Zobrazeno 1 - 10
of 64
pro vyhledávání: '"W S, May"'
Publikováno v:
Leukemia. 15:515-522
Members of the Bcl2 family of proteins are important regulators of programmed cell death pathways with individual members that can suppress (eg Bcl2, Bcl-XL) or promote (eg Bax, Bad) apoptosis. While the mechanism(s) of Bcl2's anti-apoptotic function
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e29c25860a95deb991af884ae5e5c94
https://doi.org/10.1038/sj.leu.2402090
https://doi.org/10.1038/sj.leu.2402090
Publikováno v:
Research in Immunology. 146:351-361
Summary Bryostatin-1 - but not bryostatin-13 - a macrocyclic lactone isolated from the marine bryozoan Bugula neritina , triggered human polymorphonuclear neutrophil (PMN) and monocyte release of reactive oxygen radicals, as measured by the generatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c36d66012b01579a0999d5bff563c5b3
https://doi.org/10.1016/0923-2494(96)81039-x
https://doi.org/10.1016/0923-2494(96)81039-x
Publikováno v:
Blood. 85:3040-3047
CD34 is expressed on human and murine hematopoietic stem and progenitor cells and its clinical usefulness for isolation of stem/progenitor cells has been well established. Although expression of CD34 is regulated in a developmental stage-specific man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8681b644ab6f1f2bf16d8ddd6ba5506c
https://doi.org/10.1182/blood.v85.11.3040.bloodjournal85113040
https://doi.org/10.1182/blood.v85.11.3040.bloodjournal85113040
Publikováno v:
Journal of Biological Chemistry. 269:26865-26870
Using murine myeloid factor-dependent FDC-P1/ER cells, we demonstrate that the hematopoietic growth factors interleukin-3 and erythropoietin and bryostatin-1, a macrocyclic lactone natural product and potent activator of protein kinase C (PKC), suppr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0db86b2dca4ec8431b77779e608eff47
https://doi.org/10.1016/s0021-9258(18)47099-8
https://doi.org/10.1016/s0021-9258(18)47099-8
Publikováno v:
Blood. 84:691-701
CD34 is expressed on human hematopoietic stem and progenitor cells, and its clinical usefulness for the purification of stem cells has been well established. However, a similar pattern of expression for murine CD34 (mCD34) has not yet been determined
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7155d1dace073c3e846ba54b1597b15
https://doi.org/10.1182/blood.v84.3.691.691
https://doi.org/10.1182/blood.v84.3.691.691
Autor:
M.P. Carroll, W S May
Publikováno v:
Journal of Biological Chemistry. 269:1249-1256
We have previously found that Raf-1, which is activated by hematopoietic growth factors in association with phosphorylation, is required for hematopoietic cell proliferation. Recently, 12-O-tetradecanoylphorbol 13-acetate has been found to mediate Ra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::619e8ebaaf47b8f835224b47df0cca44
https://doi.org/10.1016/s0021-9258(17)42250-2
https://doi.org/10.1016/s0021-9258(17)42250-2
Publikováno v:
Proceedings of the National Academy of Sciences. 90:4674-4678
Human immunodeficiency virus (HIV-1) infection is followed by a period of latency or a low-level-persistent (LLP) state that results in an asymptomatic infection of the host. Productive viral expression may be triggered by a variety of activators inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7993f1c5babc17e590d4ac38e1c75c38
https://doi.org/10.1073/pnas.90.10.4674
https://doi.org/10.1073/pnas.90.10.4674
Publikováno v:
Journal of Biological Chemistry. 267:17540-17546
CD34 is a transmembrane sialoglycoprotein expressed by early hematopoietic progenitor cells as well as endothelial cells. Previously we found that CD34 is rapidly and stoichiometrically phosphorylated by activated protein kinase C (PKC) (Fackler, M.J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d14a6aeb9fa132c4dca06f61713c852
https://doi.org/10.1016/s0021-9258(19)37076-0
https://doi.org/10.1016/s0021-9258(19)37076-0
Publikováno v:
The Journal of Immunology. 147:3474-3481
T lymphocyte activation is initiated as a result of the interaction between the TCR complex and Ag as seen in the framework of a membrane-bound MHC molecule. Receptor stimulation results in a rise in free intracellular Ca2+ and the activation of prot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62aefc5e141ec5cc0dfab11f89be12d4
https://doi.org/10.4049/jimmunol.147.10.3474
https://doi.org/10.4049/jimmunol.147.10.3474
Publikováno v:
Journal of Biological Chemistry. 266:14964-14969
Erythropoietin mediates the rapid phosphorylation of Raf-1 in the murine cell lines HCD-57 and FDC-P1/ER, which proliferate in response to this cytokine. Phosphorylation occurs at both serine and tyrosine residues and as such is similar to the Raf-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b39c4e74f3b8633d984e74d3ef03dbd
https://doi.org/10.1016/s0021-9258(18)98572-8
https://doi.org/10.1016/s0021-9258(18)98572-8