Zobrazeno 1 - 10
of 46
pro vyhledávání: '"W. A. Colburn"'
Autor:
W. S. Colburn, E. N. Tompkins
Publikováno v:
Applied optics. 13(12)
Thermoplastic-photoconductor devices are attractive for holographic recording because of their relatively high sensitivities, efficient holograms, and record-erase capabilities. Recent improvements in charging techniques and in the thermoplastic mate
Autor:
W. S. Colburn, K. A. Haines
Publikováno v:
Applied optics. 10(7)
Holograms have been constructed in photopolymer materials which give bright, low-noise images. These holograms are of the volume type and have no surface variations in all but a few special cases. They are constructed in virtually real time and in si
Publikováno v:
Engineering, Construction, and Operations in Challenging Environments.
Autor:
A, Hoque, S M, Lippman, I V, Boiko, E N, Atkinson, N, Sneige, A, Sahin, D M, Weber, S, Risin, M D, Lagios, R, Schwarting, W J, Colburn, K, Dhingra, M, Follen, G J, Kelloff, C W, Boone, W N, Hittelman
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 10(3)
Clinical management of ductal carcinoma in situ (DCIS) remains a challenge because significant proportions of patients experience recurrence after conservative surgical treatment. Unfortunately, it is difficult to prospectively identify, using object
Autor:
W A, Colburn
Publikováno v:
Journal of clinical pharmacology. 40(12 Pt 2)
Biomarkers and surrogate endpoints are critical to the future of efficient drug development. Definitions, a conceptual model, and a conceptual framework for validating and bridging biomarkers to clinical endpoints are provided in this presentation. I
Autor:
H, Derendorf, L J, Lesko, P, Chaikin, W A, Colburn, P, Lee, R, Miller, R, Powell, G, Rhodes, D, Stanski, J, Venitz
Publikováno v:
Journal of clinical pharmacology. 40(12 Pt 2)
The two domains in clinical pharmacology dealing with optimizing dosing recommendations are pharmacokinetics and pharmacodynamics. However, the usefulness of these disciplines is limited if viewed in isolation. Pharmacokinetic/pharmacodynamic (PK/PD)
Autor:
S K, Teo, M R, Scheffler, K A, Kook, W G, Tracewell, W A, Colburn, D I, Stirling, S D, Thomas
Publikováno v:
Biopharmaceuticsdrug disposition. 21(1)
The effect of food on the oral pharmacokinetics of thalidomide and the relative bioavailability of two oral thalidomide formulations were determined in an open label, single dose, randomized, three-way crossover study. Five male and eight female heal
Autor:
W A, Colburn, D L, Keefe
Publikováno v:
Journal of clinical pharmacology. 40(6)
Publikováno v:
Journal of clinical pharmacology. 39(11)
Thalidomide was recently approved in the United States for the treatment of erythema nodosum leprosum, a complication of leprosy. The present study determined the bioequivalence and pharmacokinetics of Celgene's commercial and clinical trial thalidom
Autor:
W A, Colburn
Publikováno v:
Journal of clinical pharmacology. 39(5)