Zobrazeno 1 - 10
of 87
pro vyhledávání: '"W. Andrew Yeudall"'
Autor:
Catherine A. Vaughan, Shilpa Singh, Mark A. Subler, Jolene J. Windle, Kazushi Inoue, Elizabeth A. Fry, Raghavendra Pillappa, Steven R. Grossman, Brad Windle, W. Andrew Yeudall, Swati Palit Deb, Sumitra Deb
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
The mechanisms of how gain-of-function (GOF) mutant p53 drives carcinogenesis are unclear. Here, the authors show that a GOF mutant p53 requires its transactivation capability to induce mouse lung tumors and this is dependent on PLK3 phosphorylation
Externí odkaz:
https://doaj.org/article/54a056e3c31c4f638609e87d39e9e921
Autor:
Sinem Esra Sahingur, W. Andrew Yeudall
Publikováno v:
Frontiers in Immunology, Vol 6 (2015)
The chemotactic cytokines, or chemokines, comprise a superfamily of polypeptides with a wide range of activities that include recruitment of immune cells to sites of infection and inflammation, as well as stimulation of cell proliferation. As such, t
Externí odkaz:
https://doaj.org/article/4316ac29c40940f68a058855f165bd42
Autor:
Évila Lopes Salles, Sahar Emami Naeini, Hesam Khodadadi, Bidhan Bhandari, Sholeh Rezaee, Edie Threlkeld, Hannah M. Rogers, Vincenzo Costigliola, Alvin V. Terry, David C. Hess, Sumitra Deb, Swati Palit Deb, W. Andrew Yeudall, Jack C. Yu, Lei P. Wang, Babak Baban
Publikováno v:
Human Cell. 36:1204-1210
Autor:
W. Andrew Yeudall, Zendra E. Zehner, J. Silvio Gutkind, Ahmad Waseem, Vyomesh Patel, Hiroshi Miyazaki, Rachel J. Paccione
Supplementary Table S1 from Keratin down-regulation in vimentin-positive cancer cells is reversible by vimentin RNA interference, which inhibits growth and motility
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47f4662539fabbb7b0276b189fc21db5
https://doi.org/10.1158/1535-7163.22485516.v1
https://doi.org/10.1158/1535-7163.22485516.v1
Autor:
Hesam Khodadadi, Évila Lopes Salles, Ahmet Alptekin, Daniel Mehrabian, Martin Rutkowski, Ali S. Arbab, W. Andrew Yeudall, Jack C. Yu, John C. Morgan, David C. Hess, Kumar Vaibhav, Krishnan M. Dhandapani, Babak Baban
Publikováno v:
Cannabis and cannabinoid research.
Publikováno v:
British Journal of Cancer
BackgroundEPS8 is a scaffolding protein that regulates proliferation, actin dynamics and receptor trafficking. Its expression is increased in cancer, enhancing mitogenesis, migration and tumorigenesis. Src phosphorylates EPS8 at four tyrosine residue
Autor:
Linah A. Shahoumi, W. Andrew Yeudall
Publikováno v:
EPMA J
Head and neck squamous cell carcinoma (HNSCC) develops in the mucosal lining of the upper aerodigestive tract, principally as a result of exposure to carcinogens present in tobacco products and alcohol, with oncogenic papillomaviruses also being reco
Autor:
Shilpa Singh, Brad Windle, Sumitra Deb, Elizabeth A. Fry, Jolene J. Windle, W. Andrew Yeudall, Kazushi Inoue, Swati Palit Deb, Catherine A. Vaughan, Steven R. Grossman, Mark A. Subler, Raghavendra Pillappa
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
p53 mutations with single amino acid changes in cancer often lead to dominant oncogenic changes. Here, we have developed a mouse model of gain-of-function (GOF) p53-driven lung cancer utilizing conditionally active LSL p53-R172H and LSL K-Ras-G12D kn
Publikováno v:
Frontiers in Oral Health
Publikováno v:
Journal of Molecular Medicine. 96:929-938
The functional relationship between apoptosis and autophagy in anticancer drug treatment is extremely complex, and the molecular machinery is obscure. This study aims to investigate the efficacy of CYT997, a novel microtubule-disrupting agent, in hea