Zobrazeno 1 - 10
of 117
pro vyhledávání: '"W. B. Van Den Berg"'
Autor:
W B, van den Berg
Publikováno v:
Arthritis Research
Tumor necrosis factor (TNF) and interleukin-1 (IL-1) are considered to be master cytokines in chronic, destructive arthritis. Therapeutic approaches in rheumatoid arthritis (RA) patients have so far focused mainly on TNF, which is a major inflammator
Autor:
D F G, Remst, A B, Blom, E L, Vitters, R A, Bank, W B, van den Berg, E N, Blaney Davidson, P M, van der Kraan
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.). 66(3)
Synovial fibrosis is a major contributor to joint stiffness in osteoarthritis (OA). Transforming growth factor β (TGFβ), which is elevated in OA, plays a key role in the onset and persistence of synovial fibrosis. However, blocking of TGFβ in OA a
Autor:
I. S. Klasen, Marie-José Melief, G M Bahr, H. de Visser, W. B. Van Den Berg, C G Van Helden-Meeuwsen, M Y Gerrits-Boeye, J. Kool, L. M. C. Van Lieshout, J. G. H. Ruseler-Van Embden
Publikováno v:
Journal of Histochemistry & Cytochemistry. 42:1435-1441
We studied the presence of bacterial antigens in rat tissues. We produced a monoclonal antibody (MAb 2E9) directed against intestinal flora-derived peptidoglycan-polysaccharide complexes from human and rat feces. With several immunological techniques
Autor:
P. A. v. d. Wouw, H. H. v. Rooy, R. W. Koster, A. J. Porsius, R. G. A. van Wayjen, A. van den Ende, R. G. L. van Tol, T. R. MacGregor, J. Mooy, B. c. Arends, R. Böhm, J. v. Kemenade, M. v. Baak, K. H. Rahn, P. P. Koopmans, Th. Thien, C. M. C. Thomas, F. W. J. Gribnau, J. G. Timmer, A. Vyth, W. Th. Kok, J. M. B. V. de Jong, W. A. den Hartog Jager, J. W. P. M. Overdiek, F. H. H. M. Merkus, M. A. van Bàak, D. de Ryckc, O. Teirlynck, M. G. Bogaert, P. Smits, A. van 't Laar, B. A. M. van Schaik, G. G. Geyskes, J. C. Roos, E. J. Dorhout Mees, G. J. Navis, P. E. de Jong, A. J. M. Donker, G. K. v. d. Hem, D. de Zeeuw, A. H. van den Meiracker, A. J. Man in't Veld, C. J. R. Ritsema, null van Eck, F. H. M. Derkx, M. A. D. H. Schalekamp, J. H. M. Berkelmans, H. Wollersheim, A. C. Dullemond-Westland, J. P. Neijt, J. W. R. Nortier, J. M. A. Sitsen, P. Vermeij, P. M. Edelbroek, M. D. Ferrari, O. J. S. Buruma, F. A. de Wolff, F. Elferink, W. J. F. van der Vijgh, I. Klein, W. W. ten Bokkel Huinink, H. M. Pinedo, M. Raghoebar, H. L. G. M. Tiemessen, P. L. C. M. van Kiel, W. B. van den Berg, C. A. M. van Ginneken
Publikováno v:
Pharmacy World & Science. 15:3A-9A
Publikováno v:
Osteoarthritis and cartilage. 18(6)
Alterations in chondrocyte differentiation and matrix remodeling play a central role in osteoarthritis (OA). Chondrocyte differentiation and remodeling are amongst others regulated by the so-called Bone Morphogenetic Proteins (BMPs). Although BMPs ar
Publikováno v:
Osteoarthritis and cartilage. 17(12)
Chondrocytes and alteration in chondrocyte differentiation play a central role in osteoarthritis. Chondrocyte differentiation is amongst others regulated by members of the transforming growth factor-beta (TGF-beta) superfamily. The major intracellula
Publikováno v:
The Netherlands journal of medicine. 64(4)
Autoimmune diseases such as rheumatoid arthritis (RA) result from a deregulation of immune responses culminating in immune-mediated tissue injury. In RA, this tissue injury is mainly reflected by synovitis and subsequent joint damage, although involv
Autor:
K C A M, Nabbe, P, Boross, A E M, Holthuysen, A W, Sloëtjes, J K, Kolls, S, Verbeek, P L E M, van Lent, W B, van Den Berg
Publikováno v:
Arthritis and rheumatism. 52(3)
It has previously been shown that the onset and the degree of joint inflammation during immune complex (IC)-mediated arthritis depend on Fcgamma receptor type III (FcgammaRIII). Local adenoviral overexpression of interferon-gamma (IFNgamma) in the kn
Autor:
W B, van den Berg
Publikováno v:
Clinical and experimental rheumatology. 20(5 Suppl 27)
TNF and IL-1 are master cytokines in chronic destructive arthritis. Therapeutic approaches have so far focused mainly on TNF which is a major inflammatory mediator in RA and a potent inducer of IL-1. Anti-TNF treatment shows great efficacy in RA pati
Publikováno v:
Current directions in autoimmunity. 2