Systemic infection and microglia activation: a prospective postmortem study in sepsis patients

Autor: D. Westhoff, J. Y. Engelen-Lee, I. C. M. Hoogland, E. M. A. Aronica, D. J. van Westerloo, D. van de Beek, W. A. van Gool

Publikováno v: Immunity & Ageing, Vol 16, Iss 1, Pp 1-10 (2019)

Abstract Background Systemic infection is associated with long-term cognitive deficits and functional decline. In this study we hypothesized that severe systemic inflammation leads to a neuroinflammatory response that is characterized by microglial a

Externí odkaz: https://doaj.org/article/7c854e68eae24d32af152c841ccd96ad

Realistic evaluation of the Flexmonitor, a team program to maintain and reflect on flexibility

Autor: Frank W R van Gool, Joyce J.P.A. Bierbooms, Inge Bongers, Richard Janssen

Publikováno v: Journal of Health Organization and Management, 35(4), 409-424. Emerald Group Publishing Ltd.

PurposeFlexibility is necessary in a dynamic healthcare environment. However, balancing flexibility and consistency is difficult for healthcare teams, especially when working in threatening conditions. Methods are needed to help teams create, monitor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3650fefe11d70136fe39ffdc3649cc2f
https://doi.org/10.1108/jhom-04-2020-0109

Co-creating a program for teams to maintain and reflect on their flexibility

Autor: Frank W R van Gool, Inge Bongers, Joyce J.P.A. Bierbooms, Richard Janssen

Publikováno v: International Journal of Health Planning and Management, 34(4), e1937-e1947. Wiley-Blackwell
International Journal of Health Planning and Management, 1-11. John Wiley & Sons Ltd.
STARTPAGE=1;ENDPAGE=11;ISSN=0749-6753;TITLE=International Journal of Health Planning and Management

To prevent rigidity within teams in health care and to support teams in detecting early warning signs of decreasing flexibility, a program has been co-created in collaboration with mental healthcare teams. This program is intended to systematically m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f819984b5522528bfa4b3931a00daa49
https://research.tilburguniversity.edu/en/publications/b0cdf539-9cae-4fbf-9481-c0ec30a97ba8

[Is dementia preventable through intensive vascular care? The preDIVA trial]

Autor: E P, Moll van Charante, E, Richard, L S, Eurelings, J W, van Dalen, S A, Ligthart, E F, van Bussel, M P, Hoevenaar-Blom, M, Vermeulen, W A, van Gool

Publikováno v: Nederlands tijdschrift voor geneeskunde. 161

To assess whether intensive vascular care in GP practices can prevent dementia in a population of community-dwelling older people.This pragmatic cluster-randomised open-label study (ISRCTN29711771) was conducted in persons aged 70-78 years who were r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e8de59bc076d0f921c76381ce3b6a660
https://pubmed.ncbi.nlm.nih.gov/28488553

Emerging Treatments in Dementia

Autor: P. Scheltens, W. A. Van Gool

Publikováno v: European neurology, 38(3), 184-189. S. Karger AG

Dementia is one of the most common organic mental syndromes, usually caused by Alzheimer's disease (AD) or vascular dementia (VD) or both. Regarding AD we review the state or the art of the cholinergic approach and discuss some future options regardi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5d188b9436f1ba4e6c6e62b880f8a85
https://doi.org/10.1159/000113372