Výsledky vyhledávání

Tumor necrosis factor-α elevates neurite outgrowth through an NF-κB-dependent pathway in cultured adult sensory neurons: Diminished expression in diabetes may contribute to sensory neuropathy

Autor: Savitha Balakrishnan, Corina Martens, Paul Fernyhough, Darrell R. Smith, Lori Dunn, Ali Saleh, Christopher W. Tweed

Publikováno v: Brain Research. 1423:87-95

The presence of a proinflammatory environment in the sensory neuron axis in diabetes was tested by measuring levels of proinflammatory cytokines in lumbar dorsal root ganglia (DRG) and peripheral nerve from age matched control and streptozotocin (STZ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::901cb920a557f6bb13d8f312193276f3
https://doi.org/10.1016/j.brainres.2011.09.029

Zobrazit plný text záznamu

Nuclear Factor-κB Activation in Axons and Schwann Cells in Experimental Sciatic Nerve Injury and Its Role in Modulating Axon Regeneration: Studies With Etanercept

Autor: Paul Fernyhough, Christopher W. Tweed, Gordon W. Glazner, Darrell R. Smith

Publikováno v: Journal of Neuropathology and Experimental Neurology. 68:691-700

An increasing weight of evidence implicates early inflammatory events as inhibitors of functional recovery in both peripheral and central neuropathologies. In this study, we investigated the role of the inflammatory TNF-α/NF-κB axis on events subse

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::019e8606e2729a77075c6e037a17e71d
https://doi.org/10.1097/nen.0b013e3181a7c14e

Zobrazit plný text záznamu

Inhibition of gene markers of fibrosis with a novel inhibitor of transforming growth factor-beta type I receptor kinase in puromycin-induced nephritis

Autor: David P. Brooks, Nicholas J. Laping, John D. Harling, Christopher W. Tweed, William M. Martin, Eugene T. Grygielko, Peter P. Thornton

Publikováno v: The Journal of pharmacology and experimental therapeutics. 313(3)

SB-525334 (6-[2-tert-butyl-5-(6-methyl-pyridin-2-yl)-1H-imidazol-4-yl]-quinoxaline) has been characterized as a potent and selective inhibitor of the transforming growth factor-beta1 (TGF-beta1) receptor, activin receptor-like kinase (ALK5). The comp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f82d2ccc0fcd2bf8f662665cae8b00b
https://pubmed.ncbi.nlm.nih.gov/15769863

Zobrazit plný text záznamu

Activation of Nuclear Factor-κB via Endogenous Tumor Necrosis Factor α Regulates Survival of Axotomized Adult Sensory Neurons

Autor: Paul Fernyhough, Natalie J. Gardiner, Randy Van der Ploeg, Lyle Freeman, Jason Schapansky, Christopher W. Tweed, Andreas Kontos, Darrell R. Smith, Tertia D. Purves-Tyson, Gordon W. Glazner

Publikováno v: The Journal of Neuroscience, 25(7), 1682-1690. Oxford University Press

Embryonic dorsal root ganglion (DRG) neurons die after axonal damage in vivo, and cultured embryonic DRG neurons require exogenous neurotrophic factors that activate the neuroprotective transcription factor nuclear factor-kappaB(NF-kappaB) for surviv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2458e098a2b0b794587c6441c0a7f4c3
https://europepmc.org/articles/PMC6725919/

Zobrazit plný text záznamu

Gender differences in methamphetamine-induced mRNA associated with neurodegeneration in the mouse nigrostriatal dopaminergic system

Autor: Dean E. Dluzen, Linda I. Anderson, Nicholas J. Laping, Christopher W. Tweed

Publikováno v: Neuroendocrinology. 77(4)

In this report female and male CD-1 mice were treated with a neurotoxic regimen of methamphetamine (MA) to compare gender differences in striatal dopamine depletion and concordant changes in mRNA markers of the transforming growth factor-β injury re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e7e4866ac53c7fd98dbd1daa5534012
https://pubmed.ncbi.nlm.nih.gov/12766323

Zobrazit plný text záznamu

Operating Constants for Direct‐Current Thermionic Amplifiers

Autor: T. W. Tweed, P. A. Macdonald

Publikováno v: Physics. 4:178-183

The sensitivity to voltage, measured in volts per mm scale deflection, of a direct‐current thermionic amplifier (simple circuit) is taken as inversely proportional to the mutual conductance divided by the plate current of the valve employed. The mu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d985a99552e503ad1e02598516159f84
https://doi.org/10.1063/1.1745176

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání