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Akademický článek

covRNA: discovering covariate associations in large-scale gene expression data

Autor: Lara Urban, Christian W. Remmele, Marcus Dittrich, Roland F. Schwarz, Tobias Müller

Publikováno v: BMC Research Notes, Vol 13, Iss 1, Pp 1-5 (2020)

Abstract Objective The biological interpretation of gene expression measurements is a challenging task. While ordination methods are routinely used to identify clusters of samples or co-expressed genes, these methods do not take sample or gene annota

Externí odkaz: https://doaj.org/article/9d39ab58f6984b20b48a98729ab8e493

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What is walking? a systematic review and meta-ethnography

Autor: L Delgado Ortiz, A Polhemus, A Keogh, N Sutton, W Remmele, C Hansen, F Kluge, B Sharrack, C Becker, T Troosters, W Maetzler, L Rochester, A Frei, M Puhan, J Garcia-Aymerich

Publikováno v: 05.02 - Monitoring airway disease.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8485f453644ebc36f76e1214b7d31fa
https://doi.org/10.1183/13993003.congress-2022.377

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Akademický článek

Staphylococcus aureus Exploits a Non-ribosomal Cyclic Dipeptide to Modulate Survival within Epithelial Cells and Phagocytes.

Autor: Sebastian Blättner, Sudip Das, Kerstin Paprotka, Ursula Eilers, Markus Krischke, Dorothee Kretschmer, Christian W Remmele, Marcus Dittrich, Tobias Müller, Christina Schuelein-Voelk, Tobias Hertlein, Martin J Mueller, Bruno Huettel, Richard Reinhardt, Knut Ohlsen, Thomas Rudel, Martin J Fraunholz

Publikováno v: PLoS Pathogens, Vol 12, Iss 9, p e1005857 (2016)

Community-acquired (CA) Staphylococcus aureus cause various diseases even in healthy individuals. Enhanced virulence of CA-strains is partly attributed to increased production of toxins such as phenol-soluble modulins (PSM). The pathogen is internali

Externí odkaz: https://doaj.org/article/9698c7667459459cb09fc76121b08fa8

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Akademický článek

Integrated inference and evaluation of host-fungi interaction networks

Autor: Christian W. Remmele, Christian eLuther, Johannes eBalkenhol, Thomas eDandekar, Tobias eMueller, Marcus T. Dittrich

Publikováno v: Frontiers in Microbiology, Vol 6 (2015)

Fungal microorganisms frequently lead to life-threatening infections. Within this group of pathogens, the commensal Candida albicans and the filamentous fungus Aspergillus fumigatus are by far the most important causes of invasive mycoses in Europe.

Externí odkaz: https://doaj.org/article/f2d82d372b6b4f47b6cd88096300f8fb

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Cell Type and Species-specific Patterns in Neuronal and Non-neuronal Methylomes of Human and Chimpanzee Cortices

Autor: Nady El Hajj, Thomas Haaf, Carsten P Ade, Julia Böck, Eberhard Schneider, Ronald E. Bontrop, Armin Giese, Ivanela Kondova, Marcus Dittrich, Christian W. Remmele, Tobias Müller, Stephan P. Persengiev, Theo F. J. Kraus

Publikováno v: Cerebral Cortex (New York, NY)

Epigenetic changes have likely contributed to the large size and enhanced cognitive abilities of the human brain which evolved within the last 2 million years after the human–chimpanzee split. Using reduced representation bisulfite sequencing, we h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647a441ad8eb7fc9cb082dfb42f97709
https://doi.org/10.1093/cercor/bhy180

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Development of Long Noncoding RNA-Based Strategies to Modulate Tissue Vascularization

Autor: K. Breckwoldt, Christian W. Remmele, Annette Just, Jan Fiedler, Angelika Pfanne, Marcus Dittrich, Thomas Eschenhagen, Dorothee Hartmann, Ke Xiao, Thomas Thum, Robert Geffers, Tobias Müller, Arne Hansen, Thomas Dandekar, Meik Kunz

Publikováno v: Journal of the American College of Cardiology. 66:2005-2015

BackgroundLong noncoding ribonucleic acids (lncRNAs) are a subclass of regulatory noncoding ribonucleic acids for which expression and function in human endothelial cells and angiogenic processes is not well studied.ObjectivesThe authors discovered h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97d4f7294c254110939447af5dee1d6a
https://doi.org/10.1016/j.jacc.2015.07.081

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Naturally mutations in a Staphylococcus aureus virulence regulator attenuate cytotoxicity but permit bacteremia and abscess formation

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America

Staphylococcus aureus is a major bacterial pathogen, which causes severe blood and tissue infections that frequently emerge by autoinfection with asymptomatically carried nose and skin populations. However, recent studies report that bloodstream isol

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2d95567f76c96baebf7e631cf36e60a
https://doi.org/10.1073/pnas.1520255113