Zobrazeno 1 - 8 of 8 pro vyhledávání: '"W R, Mancini"'
1
Sensitization of 1,3-bis(2-chloroethyl)-1-nitrosourea and cisplatin cytotoxicity by 5-bromo-2'-deoxyuridine in human glioma
Autor: W R, Mancini, E R, Glaze, P L, Stetson, H S, Greenberg
Publikováno v: The Journal of pharmacology and experimental therapeutics. 289(3)
5-Bromo-2'-deoxyuridine (BrdUrd) was found to increase the cytotoxicity induced by 1,3-bis(2-chloroethyl)-1-nitrosourea (BCNU) and cisplatin in human glioma cells. At a fixed concentration of BrdUrd and BCNU, the greatest cell loss was observed in ex
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5b108895c4cbac3555d0f3b36e0cfdad
https://pubmed.ncbi.nlm.nih.gov/10336533
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2
Variability of 5-bromo-2'-deoxyuridine incorporation into DNA of human glioma cell lines and modulation with fluoropyrimidines
Autor: W R, Mancini, P L, Stetson, T S, Lawrence, J G, Wagner, H S, Greenberg, W D, Ensminger
Publikováno v: Cancer research. 51(3)
Human glioma-derived cell lines were found to vary in their ability to incorporate the radiosensitizer 5-bromo-2'-deoxyuridine (BrdUrd) into DNA after one cell doubling. The U-251 cell line was the best incorporator of BrdUrd, whereas U-118 and D-54
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bbce58636611c24b034bc22bfa0e2634
https://pubmed.ncbi.nlm.nih.gov/1824826
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3
The relationship between incorporation of E-5-(2-Bromovinyl)-2'-deoxyuridine into herpes simplex virus type 1 DNA with virus infectivity and DNA integrity
Autor: W R Mancini, William H. Prusoff, E. De Clercq
Publikováno v: Journal of Biological Chemistry. 258:792-795
E-5-(2-Bromovinyl)-2'-deoxyuridine (BrvdUrd) produced a dose-dependent shift in the density of herpes simplex virus type 1 (HSV-1) DNA at concentrations which yielded potent inhibition of virus replication in cultured Vero cells. Although the density
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6daf21e4883dc95df85172f9509d122
https://doi.org/10.1016/s0021-9258(18)33118-1
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4
Isoquinoline and peripheral-type benzodiazepine binding in gliomas: implications for diagnostic imaging
Autor: J M, Olson, L, Junck, A B, Young, J B, Penney, W R, Mancini
Publikováno v: Cancer research. 48(20)
Binding of the isoquinoline PK 11195 and of the benzodiazepines Ro5-4864 and flunitrazepam was compared in glioma cells and tissues. In human and rat glioma cell cultures [3H]PK 11195 bound with higher affinity (Kd = 14.01 and 15.76 nM, respectively)
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fcaeee44635bafadbf5f6167fb026e05
https://pubmed.ncbi.nlm.nih.gov/3262414
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8
The relationship between incorporation of E-5-(2-Bromovinyl)-2'-deoxyuridine into herpes simplex virus type 1 DNA with virus infectivity and DNA integrity
Autor: W R, Mancini, E, De Clercq, W H, Prusoff
Publikováno v: The Journal of biological chemistry. 258(2)
E-5-(2-Bromovinyl)-2'-deoxyuridine (BrvdUrd) produced a dose-dependent shift in the density of herpes simplex virus type 1 (HSV-1) DNA at concentrations which yielded potent inhibition of virus replication in cultured Vero cells. Although the density
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e4976908295b07f13eff955dbe7a974f
https://pubmed.ncbi.nlm.nih.gov/6296080
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