Zobrazeno 1 - 10
of 565
pro vyhledávání: '"W. Anders"'
Publikováno v:
Physical Review Special Topics. Accelerators and Beams, Vol 13, Iss 8, p 082001 (2010)
Many proposals for next generation light sources based on single pass free electron lasers or energy recovery linac facilities require a continuous wave (cw) driven superconducting linac. The effective beam loading in such machines is very small and
Externí odkaz:
https://doaj.org/article/58e74a54bcc24b10985c85467a12408a
Autor:
Marion W. Anders, Philip G. Board
Publikováno v:
Drug metabolism reviews. 53(1)
Drug metabolizing enzymes catalyze the biotransformation of many of drugs and chemicals. The drug metabolizing enzymes are distributed among several evolutionary families and catalyze a range of detoxication reactions, including oxidation/reduction,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff6755668d310b580eff96d674a12815
https://pubmed.ncbi.nlm.nih.gov/33264039
https://pubmed.ncbi.nlm.nih.gov/33264039
Autor:
M. W. Anders, Patrick E. Hanna
Publikováno v:
Critical reviews in toxicology. 49(10)
The mercapturic acid pathway is a major route for the biotransformation of xenobiotic and endobiotic electrophilic compounds and their metabolites. Mercapturic acids (N-acetyl-l-cysteine S-conjugates) are formed by the sequential action of the glutat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2dbe7b9c6976865cf3226ae42a8fb59
https://pubmed.ncbi.nlm.nih.gov/31944156
https://pubmed.ncbi.nlm.nih.gov/31944156
Autor:
Alan V. Smrcka, Laura L. Bahr, M. W. Anders, Andrew P. Wojtovich, Gregory G. Tall, Hannah M. Stoveken
Publikováno v:
Molecular Pharmacology. 90:214-224
Adhesion G protein–coupled receptors (aGPCRs) have emerging roles in development and tissue maintenance and is the most prevalent GPCR subclass mutated in human cancers, but to date, no drugs have been developed to target them in any disease. aGPCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a3c180ea582db4c89772556b477dc63
https://doi.org/10.1124/mol.116.104828
https://doi.org/10.1124/mol.116.104828
Autor:
Ella W. Anders
In der Pension LINDA, einer der »teuersten Frühstückspensionen Bad Füssings«, geht die Post ab, als der attraktive Kurgast Marc Duvall nach seinem tödlichen Verkehrsunfall posthum seine Hotelrechnung in bar bezahlt und das leerstehende Zimmer f
Autor:
Ella W. Anders
Im Nobel-Hotel BAYERN-Inn sind die fünf Sterne am Sinken. Ein zweifacher Mord ängstigt die Gäste und lässt sie in Panik aus dem »Mord-Hotel« in die umliegenden Pensionen fliehen. Die Stunde ist günstig für Ludwig Kugelmoser, den verwitweten A
Publikováno v:
Synthetic Communications. 43:1-8
The syntheses of 3-(1-methyl-1H-imidazol-2-ylthio)acrylic acid and 3-(1-methyl-1H-imidazol-2-ylthio)propanoic acid, mitochondria-targeted prodrugs of the antioxidant methimazole, are described. The method of Fan et al. (Fan et al., Synthesis 2006, 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::574ce3d3967b017d084c11dacdce68b5
https://doi.org/10.1080/00397911.2011.587078
https://doi.org/10.1080/00397911.2011.587078
Autor:
M. W. Anders
Publikováno v:
Chemico-Biological Interactions. 192:8-13
The goal of this research was to test the hypothesis that bioactivation reactions could be exploited to deliver and activate mitochondria-targeted antioxidant prodrugs. The concept that bioactivation reactions could be used for prodrug delivery and a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b807d459273c2010e59b48c703ff745
https://doi.org/10.1016/j.cbi.2010.10.004
https://doi.org/10.1016/j.cbi.2010.10.004
Autor:
Jalil Shojaie, Leif P. Olson, M. W. Anders, Kurt S. Roser, Richard L. Parton, Paul S. Brookes, Andrew P. Wojtovich
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:1441-1448
Mitochondrial reactive oxygen species (ROS) generation and the attendant mitochondrial dysfunction are implicated in a range of disease states. The objective of the present studies was to test the hypothesis that the mitochondrial beta-oxidation path
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::440021945c5e75c013bd2e8bd9bc83b5
https://doi.org/10.1016/j.bmc.2010.01.019
https://doi.org/10.1016/j.bmc.2010.01.019
Autor:
Aaron J. Oakley, Marjorie Coggan, Marion W. Anders, Philip G. Board, Jean Cappello, Huina Zhou
Publikováno v:
Analytical Biochemistry. 374:25-30
Glutathione transferase omega 1-1 (GSTO1-1) catalyzes the biotransformation of arsenic and is implicated as a factor influencing the age-at-onset of Alzheimer's disease and the posttranslational activation of interleukin 1beta (IL-1beta). Investigati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2879f897162d763c8486dc1dc3c568e6
https://doi.org/10.1016/j.ab.2007.09.029
https://doi.org/10.1016/j.ab.2007.09.029