Zobrazeno 1 - 10
of 191
pro vyhledávání: '"W Todd, Cade"'
Autor:
Evariste Ntaganda, Regine Mugeni, Emmanuel Harerimana, Gedeon Ngoga, Symaque Dusabeyezu, Francois Uwinkindi, Jean N. Utumatwishima, Eugene Mutimura, Victor G. Davila-Roman, Kenneth Schechtman, Aurore Nishimwe, Laurence Twizeyimana, Angela L. Brown, W. Todd Cade, Marcus Bushaku, Lisa de Las Fuentes, Dominic Reeds, Marc Twagirumukiza
Publikováno v:
BMC Cardiovascular Disorders, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Hypertension remains the major risk factor for cardiovascular diseases (CVDs) worldwide with a prevalence and mortality in low- and middle-income countries (LMICs) among the highest. The early detection of hypertension risk factor
Externí odkaz:
https://doaj.org/article/9bda2afa4d09434da3e35edbfa5ac997
Autor:
Sarah Cooley, Brittany M Nelson, Alexander Rosenow, Elizabeth Westerhaus, W Todd Cade, Dominic N Reeds, Florin Vaida, Kevin E Yarasheski, Robert H Paul, Beau M Ances
Publikováno v:
JMIR Research Protocols, Vol 12, p e41421 (2023)
BackgroundWith the advent of antiretrovirals, people living with HIV are living near-normal lifespans. However, people living with HIV are at greater risk of experiencing cognitive impairment and reduced brain integrity despite well-controlled viremi
Externí odkaz:
https://doaj.org/article/ead27d5a0f604106934d8e5575246322
Autor:
Kathryn L. Bohnert, Grace Ditzenberger, Adam J. Bittel, Lisa de lasFuentes, Manuela Corti, Christina A. Pacak, Carolyn Taylor, Barry J. Byrne, Dominic N. Reeds, W. Todd Cade
Publikováno v:
JIMD Reports, Vol 62, Iss 1, Pp 74-84 (2021)
Abstract Background Muscle weakness and exercise intolerance contribute to reduced quality of life (QOL) in Barth syndrome (BTHS). Our group previously found that 12 weeks of resistance exercise training (RET) improved muscle strength, however, did n
Externí odkaz:
https://doaj.org/article/bda2cf0580534a32a6f3a6972555f1cf
Autor:
Jill M. Maples, Samantha F. Ehrlich, Nikki B. Zite, Kevin J. Pearson, W. Todd Cade, Courtney J. Riedinger, Maire M. Blankenship, Rachel A. Tinius
Publikováno v:
BMC Pregnancy and Childbirth, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Deviations from gestational weight gain (GWG) recommendations are associated with unfavorable maternal and neonatal outcomes. There is a need to understand how maternal substrate metabolism, independent of weight status, may contr
Externí odkaz:
https://doaj.org/article/e96574fc7c5c4681b3a35df8eb80770f
Autor:
Cole Hooley, Ana A. Baumann, Vincent Mutabazi, Angela Brown, Dominic Reeds, W. Todd Cade, Lisa de las Fuentes, Enola K. Proctor, Stephen Karengera, Kenneth Schecthman, Charles Goss, Pascal Launois, Victor G. Davila-Roman, Eugene Mutimura
Publikováno v:
Pilot and Feasibility Studies, Vol 6, Iss 1, Pp 1-8 (2020)
Abstract Background Hypertension (HTN) affects nearly 1 billion people globally and is a major cause of morbidity and mortality. In low- and middle-income countries (LMICs), HTN represents an unmet health care gap that can be addressed by strengtheni
Externí odkaz:
https://doaj.org/article/1cae77b35378448a859fea67c26daeaa
Autor:
Silveli Suzuki-Hatano, Madhurima Saha, Meghan S. Soustek, Peter B. Kang, Barry J. Byrne, W. Todd Cade, Christina A. Pacak
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 13, Iss , Pp 167-179 (2019)
Barth syndrome (BTHS) is a rare mitochondrial disease that causes severe cardiomyopathy and has no disease-modifying therapy. It is caused by recessive mutations in the gene tafazzin (TAZ), which encodes tafazzin—an acyltransferase that remodels th
Externí odkaz:
https://doaj.org/article/c10d127f83074a529b4127f37fe0df39
Autor:
Marcus Bushaku, Caleb Nyamwange, Arthur Kwena, Marc Twagirumukiza, Jean Nepo Utumatwishima, Regine Mugeni, Victor Davila-Roman, Aurore Nishimwe, Kenneth Schectman, W Todd Cade, Dominic Reeds, Eugene Mutimura
Publikováno v:
Journal of AIDS and HIV Treatment. 5:13-21
Background: Similar to other African countries, life expectancy of people living with HIV infection has improved due to access to antiretroviral therapy (ART) in Rwanda. However, both HIV infection and use of ART are associated with cardiovascular di
Autor:
W. Todd Cade, Kathryn L. Bohnert, Adam J. Bittel, Shaji J. Chacko, Bruce W. Patterson, Christina A. Pacak, Barry J. Byrne, Hilary J. Vernon, Dominic N. Reeds
Publikováno v:
Molecular Genetics and Metabolism Reports, Vol 25, Iss , Pp 100675- (2020)
Barth syndrome (BTHS) is a rare, X-linked cardiomyopathy that is characterized by abnormalities in glucose and lipid metabolism, with less known regarding amino acid metabolism. This pilot study characterized whole-body arginine kinetics and found lo
Externí odkaz:
https://doaj.org/article/925992a8f07247c387572895a3a12948
Autor:
Stephanie A. Schultz, Jennifer Byers, Tammie L. S. Benzinger, Dominic Reeds, Andrei G. Vlassenko, W. Todd Cade, Manu S. Goyal
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
Cardiorespiratory fitness (CRF) is routinely investigated in diverse populations, including in older adults of varying physical activity levels. Commonly performed maximal exercise testing protocols might be contraindicated and/or inadequate for olde
Externí odkaz:
https://doaj.org/article/fe3c9d45cdbe4e67906108db01d08d9a
Autor:
Shahryar Chowdhury, Lanier Jackson, Barry J. Byrne, Randall M. Bryant, W. Todd Cade, Tammy Lane Churchill, Julia Buchanan, Carolyn Taylor
Publikováno v:
Pediatric Cardiology. 43:1251-1263
Barth Syndrome (BTHS) is an X-linked mitochondrial cardioskeletal myopathy caused by defects in TAFAZZIN, a gene responsible for cardiolipin remodeling. Altered mitochondrial levels of cardiolipin lead to cardiomyopathy (CM), muscle weakness, exercis