Zobrazeno 1 - 10
of 1 668
pro vyhledávání: '"W Tucker"'
Autor:
Xueyi Chen, Bhavatharini Arun, Oscar J. Nino-Meza, Mona O. Sarhan, Medha Singh, Byeonghoon Jeon, Kishor Mane, Maunank Shah, Elizabeth W. Tucker, Laurence S. Carroll, Joel S. Freundlich, Charles A. Peloquin, Vijay D. Ivaturi, Sanjay K. Jain
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Tuberculosis (TB) remains a leading cause of death, but antibiotic treatments for tuberculous meningitis, the deadliest form of TB, are based on those developed for pulmonary TB and not optimized for brain penetration. Here, we perform first
Externí odkaz:
https://doaj.org/article/12b747e27b024b34afbe5771b810380b
Autor:
John Kim, Ian Spears, Clara Erice, Hye-Young H. Kim, Ned A. Porter, Caitlin Tressler, Elizabeth W. Tucker
Publikováno v:
Neurobiology of Disease, Vol 202, Iss , Pp 106721- (2024)
Tuberculous (TB) meningitis is the deadliest form of extrapulmonary TB which disproportionately affects children and immunocompromised individuals. Studies in pulmonary TB have shown that Mycobacterium tuberculosis can alter host lipid metabolism to
Externí odkaz:
https://doaj.org/article/ddedd996dfea47ca90a8bdd08de80f30
Autor:
Ana Paula Serafini Poeta Silva, Robert Mugabi, Marisa L. Rotolo, Seth Krantz, Dapeng Hu, Rebecca Robbins, Deanne Hemker, Andres Diaz, A. W. Tucker, Rodger Main, Jean Paul Cano, Perry Harms, Chong Wang, Maria Jose Clavijo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Tracheal pooling for Mycoplasma hyopneumoniae (M. hyopneumoniae) DNA detection allows for decreased diagnostic cost, one of the main constraints in surveillance programs. The objectives of this study were to estimate the sensitivity of poole
Externí odkaz:
https://doaj.org/article/70f0d1cf6f564ac9a87682fbdaf74b92
Autor:
Robert Mugabi, Ana Paula S. Poeta Silva, Xiao Hu, Marcelo Gottschalk, Virginia Aragon, Nubia R. Macedo, Orhan Sahin, Perry Harms, Rodger Main, Alexander W. Tucker, Ganwu Li, Maria J. Clavijo
Publikováno v:
BMC Veterinary Research, Vol 19, Iss 1, Pp 1-13 (2023)
Abstract Background Glaesserella parasuis is the causative agent of Glässer’s disease in pigs. Serotyping is the most common method used to type G. parasuis isolates. However, the high number of non-typables (NT) and low discriminatory power make
Externí odkaz:
https://doaj.org/article/e7155930f4db4e06b2e84fed2669a31f
Autor:
Wesley W. Tucker, Thomas R. Mazur, Matthew C. Schmidt, Jessica Hilliard, Shahed Badiyan, Matthew B. Spraker, James A. Kavanaugh
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 29, Iss , Pp 100549- (2024)
Background and purpose: Spatially fractionated radiation therapy (SFRT) has demonstrated promising clinical response in treating large tumors with heterogeneous dose distributions. Lattice stereotactic body radiation therapy (SBRT) is an SFRT techniq
Externí odkaz:
https://doaj.org/article/93a1cb1160a8410b9074d06c2564bbe5
Autor:
Filipa Mota, Camilo A. Ruiz-Bedoya, Elizabeth W. Tucker, Daniel P. Holt, Patricia De Jesus, Martin A. Lodge, Clara Erice, Xueyi Chen, Melissa Bahr, Kelly Flavahan, John Kim, Mary Katherine Brosnan, Alvaro A. Ordonez, Charles A. Peloquin, Robert F. Dannals, Sanjay K. Jain
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-9 (2022)
Pretomanid has been approved for use in cases of multi-drug resistant pulmonary tuberculosis, yet the penetration of this antibiotic into other target tissues is not well established. Authors provide insight on pretomanid pharmacokinetics in the cent
Externí odkaz:
https://doaj.org/article/f0a782321c4e4e36aa37ab969660b2e2
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/3f38821f6eaf47988003b3c7cf76c889
Autor:
Janine T. Bossé, Yanwen Li, Leon G. Leanse, Liqing Zhou, Roy R. Chaudhuri, Sarah E. Peters, Jinhong Wang, Gareth A. Maglennon, Matthew T. G. Holden, Duncan J. Maskell, Alexander W. Tucker, Brendan W. Wren, Andrew N. Rycroft, Paul R. Langford, on behalf of the BRaDP1T consortium
Publikováno v:
Animal Diseases, Vol 1, Iss 1, Pp 1-13 (2021)
Abstract Comprehensive identification of conditionally essential genes requires efficient tools for generating high-density transposon libraries that, ideally, can be analysed using next-generation sequencing methods such as Transposon Directed Inser
Externí odkaz:
https://doaj.org/article/f094b55991ac4fa1b5e1c9c4b524d061
Autor:
Douglass W Tucker, Dhiraj J Pangal, Robin Du, Angad S Gogia, Ali Tafreshi, Jacob Ruzevick, Kyle T Hurth, Tim Triche, Alexander Micko, John D Carpten, Mark S Shiroishi, John D Carmichael, Suhn K Rhie, Gabriel Zada
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0284949 (2023)
IntroductionMany patients with growth hormone-secreting pituitary adenoma (GHPA) fail to achieve biochemical remission, warranting investigation into epigenetic and molecular signatures associated with tumorigenesis and hormonal secretion. Prior work
Externí odkaz:
https://doaj.org/article/95164e74ebdb43f7951533f9a05aaa54
Autor:
W. Tucker Shelton, S. Madison Thomas, Hunter R. Alexander, C. Evan Thomes, Daniel E. Conway, Adi D. Dubash
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-18 (2021)
Abstract Desmosomes have a central role in mediating extracellular adhesion between cells, but they also coordinate other biological processes such as proliferation, differentiation, apoptosis and migration. In particular, several lines of evidence h
Externí odkaz:
https://doaj.org/article/0d65ae5d5c894deaaddbec4c97f9ac2f