Zobrazeno 1 - 10
of 219
pro vyhledávání: '"W. Andy Tao"'
Autor:
Luopin Wang, Aryamav Pattnaik, Subhransu Sekhar Sahoo, Ella G. Stone, Yuxin Zhuang, Annaleigh Benton, Md Tajmul, Srishti Chakravorty, Deepika Dhawan, My An Nguyen, Isabella Sirit, Kyle Mundy, Christopher J. Ricketts, Marco Hadisurya, Garima Baral, Samantha L. Tinsley, Nicole L. Anderson, Smriti Hoda, Scott D. Briggs, Hristos Z. Kaimakliotis, Brittany L. Allen-Petersen, W. Andy Tao, W. Marston Linehan, Deborah W. Knapp, Jason A. Hanna, Matthew R. Olson, Behdad Afzali, Majid Kazemian
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Correctly identifying perturbed biological pathways is a critical step in uncovering basic disease mechanisms and developing much-needed therapeutic strategies. However, whether current tools are optimal for unbiased discovery of relevant pa
Externí odkaz:
https://doaj.org/article/37aa067c964242d3a201f09242539e89
Autor:
Karen G. Cornejo, Andie Venegas, Morgan H. Sono, Madeline Door, Brenda Gutierrez-Ruiz, Lucy B. Karabedian, Supratik G. Nandi, Marco Hadisurya, W. Andy Tao, Emily C. Dykhuizen, Ramendra N. Saha
Publikováno v:
Cell Reports, Vol 43, Iss 11, Pp 114877- (2024)
Summary: Signal-dependent RNA polymerase II (RNA Pol II) productive elongation is an integral component of gene transcription, including that of immediate early genes (IEGs) induced by neuronal activity. However, it remains unclear how productively e
Externí odkaz:
https://doaj.org/article/690f51ce229745159c5131e9d681bef4
Autor:
Jiamin Qiu, Feng Yue, Peipei Zhu, Jingjuan Chen, Fan Xu, Lijia Zhang, Kun Ho Kim, Madigan M. Snyder, Nanjian Luo, Hao-wei Xu, Fang Huang, W. Andy Tao, Shihuan Kuang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Cold stimulation dynamically remodels mitochondria in brown adipose tissue (BAT) to facilitate non-shivering thermogenesis in mammals, but what regulates mitochondrial plasticity is poorly understood. Comparing mitochondrial proteomes in res
Externí odkaz:
https://doaj.org/article/368739ace3b64192beff041c15559b2c
Autor:
Guochen Qin, Menghuan Qu, Bei Jia, Wei Wang, Zhuojun Luo, Chun-Peng Song, W. Andy Tao, Pengcheng Wang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Reversible protein S-nitrosylation regulates a wide range of biological functions and physiological activities in plants. However, it is challenging to quantitively determine the S-nitrosylation targets and dynamics in vivo. In this study, w
Externí odkaz:
https://doaj.org/article/97d2f4dac53e4fe1a436495fd7553612
Autor:
Marco Hadisurya, Li Li, Kananart Kuwaranancharoen, Xiaofeng Wu, Zheng-Chi Lee, Roy N. Alcalay, Shalini Padmanabhan, W. Andy Tao, Anton Iliuk
Publikováno v:
Communications Medicine, Vol 3, Iss 1, Pp 1-19 (2023)
Abstract Background Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene have been recognized as genetic risk factors for Parkinson’s disease (PD). However, compared to cancer, fewer genetic mutations contribute to the cause of PD, propelling
Externí odkaz:
https://doaj.org/article/bb715f3f213548718f0eb37825217e71
Autor:
Xiaohui Li, Peipei Zhu, Yen-Ju Chen, Lei Huang, Diwen Wang, David T. Newton, Chuan-Chih Hsu, Guang Lin, W. Andy Tao, Christopher J. Staiger, Chunhua Zhang
Publikováno v:
Frontiers in Plant Science, Vol 14 (2023)
To sustain normal growth and allow rapid responses to environmental cues, plants alter the plasma membrane protein composition under different conditions presumably by regulation of delivery, stability, and internalization. Exocytosis is a conserved
Externí odkaz:
https://doaj.org/article/4a95d919a1e449e5acd860faeb5e14dd
Autor:
Mayank Srivastava, Ying Zhang, Jian Chen, Devika Sirohi, Andrew Miller, Yang Zhang, Zhilu Chen, Haojie Lu, Jianqing Xu, Richard J. Kuhn, W. Andy Tao
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
The mechanism underlying the cellular entry of Zika virus is not fully understood. Here, the authors use a chemically modified virus and time-resolved proteomics to capture interacting host proteins during virus entry and identify NCAM1 as a ZIKV rec
Externí odkaz:
https://doaj.org/article/e083ebec23fd4782a7cf7d04711ee3c2
Autor:
Qian Wang, Guochen Qin, Min Cao, Rong Chen, Yuming He, Liyuan Yang, Zhejun Zeng, Yongqiang Yu, Yangtao Gu, Weiman Xing, W. Andy Tao, Tongda Xu
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Precise regulation of auxin concentration via transport and metabolism determines the developmental fate of plant tissues. Here the authors show that local auxin biosynthesis is regulated by TMK4-dependent phosphorylation of the TAA1 enzyme and that
Externí odkaz:
https://doaj.org/article/5b625790705041c4acbd9ddeade33c4f
Autor:
Zhen Lin, Yuan Li, Zhengjing Zhang, Xiaolei Liu, Chuan-Chih Hsu, Yanyan Du, Tian Sang, Chen Zhu, Yubei Wang, Viswanathan Satheesh, Pritu Pratibha, Yang Zhao, Chun-Peng Song, W. Andy Tao, Jian-Kang Zhu, Pengcheng Wang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Rapid activation of SnRK2 kinases is central to plant responses to osmotic stress and abscisic acid. Here the authors show that a group of Raf-like kinases are very quickly activated by osmotic stress, and then phosphorylate and activate SnRK2s.
Externí odkaz:
https://doaj.org/article/06d5c1664ba0430b88a579d8e6e1176d
Autor:
Hao Zhang, Gui-Yuan Zhang, Wei-Chao Su, Ya-Ting Chen, Yu-Feng Liu, Dong Wei, Yan-Xi Zhang, Qiu-Yi Tang, Yu-Xiang Liu, Shi-Zhi Wang, Wen-Chao Li, Anke Wesselius, Maurice P. Zeegers, Zi-Yu Zhang, Yan-Hong Gu, W. Andy Tao, Evan Yi-Wen Yu
Publikováno v:
Molecules, Vol 27, Iss 23, p 8155 (2022)
Proteomic profiling of extracellular vesicles (EVs) represents a promising approach for early detection and therapeutic monitoring of diseases such as cancer. The focus of this study was to apply robust EV isolation and subsequent data-independent ac
Externí odkaz:
https://doaj.org/article/ffe888f19d4f4e2c80eb6d8344dd42c6