Zobrazeno 1 - 10
of 69
pro vyhledávání: '"W. B. Weglicki"'
Publikováno v:
Journal of Lipid Research, Vol 19, Iss 1, Pp 18-23 (1978)
Sterile peritoneal exudates produced in rabbits injected with 1% glycogen contain a phospholipase A activity in a cell-free supernatant fraction that hydrolyzed a synthetic phospholipid (1,2-diacyl-sn-glycero-3-phospho-ethanolamine) and phospholipids
Externí odkaz:
https://doaj.org/article/72ada78a78814bcf80dc67a515686544
Publikováno v:
Molecular and Cellular Biochemistry. :167-177
The contribution of mitochondrial free radical production towards the initiation of lipid peroxidation (LPO) and functional injury in the post-ischemic heart is unclear. Using the isolated rat heart model, the effects of the uncoupler of mitochondria
Publikováno v:
Circulation Research. 70:1099-1103
The effects of four calcium channel blockers (nicardipine, nifedipine, verapamil, and diltiazem) on free radical injury in cultured endothelial cells were studied and compared with those of butylated hydroxytoluene. When the cultured cells were expos
Autor:
I T Mak, W B Weglicki
Publikováno v:
Circulation Research. 66:1449-1452
The antiperoxidative activities of nifedipine, verapamil, and diltiazem were compared with that of propranolol by using an in vitro model of sarcolemmal membrane lipid peroxidation. Highly purified sarcolemmal membranes, isolated from canine ventricu
Publikováno v:
Free Radical Research Communications. 9:287-296
Endothelial cells were subjected to anoxia/reoxygenation in order to simulate some of the free radical mechanisms occurring in ischaemia/reperfusion. With ESR and spin trapping using the spin traps 5,5-dimethyl-1-pyrroline-1-oxide (DMPO) and 3,3,5,5-
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 46(8)
We determined whether prior treatment of rats (study 1) with subthreshold doses of iron (no evidence of cardiac tissue overload), or in vitro ischemic pre-conditioning (IP: 5 min. Ischemia (I)/5 min. Reperfusion (R) x 2 cycles) of hearts from untreat
Publikováno v:
Cellular and molecular biology (Noisy-le-Grand, France). 46(8)
The potential anti-radical properties and cytoprotective effects of Mg-gluconate were studied. When microsomal membranes were peroxidized by a *O2- driven, Fe-catalyzed oxy-radical system (R* = dihydroxyfumarate + Fe2+), Mg-gluconate inhibited lipid
Publikováno v:
Molecular and cellular biochemistry. 176(1-2)
Sprague-Dawley rats (200 g) were fed either a Mg-deficient or Mg-sufficient diet for 3 weeks. An enriched neutrophil fraction (85%) was isolated from the blood by sodium metrizoate/dextran gradient centrifugation. Using the superoxide dismutase. (SOD
Publikováno v:
Molecular and cellular biochemistry. 175(1-2)
Spin-trapping techniques combined with electron paramagnetic resonance (EPR) spectroscopy to measure nitric oxide (NO) production were compared in the ischemic-reperfused myocardium for the first time, using both aqueous-soluble and lipophilic comple