Zobrazeno 1 - 10
of 120
pro vyhledávání: '"W Robb MacLellan"'
Autor:
Zhenhe Zhang, Miles Freeman, Yiqiang Zhang, Danny El-Nachef, George Davenport, Allison Williams, W Robb MacLellan
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0281610 (2023)
AimsAccumulating data demonstrates that new adult cardiomyocytes (CMs) are generated throughout life from pre-existing CMs, although the absolute magnitude of CM self-renewal is very low. Modifying epigenetic histone modifications or activating the H
Externí odkaz:
https://doaj.org/article/a8a9f94f16b74a2c9917c153f39f982d
Autor:
Patima Sdek, Kyohei Oyama, Ekaterini Angelis, Shing S Chan, Katja Schenke-Layland, W Robb MacLellan
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e58319 (2013)
Heterochromatin protein 1 (HP1) is an essential heterochromatin-associated protein typically involved in the epigenetic regulation of gene silencing. However, recent reports have demonstrated that HP1 can also activate gene expression in certain cont
Externí odkaz:
https://doaj.org/article/47f58ef78998490f86f206586951a600
Autor:
Ali Nsair, Katja Schenke-Layland, Ben Van Handel, Denis Evseenko, Michael Kahn, Peng Zhao, Joseph Mendelis, Sanaz Heydarkhan, Obina Awaji, Miriam Vottler, Susanne Geist, Jennifer Chyu, Nuria Gago-Lopez, Gay M Crooks, Kathrin Plath, Josh Goldhaber, Hanna K A Mikkola, W Robb MacLellan
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e45603 (2012)
Cardiovascular progenitor cells (CPCs) have been identified within the developing mouse heart and differentiating pluripotent stem cells by intracellular transcription factors Nkx2.5 and Islet 1 (Isl1). Study of endogenous and induced pluripotent ste
Externí odkaz:
https://doaj.org/article/fde20397c85f45dd9483e83406869170
Autor:
Kyohei Oyama, Danny El-Nachef, Chen Fang, Hidemi Kajimoto, Jeremy P. Brown, Prim B. Singh, W. Robb MacLellan
Publikováno v:
Epigenetics & Chromatin, Vol 11, Iss 1, Pp 1-15 (2018)
Abstract Background Heterochromatin, which is formed when tri-methyl lysine 9 of histone H3 (H3K9me3) is bound by heterochromatin 1 proteins (HP1s), plays an important role in differentiation and senescence by silencing cell cycle genes. Cardiac myoc
Externí odkaz:
https://doaj.org/article/a8976ee3773e4a23bd563d67ccc34511
Autor:
Silvia Marchiano, Kenta Nakamura, Hans Reinecke, Lauren Neidig, Jordan Klaiman, Xiulan Yang, Leslie Blakely, Faith Kalucki, Sarah Dupras, Bjorn C. Knollmann, Steven Kattman, Nathan Sniadecki, Scott Thies, W. Robb MacLellan, Alessandro Bertero, Charles Murry
Publikováno v:
Heart Rhythm. 20:S270
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d3e6681737a93a21889b0554f4d8c1b
https://doi.org/10.1016/j.hrthm.2023.03.730
https://doi.org/10.1016/j.hrthm.2023.03.730
Publikováno v:
International journal of cardiology and cardiovascular diseases. 1(1)
Histological analysis of fluorescently labeled tissues has been a critical tool to understand molecular organization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d91cb4ac6334688e4929c75c1f80276
https://pubmed.ncbi.nlm.nih.gov/35243481
https://pubmed.ncbi.nlm.nih.gov/35243481
Autor:
Alessandro Bertero, Rong Tian, Kevin C. Cain, R. Scott Thies, Anu Jayabalu, Melissa R. Robinson, W. Robb MacLellan, Danny El-Nachef, Dale Whittington, Daisy S. Nakamura, Faith A. Kalucki, Hiroshi Tsuchida, Lauren E. Neidig, Gerhard J. Weber, Charles E. Murry, Silvia Marchianò, Lil Pabon, Akiko Futakuchi-Tsuchida, Bjorn C. Knollmann, Xiulan Yang, Steven Kattman, Hans Reinecke, Sarah K. Dupras, Kenta Nakamura
Publikováno v:
Stem Cell Reports
Summary Heart failure remains a significant cause of morbidity and mortality following myocardial infarction. Cardiac remuscularization with transplantation of human pluripotent stem cell-derived cardiomyocytes is a promising preclinical therapy to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1189e00de9d9819aacf1d2936c5a883
http://hdl.handle.net/2318/1804571
http://hdl.handle.net/2318/1804571
Autor:
W. Robb MacLellan, Charles E. Murry
Publikováno v:
Science (New York, N.Y.). 367(6480)
After 20 years of research, pluripotent stem cells move to the fore to treat heart disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f84004f60522a60e36cc3864288004
https://pubmed.ncbi.nlm.nih.gov/32079761
https://pubmed.ncbi.nlm.nih.gov/32079761
Autor:
Kenta Nakamura, W. Robb MacLellan
Publikováno v:
Heart Failure: a Companion to Braunwald's Heart Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::162a0c68e1051e979d8c166526dd1bb7
https://doi.org/10.1016/b978-0-323-60987-6.00041-7
https://doi.org/10.1016/b978-0-323-60987-6.00041-7
Autor:
E. Dale Abel, Luigi Adamo, Shah R. Ali, Larry A. Allen, George L. Bakris, Gerald S. Bloomfield, Robert O. Bonow, Biykem Bozkurt, Michael R. Bristow, Angela L. Brown, Heiko Bugger, John C. Burnett, Javed Butler, John D. Carroll, Adam Castaño, Anna Marie Chang, Jay N. Cohn, Wilson S. Colucci, Louis J. Dell’Italia, Anita Deswal, Adam D. DeVore, Abhinav Diwan, Hilary M. DuBrock, Shannon M. Dunlay, Nina Dzhoyashvili, Gregory A. Ewald, Justin A. Ezekowitz, James C. Fang, Savitri Fedson, Matthew J. Feinstein, G. Michael Felker, John D. Ferguson, Victor A. Ferrari, Carlos M. Ferrario, James D. Flaherty, John S. Floras, Viorel G. Florea, Hanna K. Gaggin, Barry Greenberg, Joshua M. Hare, Adrian F. Hernandez, Joseph A. Hill, Nasrien E. Ibrahim, James L. Januzzi, Susan M. Joseph, Daniel P. Judge, Andrew M. Kahn, Andreas P. Kalogeropoulos, David A. Kass, John Keaney, Ahsan A. Khan, Paul J. Kim, Jon A. Kobashigawa, Evan P. Kransdorf, Eric V. Krieger, Nicholas T. Lam, Daniel J. Lenihan, Gregory Y.H. Lip, Chris T. Longenecker, W. Robb MacLellan, Douglas L. Mann, Ali J. Marian, Daniel D. Matlock, Mathew S. Maurer, Dennis M. McNamara, Robert J. Mentz, Marco Metra, Carmelo A. Milano, Arunima Misra, Joshua D. Mitchell, Alan R. Morrison, Adam Nabeebaccus, Kenta Nakamura, Jose Nativi-Nicolau, Doan T.M. Ngo, Kelsie E. Oatmen, Peter S. Pang, Lampros Papadimitriou, Walter J. Paulus, Tamar S. Polonsky, J. David Port, Florian Rader, Loheetha Ragupathi, Margaret M. Redfield, Michael W. Rich, Joseph G. Rogers, John J. Ryan, Hesham A. Sadek, Can Martin Sag, Ashley A. Sapp, Douglas B. Sawyer, P. Christian Schulze, Ajay M. Shah, Eduard Shantsila, Jagmeet P. Singh, Albert J. Sinusas, Karen Sliwa, Francis G. Spinale, Simon Stewart, Carmen Sucharov, Martin St. John Sutton, Aaron L. Sverdlov, Michael J. Toth, Anne Marie Valente, Loek van Heerebeek, Jasmina Varagic, Ronald G. Victor, Ian Webb, Adam R. Wende, David Whellan, Dominik M. Wiktor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dda3f3f2170fa669e86863d27bc94b33
https://doi.org/10.1016/b978-0-323-60987-6.01002-4
https://doi.org/10.1016/b978-0-323-60987-6.01002-4