Zobrazeno 1 - 10
of 271
pro vyhledávání: '"W. Arts"'
Autor:
Balázs Erdős, Shauna D. O’Donovan, Michiel E. Adriaens, Anouk Gijbels, Inez Trouwborst, Kelly M. Jardon, Gijs H. Goossens, Lydia A. Afman, Ellen E. Blaak, Natal A. W. van Riel, Ilja C. W. Arts
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Continuous glucose monitoring (CGM) is a promising, minimally invasive alternative to plasma glucose measurements for calibrating physiology-based mathematical models of insulin-regulated glucose metabolism, reducing the reliance on in-clini
Externí odkaz:
https://doaj.org/article/90f5b2ef888142dba762b135172e5e7c
Autor:
Martha F. Endika, David J. M. Barnett, Cynthia E. Klostermann, Noortje Kok, Henk A. Schols, Arjen Nauta, Ilja C. W. Arts, John Penders, Koen Venema, Hauke Smidt
Publikováno v:
Gut Microbiome, Vol 5 (2024)
Breastfeeding represents a strong selective factor for shaping the infant gut microbiota. Besides providing nutritional requirements for the infant, human milk is a key source of oligosaccharides, human milk oligosaccharides (HMOs), and diverse micro
Externí odkaz:
https://doaj.org/article/1c5c10e62ed94ef1b55a83f47bc3edf5
Autor:
Daan van Beek, Job Verdonschot, Kasper Derks, Han Brunner, Theo M. de Kok, Ilja C. W. Arts, Stephane Heymans, Martina Kutmon, Michiel Adriaens
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-8 (2023)
Abstract Allele-specific expression (ASE) analysis detects the relative abundance of alleles at heterozygous loci as a proxy for cis-regulatory variation, which affects the personal transcriptome and proteome. This study describes the development and
Externí odkaz:
https://doaj.org/article/39b6c258cea04013a7a8a15b1d60088e
Autor:
Balázs Erdős, Johan A Westerhuis, Michiel E Adriaens, Shauna D O'Donovan, Ren Xie, Cécile M Singh-Povel, Age K Smilde, Ilja C W Arts
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 6, p e1011221 (2023)
The intricate dependency structure of biological "omics" data, particularly those originating from longitudinal intervention studies with frequently sampled repeated measurements renders the analysis of such data challenging. The high-dimensionality,
Externí odkaz:
https://doaj.org/article/d897f0cf2c064a13967a005048946454
Autor:
Carl Delfin, Iulian Dragan, Dmitry Kuznetsov, Juan Fernandez Tajes, Femke Smit, Daniel E. Coral, Ali Farzaneh, André Haugg, Andreas Hungele, Anne Niknejad, Christopher Hall, Daan Jacobs, Diana Marek, Diane P. Fraser, Dorothee Thuillier, Fariba Ahmadizar, Florence Mehl, Francois Pattou, Frederic Burdet, Gareth Hawkes, Ilja C. W. Arts, Jordi Blanch, Johan Van Soest, José-Manuel Fernández-Real, Juergen Boehl, Katharina Fink, Marleen M. J. van Greevenbroek, Maryam Kavousi, Michiel Minten, Nicole Prinz, Niels Ipsen, Paul W. Franks, Rafael Ramos, Reinhard W. Holl, Scott Horban, Talita Duarte-Salles, Van Du T. Tran, Violeta Raverdy, Yenny Leal, Adam Lenart, Ewan Pearson, Thomas Sparsø, Giuseppe N. Giordano, Vassilios Ioannidis, Keng Soh, Timothy M. Frayling, Carel W. Le Roux, Mark Ibberson
Publikováno v:
Life, Vol 14, Iss 2, p 262 (2024)
Obesity is considered by many as a lifestyle choice rather than a chronic progressive disease. The Innovative Medicines Initiative (IMI) SOPHIA (Stratification of Obesity Phenotypes to Optimize Future Obesity Therapy) project is part of a momentum sh
Externí odkaz:
https://doaj.org/article/343e0c783d8e4fc48237db8466dd4363
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 515 (2023)
Anticytokine autoantibodies (ACAAs) are a fascinating group of antibodies that have gained more and more attention in the field of autoimmunity and secondary immunodeficiencies over the years. Some of these antibodies are characterized by their abili
Externí odkaz:
https://doaj.org/article/1da2412e772f435bb0bb52afcfba4197
Autor:
Martha F. Endika, David J. M. Barnett, Cynthia E. Klostermann, Henk A. Schols, Ilja C. W. Arts, John Penders, Arjen Nauta, Hauke Smidt, Koen Venema
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Antibiotic exposure disturbs the developing infant gut microbiota. The capacity of the gut microbiota to recover from this disturbance (resilience) depends on the type of antibiotic. In this study, infant gut microbiota was exposed to a combination o
Externí odkaz:
https://doaj.org/article/9af2fdd82bb040c7a784cdc54190e810
Autor:
Dennis M. deGraaf, Lisa U. Teufel, Aline H. deNooijer, Adriaan J. vanGammeren, Antonius A. M. Ermens, Ildikó O. Gaál, Tania O. Crișan, Frank L. van deVeerdonk, Mihai G. Netea, Charles A. Dinarello, Leo A. B. Joosten, Rob J. W. Arts, the Radboudumc Center for Infectious Diseases COVID‐19 Study Group
Publikováno v:
Immunity, Inflammation and Disease, Vol 10, Iss 11, Pp n/a-n/a (2022)
Abstract Introduction A major contributor to coronavirus disease 2019 (COVID‐19) progression and severity is a dysregulated innate and adaptive immune response. Interleukin‐38 (IL−38) is an IL‐1 family member with broad anti‐inflammatory pr
Externí odkaz:
https://doaj.org/article/316ee342c38842a0b2005fa7521bb057
Autor:
Eline H. van Roekel, Martijn J. L. Bours, Linda van Delden, Stéphanie O. Breukink, Michèl Aquarius, Eric T. P. Keulen, Audrey Gicquiau, Vivian Viallon, Sabina Rinaldi, Paolo Vineis, Ilja C. W. Arts, Marc J. Gunter, Michael F. Leitzmann, Augustin Scalbert, Matty P. Weijenberg
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract We investigated longitudinal associations of moderate-to-vigorous physical activity (MVPA) and light-intensity physical activity (LPA) with plasma concentrations of 138 metabolites after colorectal cancer (CRC) treatment. Self-reported physi
Externí odkaz:
https://doaj.org/article/65f1b265c8214ed484172de96993f415
Autor:
Lisa U. Teufel, Dennis M. de Graaf, Mihai G. Netea, Charles A. Dinarello, Leo A. B. Joosten, Rob J. W. Arts
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Interleukin (IL)-38 is the latest discovered member of the interleukin-1 family, which has anti-inflammatory properties similar to IL-36Ra. Several studies compared circulating IL-38 concentrations in healthy and diseased populations to characterize
Externí odkaz:
https://doaj.org/article/86943f4fdc194ef38b8d75450095bfb1