Zobrazeno 1 - 10
of 44
pro vyhledávání: '"W. Beau Mitchell"'
Autor:
Lilian Varricchio, Antanas Planutis, Deepa Manwani, Julie Jaffray, W. Beau Mitchell, Anna Rita Migliaccio, James J. Bieker
Publikováno v:
Haematologica, Vol 104, Iss 12 (2019)
Congenital dyserythropoietic anemia type IV is caused by a heterozygous mutation, Glu325Lys (E325K), in the KLF1 transcription factor. Molecular characteristics of this disease have not been clarified, partly due to its rarity. We expanded erythroid
Externí odkaz:
https://doaj.org/article/e187420825ac46e888bd855ac18854de
Autor:
Emmanuelle Godefroy, Yunfeng Liu, Patricia Shi, W. Beau Mitchell, Devin Cohen, Stella T. Chou, Deepa Manwani, Karina Yazdanbakhsh
Publikováno v:
Haematologica, Vol 101, Iss 9 (2016)
Transfusions are the main treatment for patients with sickle cell disease. However, alloimmunization remains a major life-threatening complication for these patients, but the mechanism underlying pathogenesis of alloimmunization is not known. Given t
Externí odkaz:
https://doaj.org/article/b989cb07b5f84040b1c612efc40d7bd2
Autor:
James B. Bussel, W. Beau Mitchell
Publikováno v:
Neonatal Hematology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cedf7fff5930f4e4282af48457a8c07d
https://doi.org/10.1017/9781108773584.016
https://doi.org/10.1017/9781108773584.016
Autor:
W. Beau Mitchell, Deepa Manwani, Antanas Planutis, James J. Bieker, Anna Rita Migliaccio, Lilian Varricchio, Julie Jaffray
Publikováno v:
Haematologica
C ongenital dyserythropoietic anemia type IV is caused by a heterozygous mutation, Glu325Lys (E325K), in the KLF1 transcription factor. Molecular characteristics of this disease have not been clarified, partly due to its rarity. We expanded erythroid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99864b0dfe65e0dd3dfc89e633575305
http://hdl.handle.net/11585/740832
http://hdl.handle.net/11585/740832
Autor:
Henny H. Billett, Ellen J. Silver, Caterina P. Minniti, Kerry A Morrone, Jennifer Davila, Deepa Manwani, W. Beau Mitchell, Sarah H. O'Brien, Payal Desai
Publikováno v:
Blood
Background: The coronavirus disease pandemic of 2019 (COVID-19) has been associated with coagulopathy and an increased rate of thrombosis in adults. Medical practitioners have been prompted to consider prophylactic anticoagulation in special populati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c4a05b0a5e14dd731d98ad6201d9307
https://doi.org/10.1182/blood-2020-137071
https://doi.org/10.1182/blood-2020-137071
Publikováno v:
Transfusion. 56:2941-2947
BACKGROUND Each unit of blood donated is processed and stored individually resulting in variability in the amount of red blood cells (RBCs) collected, RBC properties, and the 24-hour posttransfusion RBC survivability. As a result, each unit differs i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94de737733345950ed0c9d248c999498
https://doi.org/10.1111/trf.13866
https://doi.org/10.1111/trf.13866
Autor:
Oluwasijibomi E. Oluwadara, W. Beau Mitchell, Stephen Fischer, Melissa M. Cushing, Mauro P. Avanzi, Maxwell L. Mitchell
Publikováno v:
Transfusion. 56:170-178
BACKGROUND Platelet (PLT) transfusion is the primary treatment for thrombocytopenia. PLTs are obtained exclusively from volunteer donors, and the PLT product has only a 5-day shelf life, which can limit supply and result in PLT shortages. PLTs derive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de4c9ba1e89e2a0620dd205ff542dd74
https://doi.org/10.1111/trf.13375
https://doi.org/10.1111/trf.13375
Autor:
James B. Bussel, Michelle A. Berny-Lang, Emily Leven, Marc R. Barnard, W. Beau Mitchell, Alan D. Michelson, Andrew L. Frelinger, Hannah Tamary, Anja J. Gerrits, Sophie L. Brigstocke, Shoshana Revel-Vilk, Sabrina L. Carmichael
Publikováno v:
Blood. 126:1367-1378
Because Wiskott-Aldrich syndrome (WAS) and X-linked thrombocytopenia (XLT) patients have microthrombocytopenia, hemorrhage is a major problem. We asked whether eltrombopag, a thrombopoietic agent, would increase platelet counts, improve platelet acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79e922b6bb491f36b81d41f3d076235e
https://doi.org/10.1182/blood-2014-09-602573
https://doi.org/10.1182/blood-2014-09-602573
Publikováno v:
Sickle Cell Disease and Hematopoietic Stem Cell Transplantation ISBN: 9783319623276
Sickle cell disease (SCD) is a complex condition that is characterized by frequent painful episodes. The underlying pathophysiology of vaso-occlusion or VOC is the interactions between the sickle RBCs, endothelium, platelets, neutrophils, and the sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b11c9d3de1f8d1b46487f303610b657
https://doi.org/10.1007/978-3-319-62328-3_2
https://doi.org/10.1007/978-3-319-62328-3_2
Autor:
Surya V. Seshan, James J. Bieker, Connie M. Westhoff, Merlin Nithya Gnanapragasam, Deepa Manwani, W. Beau Mitchell, Julie Jaffray, Xinhuo Guo
Publikováno v:
Blood Cells, Molecules, and Diseases. 51:71-75
KLF1 is an erythroid specific transcription factor that is involved in erythroid lineage commitment, globin switching and terminal red blood cell maturation. Various mutations of KLF1 have been identified in humans, which have led to both benign and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4a0d0a48cfca02e14fc626abf6b06f3
https://doi.org/10.1016/j.bcmd.2013.02.006
https://doi.org/10.1016/j.bcmd.2013.02.006