Zobrazeno 1 - 10
of 143
pro vyhledávání: '"W. A. Gates"'
Autor:
Eric W. J. Gates, Kian Mansour, Sahar Ebrahimi Samani, Sammir Shad, Mari T. Kaartinen, Jeffrey W. Keillor
Publikováno v:
Molecules, Vol 28, Iss 4, p 1634 (2023)
Factor XIIIa (FXIIIa) is a transglutaminase of major therapeutic interest for the development of anticoagulants due to its essential role in the blood coagulation cascade. While numerous FXIIIa inhibitors have been reported, they failed to reach clin
Externí odkaz:
https://doaj.org/article/e92054fde8f9454ab0c53c53e73e74ef
Autor:
Nicholas J. Cundy, Jane Arciszewski, Eric W. J. Gates, Sydney L. Acton, Kyle D. Passley, Ernest Awoonor-Williams, Elizabeth K. Boyd, Nancy Xu, Élise Pierson, Catalina Fernandez-Ansieta, Marie R. Albert, Nicole M. R. McNeil, Gautam Adhikary, Richard L. Eckert, Jeffrey W. Keillor
Publikováno v:
RSC Medicinal Chemistry. 14:378-385
A novel peptidic scaffold was used to design a library of inhibitors that exhibit exceptional efficiency against tissue transglutaminase, providing a framework for the development of potent research tools.
Autor:
Alana M. M. Rangaswamy, Pauline Navals, Eric W. J. Gates, Sammir Shad, Sarah K. I. Watt, Jeffrey W. Keillor
Publikováno v:
RSC Med Chem
Tissue transglutaminase (TG2) is a multifunctional protein that plays biological roles based on its ability to catalyse protein cross-linking and to function as a non-canonical G-protein known as Ghα. The non-regulated activity of TG2 has been impli
Autor:
Rita, Canella, Federica, Brugnoli, Mariana, Gallo, Jeffrey W, Keillor, Anna, Terrazzan, Elena, Ferrari, Silvia, Grassilli, Eric W J, Gates, Stefano, Volinia, Valeria, Bertagnolo, Nicoletta, Bianchi, Carlo M, Bergamini
Publikováno v:
Cancers. 15(1)
Since the multifunctionality of transglutaminase 2 (TG2) includes extra- and intracellular functions, we investigated the effects of intracellular administration of TG2 inhibitors in three breast cancer cell lines, MDA-MB-231, MDA-MB-436 and MDA-MB-4
Publikováno v:
Geotechnical Testing Journal. 45:20200168
Autor:
W. Lawrence Gates
Publikováno v:
Toward Understanding Climate Change ISBN: 9780429269295
Toward Understanding Climate Change
Toward Understanding Climate Change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8bbb77e8686441a325cf54d895e40a5
https://doi.org/10.4324/9780429269295-2
https://doi.org/10.4324/9780429269295-2
Publikováno v:
The Journal of prosthetic dentistry. 122(3)
Statement of problem Implant therapy involving an unsplinted 2-implant–retained overdenture is well defined as a successful treatment for a patient with an edentulous mandible. However, a similar unsplinted implant therapy supporting a maxillary ov
Autor:
J. W. C. Gates
Publikováno v:
The Photogrammetric Record. 11:267-279
An individual view is provided of the function of the art and science of photogrammetry, over the whole of the history of attempts to make measurements from optical observations. The predominating influence, in past years, of the need for mapping fro
Publikováno v:
The Photogrammetric Record. 9:5-23
The International Society for Photogrammetry held the XIIIth International Congress at Helsinki Technical University during July 1976. The contributors to this report spoke about the work of the technical commissions and the content of the commercial
Autor:
Richard Eckard, Peter Grace, W. P. Gates, F. Barker-Reid, Kevin T. Kelly, M. Meyer, Ian E. Galbally, S. Bentley, Ray Leuning, I.A. Weeks, Frances Phillips, R. Baigent
Publikováno v:
Environmental Sciences. 2:133-142
Australian climate, soils and agricultural management practices are significantly different from those of the northern hemisphere nations. Consequently, experimental data on greenhouse gas production from European and North American agricultural soil