Zobrazeno 1 - 10
of 10
pro vyhledávání: '"W R, Shehee"'
Autor:
Anna K. Bassil, F P Maurio, C M Taylor, Gareth J. Sanger, N B Dass, C W Crumbley, Gary B.T. Moore, A K John, W R Shehee
Publikováno v:
Neurogastroenterology & Motility. 19:66-74
The G protein-coupled receptors, GPR41 and GPR43, are activated by short-chain fatty acids (SCFAs), with distinct rank order potencies. This study investigated the possibility that SCFAs modulate intestinal motility via these receptors. Luminal SCFA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3df3ef67ff73f942b2e3ebab59f80935
https://doi.org/10.1111/j.1365-2982.2006.00853.x
https://doi.org/10.1111/j.1365-2982.2006.00853.x
Autor:
W R Shehee, T M Townes, J B Whitney rd, A Leder, Jada Lewis, R A Popp, C Paszty, Oliver Smithies, E M Rubin
Publikováno v:
Biochemical Genetics. 36:65-77
The hematology of the laboratory mouse has been well characterized. Normal genetic differences at the alpha- and beta-globin gene loci serve as useful markers for a wide variety of types of experimental studies. There are a number of naturally occurr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::35a2c86dc6fe79d84008e3b55b9913f9
https://doi.org/10.1023/a:1018752219810
https://doi.org/10.1023/a:1018752219810
Publikováno v:
Molecular and Cellular Biology. 14:6936-6943
We describe a two-step strategy to alter any mouse locus repeatedly and efficiently by direct positive selection. Using conventional targeting for the first step, a functional neo gene and a nonfunctional HPRT minigene (the "socket") are introduced i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe590c9355d3872238151ae0cb8c74f
https://doi.org/10.1128/mcb.14.10.6936-6943.1994
https://doi.org/10.1128/mcb.14.10.6936-6943.1994
Autor:
Oliver Smithies, T Papayannopoulou, Edward G. Shesely, W R Shehee, Hyung Suk Kim, B W Popovich
Publikováno v:
Proceedings of the National Academy of Sciences. 88:4294-4298
As a step toward using gene targeting for gene therapy, we have corrected a human beta S-globin gene to the normal beta A allele by homologous recombination in the mouse-human hybrid cell line BSM. BSM is derived from a mouse erythroleukemia cell lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d29cc4a1fb5f0ef49de9ef859fb7168
https://doi.org/10.1073/pnas.88.10.4294
https://doi.org/10.1073/pnas.88.10.4294
Autor:
M W, Roe, J F, Worley, A A, Mittal, A, Kuznetsov, S, DasGupta, R J, Mertz, S M, Witherspoon, N, Blair, M E, Lancaster, M S, McIntyre, W R, Shehee, I D, Dukes, L H, Philipson
Publikováno v:
The Journal of biological chemistry. 271(50)
Voltage-dependent delayed rectifier K+ channels regulate aspects of both stimulus-secretion and excitation-contraction coupling, but assigning specific roles to these channels has proved problematic. Using transgenically derived insulinoma cells (bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::723326b060f01dedebfff1b11c2ad0bc
https://pubmed.ncbi.nlm.nih.gov/8943282
https://pubmed.ncbi.nlm.nih.gov/8943282
Publikováno v:
Gene. 103(2)
We have investigated problems encountered when using the polymerase chain reaction (PCR) to detect recombinants in gene targeting experiments in which homologous recombination occurs between incoming DNA and an endogenous target sequence. The targeti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8975adb542d72423e2db3a9e5d60d9e4
https://pubmed.ncbi.nlm.nih.gov/1889748
https://pubmed.ncbi.nlm.nih.gov/1889748
Autor:
Marshall H. Edgell, Stephen C. Hardies, Clyde A. Hutchison, Mary B. Comer, W R Shehee, Daniel D. Loeb, Richard W. Padgett
The complete nucleotide sequence of a 6,851-base pair (bp) member of the L1Md repetitive family from a selected random isolate of the BALB/c mouse genome is reported here. Five kilobases of the element contains two overlapping reading frames of 1,137
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39d7f6d7b37198e7438bcf90dfa5a038
Autor:
Steven A. Schichman, C.J Davies, Diana M. Severynse, N. C. Casavant, F.W Weyter, Frank H. Burton, Clyde A. Hutchison, Marshall H. Edgell, P Cole, G.B Wisely, W R Shehee, Royal A. McGraw, Nils B. Adey, Charles F. Voliva, Daniel D. Loeb
Publikováno v:
Journal of molecular biology. 205(1)
The nucleotide sequence of 55,856 base-pairs containing all seven beta-globin homologous structures from chromosome 7 of the BALB/c mouse is reported. This sequence links together previously published sequences of the beta-globin genes, pseudogenes a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4322ecdbdf5cdc8202d99e232f227248
https://pubmed.ncbi.nlm.nih.gov/2926808
https://pubmed.ncbi.nlm.nih.gov/2926808
Publikováno v:
Oncodevelopmental biology and medicine : the journal of the International Society for Oncodevelopmental Biology and Medicine. 3(5-6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f6dcd7da374819db309c879112b31fa
https://pubmed.ncbi.nlm.nih.gov/7145724
https://pubmed.ncbi.nlm.nih.gov/7145724
Autor:
M H, Edgell, S C, Hardies, D D, Loeb, W R, Shehee, R W, Padgett, F H, Burton, M B, Comer, N C, Casavant, F D, Funk, C A, Hutchison
Publikováno v:
Progress in clinical and biological research. 251
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::09e4fda3d80deb36da9727fae01d82ad
https://pubmed.ncbi.nlm.nih.gov/2829228
https://pubmed.ncbi.nlm.nih.gov/2829228