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Autor:
F.H.J. Gmelig Meyling, J. H. Van Es, R. H. W. M. Derksen, Ton Logtenberg, H. Aanstoot, W R van de Akker
Publikováno v:
The Journal of Experimental Medicine
The processes that govern the generation of pathogenic anti-DNA autoantibodies in human systemic lupus erythematosus (SLE) are largely unknown. Autoantibodies may arise as a consequence of polyclonal B cell activation and/or antigen-driven B cell act