Zobrazeno 1 - 10 of 23 pro vyhledávání: '"W S Wold"'
1
Activation of intracellular proteases is an early event in TNF-induced apoptosis
Autor: C Voelkel-Johnson, A J Entingh, W S Wold, L R Gooding, S M Laster
Publikováno v: The Journal of Immunology. 154:1707-1716
The serine protease inhibitor tosyl-argenine methyl ester inhibits TNF-induced apoptosis, suggesting that proteolysis is necessary for this response. To test this hypothesis, we asked whether protein fragmentation occurs during the death of C3HA fibr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a84c9dfc76e9a6b7b77363db4821c057
https://doi.org/10.4049/jimmunol.154.4.1707
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2
The adenovirus E3-14.7K protein is a general inhibitor of tumor necrosis factor-mediated cytolysis
Autor: L R Gooding, I O Sofola, A E Tollefson, P Duerksen-Hughes, W S Wold
Publikováno v: The Journal of Immunology. 145:3080-3086
We have previously described a 14,700 m.w. protein (14.7K) encoded by the E3 region of adenovirus that prevents TNF-mediated cytolysis of adenovirus-infected C3HA mouse fibroblasts. In the studies described here we have extended our analysis of TNF c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6533aa925daa3a2775a08f6b0aab35ae
https://doi.org/10.4049/jimmunol.145.9.3080
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4
Characterization of the adenovirus E3 protein that down-regulates the epidermal growth factor receptor. Evidence for intermolecular disulfide bonding and plasma membrane localization
Autor: P, Hoffman, M B, Yaffe, B L, Hoffman, S, Yei, W S, Wold, C, Carlin
Publikováno v: The Journal of biological chemistry. 267(19)
We have characterized the biosynthesis and processing of a 91 amino acid hydrophobic integral membrane protein encoded by human group C adenoviruses which down-regulates the EGF receptor (Carlin, C. R., Tollefson, A. E., Brady, H. A., Hoffman, B. L.,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cb5257e91ac1f8a5ae02cb6ac46d72a4
https://pubmed.ncbi.nlm.nih.gov/1377684
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5
The E3-14.5K integral membrane protein of adenovirus that is required for down-regulation of the EGF receptor and for prevention of TNF cytolysis is O-glycosylated but not N-glycosylated
Autor: P, Krajcsi, A E, Tollefson, W S, Wold
Publikováno v: Virology. 188(2)
The adenovirus E3-14.5K protein is a cytoplasmic integral membrane protein that functions in concert with the E3-10.4K protein to down-regulate the epidermal growth factor receptor and to prevent tumor necrosis factor cytolysis in adenovirus-infected
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::236a4fe083d019105731c87d222ec04b
https://pubmed.ncbi.nlm.nih.gov/1533979
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6
Specificity of the mouse cytotoxic T lymphocyte response to adenovirus 5. E1A is immunodominant in H-2b, but not in H-2d or H-2k mice
Autor: F C, Rawle, B B, Knowles, R P, Ricciardi, V, Brahmacheri, P, Duerksen-Hughes, W S, Wold, L R, Gooding
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 146(11)
The Ag specificity and MHC restriction of the CTL response to adenovirus 5 (Ad5) in three strains of mice, C57BL/10 (H-2b), BALB/c (H-2d), and C3H/HeJ (H-2k), were tested. Polyclonal Ad5-specific CTL were prepared by priming mice in vivo with live Ad
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::452b113d4a64a0c24b4c2f62b3eb55e0
https://pubmed.ncbi.nlm.nih.gov/1827819
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7
The adenovirus E3-14.7K protein is a general inhibitor of tumor necrosis factor-mediated cytolysis
Autor: L R, Gooding, I O, Sofola, A E, Tollefson, P, Duerksen-Hughes, W S, Wold
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 145(9)
We have previously described a 14,700 m.w. protein (14.7K) encoded by the E3 region of adenovirus that prevents TNF-mediated cytolysis of adenovirus-infected C3HA mouse fibroblasts. In the studies described here we have extended our analysis of TNF c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5695a002cb15caf6b9c29a04a738d623
https://pubmed.ncbi.nlm.nih.gov/2145367
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9
Adenovirus E1A renders infected cells sensitive to cytolysis by tumor necrosis factor
Autor: P Duerksen-Hughes, W S Wold, L R Gooding
Publikováno v: The Journal of Immunology. 143:4193-4200
TNF is a multifunctional protein that is secreted by activated macrophages and is believed to have antiviral properties. We reported previously that certain murine fibroblasts infected with group C human adenoviruses become sensitive to cytolysis by
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::129093fff595a1e0b3710aeab983d5f9
https://doi.org/10.4049/jimmunol.143.12.4193
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10
Mouse anti-adenovirus cytotoxic T lymphocytes. Inhibition of lysis by E3 gp19K but not E3 14.7K
Autor: F C Rawle, A E Tollefson, W S Wold, L R Gooding
Publikováno v: The Journal of Immunology. 143:2031-2037
Early region E3 of adenovirus (Ad) appears to encode proteins involved in the interaction of the virus with the host immune system. The E3 region 19-kDa glycoprotein (gp19K) binds to class I MHC Ag in the endoplasmic reticulum and inhibits their tran
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e656d396d7132cbd15946e94a1eb6de7
https://doi.org/10.4049/jimmunol.143.6.2031
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