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Anesthetic-induced Alteration of Ca2+Homeostasis in Neural Cells

Autor: Paul C. Brandt, John J. Franks, Thomas C. Vanaman, Piotr K. Janicki, Artur W. Wamil, W. T. Franks, Victoria E. Janson, Jean-Louis Horn

Publikováno v: Anesthesiology. 89:149-164

Background Many inhalation anesthetics at clinically relevant concentrations inhibit plasma membrane Ca2+-adenosine triphosphatase (PMCA) ion pumping in brain synaptic membranes and in cultured cells of neural origin. In this study, the authors inves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c713175a869c9fd34005b0bf37cc988
https://doi.org/10.1097/00000542-199807000-00022

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Halothane alters electrical activity and calcium dynamics in cultured mouse cortical, spinal cord, and dorsal root ganglion neurons

Autor: John J. Franks, W. T. Franks, Artur W. Wamil, Jean-Louis Horn, Piotr K. Janicki

Publikováno v: Neuroscience Letters. 216:93-96

Halothane inhibits neural plasma membrane Ca(2+)-ATPase, a pump that ejects Ca2+ from the cell after influx through voltage- or ligand-activated channels. Intracellular microelectrode recordings in mouse embryonic cortical and spinal cord neurons sho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b798fcf5855891d4894a677ee3cae1
https://doi.org/10.1016/0304-3940(96)13003-2

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Anesthetic-induced alteration of Ca2+ homeostasis in neural cells: a temperature-sensitive process that is enhanced by blockade of plasma membrane Ca2+-ATPase isoforms

Autor: J J, Franks, A W, Wamil, P K, Janicki, J L, Horn, W T, Franks, V E, Janson, T C, Vanaman, P C, Brandt

Publikováno v: Anesthesiology. 89(1)

Many inhalation anesthetics at clinically relevant concentrations inhibit plasma membrane Ca2+-adenosine triphosphatase (PMCA) ion pumping in brain synaptic membranes and in cultured cells of neural origin. In this study, the authors investigated the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bc583d97a162a79b01823821d574057f
https://pubmed.ncbi.nlm.nih.gov/9667305

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Decreased patient analgesic requirements after liver transplantation and associated neuropeptide levels

Autor: W. T. Franks, Striepe Vi, C. W. Pinson, K. L. Donovan, Stoica C, Piotr K. Janicki

Publikováno v: Transplantation. 63(10)

BACKGROUND Decreased morphine requirements have been reported after liver transplantation when compared with other types of major abdominal surgery. The aim of this study was to examine plasma concentrations of three neuropeptides involved in pain mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5989803f39baf7a09a86e28daa60acf0
https://pubmed.ncbi.nlm.nih.gov/9175805

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Liver transplantation is associated with increased met-enkephalin levels in the pig

Autor: C. W. Pinson, P. K. Janicki, K. L. Donovan, V. I. Striepe, W. T. Franks

Publikováno v: Acta anaesthesiologica Scandinavica. 40(9)

Background: It has been reported that less postoperative morphine is required following liver transplantation than is required following open cholecystectomy. This may be attributable to endogenous factors rather than to altered morphine pharmacokine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3fad5d1a6c7a6dbc122d02b4af67b3c
https://pubmed.ncbi.nlm.nih.gov/8933860

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