is implicated in long term, activity dependent synaptic plasticity, including LTP
Externí odkaz:
https://doaj.org/article/8a5402d4e7c34a948fae30f7768bd5d5
Autor:
Paul J Vardanega, Mair E. W. Beesley
Publikováno v:
Beesley, M E W & Vardanega, P J 2020, ' Parameter variability of undrained shear strength and strain using a database of reconstituted soil tests ', Canadian Geotechnical Journal, vol. 57, no. 8, pp. 1247-1255 . https://doi.org/10.1139/cgj-2019-0424
During construction, the mobilization of undrained shear strength must be limited to avoid soil failure. Soil strains must be controlled to avoid compromising structural serviceability. To assess foundation performance by strength mobilization, an un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34378673863e394ff0b924b8d05ed5f9
https://research-information.bris.ac.uk/ws/files/244733232/cgj_2019_0424.pdf
https://research-information.bris.ac.uk/ws/files/244733232/cgj_2019_0424.pdf
Autor:
Claire L Russell, Sophia Semerdjieva, Ruth M Empson, Brian M Austen, Philip W Beesley, Pavlos Alifragis
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43201 (2012)
It is becoming increasingly evident that deficits in the cortex and hippocampus at early stages of dementia in Alzheimer's disease (AD) are associated with synaptic damage caused by oligomers of the toxic amyloid-β peptide (Aβ42). However, the unde
Externí odkaz:
https://doaj.org/article/4125f04b5b7b43bbb03e4f158d5b869d
Publikováno v:
Recent Advancements on Expansive Soils ISBN: 9783030019136
Prediction of ground movements requires a reliable estimation of soil representative stress-strain behaviour. To do this an assessment of in-situ (‘preshear’) conditions and the associated influence on the average mobilised soil strength and stra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::09bf1bb090f57bd3a71f45991ec03cf4
https://doi.org/10.1007/978-3-030-01914-3_9
https://doi.org/10.1007/978-3-030-01914-3_9
Publikováno v:
Journal of Neurochemistry. 131:268-283
The Neuroplastins Np65 and Np55 are neuronal and synapse-enriched immunoglobulin superfamily molecules that play important roles in a number of key neuronal and synaptic functions including, for Np65, cell adhesion. In this review we focus on the phy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4c3809fce92cae58675ce29810501ad
https://doi.org/10.1111/jnc.12816
https://doi.org/10.1111/jnc.12816
Publikováno v:
The Journal of Physiology. 588:907-922
Cerebellar Purkinje neurones (PNs) express high levels of the plasma membrane calcium ATPase, PMCA2, a transporter protein critical for the clearance of calcium from excitable cells. Genetic deletion of one PMCA2 encoding gene in heterozygous PMCA2 k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6dff7e275b45b29da0c1d2d28bffc29c
https://doi.org/10.1113/jphysiol.2009.182196
https://doi.org/10.1113/jphysiol.2009.182196
Autor:
Anthony Graham, Philip W. Beesley, Richard Bannister, Imelda M. McGonnell, Michael C. Thorndyke
Publikováno v:
Development Genes and Evolution. 218:33-38
The bone morphogenetic proteins (BMPs) are a family of signalling molecules involved in numerous developmental processes including cell fate determination in embryonic ectoderm of vertebrate and invertebrate species. Recently, published evidence has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79d40a4756ab4fdcdd2a54265e921bbd
https://doi.org/10.1007/s00427-007-0193-9
https://doi.org/10.1007/s00427-007-0193-9