Výsledky vyhledávání - "W. A. Van Sickle"

Akademický článek

Effect of fasting on the composition of plasma lipoproteins in cholesterol-fed diabetic rabbits.

Autor: W A Van Sickle, P Brecher, A Aspen, A V Chobanian

Publikováno v: Journal of Lipid Research, Vol 26, Iss 4, Pp 442-450 (1985)

Cholesterol-fat feeding is associated with unusual alterations in the composition of plasma lipoproteins in alloxan-diabetic rabbits. In the present study plasma lipoprotein lipid and apoprotein composition was studied before and after 48 hr of fasti

Externí odkaz: https://doaj.org/article/7598cf3c9b984492bd23dd75ebde8e97

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Akademický článek

High density lipoprotein-induced cardiac prostacyclin synthesis in vitro: relationship to cardiac arachidonate mobilization.

Autor: W A Van Sickle, H G Wilcox, K U Malik, A Nasjletti

Publikováno v: Journal of Lipid Research, Vol 27, Iss 5, Pp 517-522 (1988)

The objectives of this study were to characterize the effects of plasma lipoproteins on prostacyclin (PGI2) production by the Langendorff-perfused rabbit heart, and to determine the mechanism of lipoprotein-induced cardiac PGI2 production. PGI2 produ

Externí odkaz: https://doaj.org/article/7f1e261765ab419b8a30926a235dc602

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Antioxidant activity of probucol and its analogs in hypercholesterolemic Watanabe rabbits

Autor: Mao Simon J T, A. E. Rechtin, Mark T. Yates, R. L. Jackson, W. A. Van Sickle

Publikováno v: Journal of Medicinal Chemistry. 34:298-302

Probucol (1) and probucol analogues with the substitutions at the disulfide-linked carbon (2, 3) and an additional substitution at a tert-butyl of each phenolic ring (4) were tested for their ability to lower total serum cholesterol and prevent aorti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f71cabe3ad5da277cb2809a9e62971cd
https://doi.org/10.1021/jm00105a046

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An alternative mechanism for the inhibition of cholesterol biosynthesis in HepG2 cells by N-[(1,5,9)-trimethyldecyl]-4 alpha,10-dimethyl-8-aza-trans-decal-3 beta-ol (MDL 28,815)

Autor: W A, Van Sickle, P K, Wilson, M W, Wannamaker, J R, Cooper, M A, Flanagan, J R, McCarthy, P, Bey, R L, Jackson

Publikováno v: The Journal of pharmacology and experimental therapeutics. 267(3)

Compounds that block hepatic cholesterol biosynthesis and secretion may be useful hypocholesterolemic agents. N-[(1,5,9)-trimethyldecyl]-4 alpha,10-dimethyl-8-aza-trans-decal-3 beta-ol (MDL 28,815) has been shown to block cholesterol biosynthesis in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::230b5c0be71ef642f35eb5bc4585a28e
https://pubmed.ncbi.nlm.nih.gov/8263786

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N-(1-oxododecyl)-4 alpha,10-dimethyl-8-aza-trans-decal-3 beta-ol: a potent competitive inhibitor of 2,3-oxidosqualene cyclase

Autor: P K Wilson, William R. Moore, James R. McCarthy, Philip P. Waid, Marion W. Wannamaker, W. A. Van Sickle, Gerald L. Schatzman

Publikováno v: Journal of medicinal chemistry. 35(19)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ba94fa6bb43fce5cccc2705f0c984f
https://pubmed.ncbi.nlm.nih.gov/1404239

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Inhibition of cholesterol synthesis by cyclopropylamine derivatives of squalene in human hepatoblastoma cells in culture

Autor: J. R. Cooper, P K Wilson, W. A. Van Sickle, M. A. Flanagan, A. Marquart, M. R. Angelastro

Publikováno v: Lipids. 27(3)

Two squalene derivatives, trisnorsqualene cyclopropylamine and trisnorsqualene N-methylcyclopropylamine, were synthesized and tested for inhibition of lanosterol and squalene epoxide formation from squalene in rat hepatic microsomes, and for the inhi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932d668460ebbec6673529ee5a6fd637
https://pubmed.ncbi.nlm.nih.gov/1326069

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Evaluation of a Cougar Population Estimator Based on Probability Sampling

Autor: W. D. Van Sickle, Frederick G. Lindzey

Publikováno v: The Journal of Wildlife Management. 55:738

We used probability sampling of snow tracks which were located from the air as a method of estimating cougar (Felis concolor) numbers. Computer-simulated surveys were conducted on empirical movement data from a known population of cougars to evaluate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9749063207c68f32c20a4a0b99b63bd9
https://doi.org/10.2307/3809526

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Relationship of an abnormal plasma lipoprotein to protection from atherosclerosis in the cholesterol-fed diabetic rabbit

Autor: Peter Brecher, Donald Small, W A Van Sickle, Ann Tercyak, J Baler, Aram V. Chobanian, A Lazzari

Publikováno v: Journal of Clinical Investigation. 72:1553-1562

Alloxan-diabetic rabbits develop a pronounced hypercholesterolemia and hypertriglyceridemia in response to cholesterol feeding. Despite higher levels of plasma cholesterol, these animals have much less atherosclerosis than cholesterol-fed nondiabetic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1125138d4cb12cd703b729ee469d468b
https://doi.org/10.1172/jci111114

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High density lipoprotein-induced cardiac prostacyclin synthesis in vitro: relationship to cardiac arachidonate mobilization

Autor: K. U. Malik, W A Van Sickle, Henry G. Wilcox, Alberto Nasjletti

Publikováno v: Journal of Lipid Research, Vol 27, Iss 5, Pp 517-522 (1988)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a33f1aa4c1ee21e6dd11a43f376cff5a
http://www.sciencedirect.com/science/article/pii/S0022227520351890

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