Zobrazeno 1 - 10
of 16
pro vyhledávání: '"W T Cefalu"'
Autor:
B, Vandanmagsar, K R, Haynie, S E, Wicks, E M, Bermudez, T M, Mendoza, D, Ribnicky, W T, Cefalu, R L, Mynatt
Publikováno v:
Diabetes, obesitymetabolism. 16(8)
Bioactives of Artemisia dracunculus L. (termed PMI 5011) have been shown to improve insulin action by increasing insulin signalling in skeletal muscle. However, it was not known if PMI 5011's effects are retained during an inflammatory condition. We
It has been well documented that human adenovirus type 36 (Ad-36) is associated with obesity. However, the underlying molecular mechanism of Ad-36 inducing obesity remains unknown. We sought to investigate the effect of Ad-36 infection on Cidec, AMPK
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c535522666a1d4b34ea71db473117fb
https://europepmc.org/articles/PMC3962839/
https://europepmc.org/articles/PMC3962839/
Publikováno v:
Diabetes. 40:902-907
Publikováno v:
Clinical pharmacology and therapeutics. 81(5)
Type 2 diabetes, the most common form of diabetes, is characterized by abnormalities in hepatic glucose production, insulin resistance, and a progressive decline in beta-cell function over time. To treat effectively the individual with type 2 diabete
Autor:
W T, Cefalu
Publikováno v:
Annals of medicine. 33(9)
Subcutaneous insulin has been used to treat diabetes since the 1920s; however, despite a number of different formulations, intensive insulin therapy with multiple daily injections has not gained widespread clinical acceptance. Attempts to find effect
Publikováno v:
Laboratory animal science. 48(2)
Chronic hyperglycemia has been implicated in a number of diabetes mellitus-related conditions in the human population, including retinopathy, neuropathy, nephropathy, and vasculopathy. However, it has been difficult to evaluate the effect of long-ter
Publikováno v:
Laboratory animal science. 49(1)
One of the earliest pathologic changes of diabetes mellitus is increased nonenzymatic glycosylation (i.e., glycation) of proteins, which results in abnormal aggregation of collagen fibrils and production of superoxide radicals. These abnormalities ma
Publikováno v:
The Journal of clinical endocrinology and metabolism. 83(3)
We have previously shown that medroxyprogesterone acetate (MPA), either alone or combined with conjugated equine estrogens (CEE), significantly decreased insulin sensitivity (SI), compared with both untreated controls and those treated with CEE alone
Autor:
W T, Cefalu
Publikováno v:
Postgraduate medicine. 99(3)
Clinical goals in patients with non-insulin-dependent (type II) diabetes are to control glucose levels and prevent microvascular complications (eye, kidney, and nerve damage) while improving risk factors associated with cardiovascular disease (obesit
Publikováno v:
Laboratory animal science. 46(1)
Hyperglycemia associated with diabetes mellitus increases glycation of hemoglobin and serum proteins in human and nonhuman primates. It also has been documented that numerous other circulating proteins may be glycated. In this study we found that mos