Zobrazeno 1 - 10
of 19
pro vyhledávání: '"W R, Hewitt"'
Autor:
S C, Chen, W R, Hewitt, F D, Watanabe, S, Eguchi, E, Kahaku, Y, Middleton, J, Rozga, A A, Demetriou
Publikováno v:
The International journal of artificial organs. 19(11)
The only clinically proven effective treatment of fulminant hepatic failure (FHF) is orthotopic liver transplant (OLT). However, many patients die before an organ becomes available. Thus, there is a need for development of an extracorporeal liver sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2278fac5915ac482a86d6634339066c9
https://pubmed.ncbi.nlm.nih.gov/8970834
https://pubmed.ncbi.nlm.nih.gov/8970834
Autor:
S, Eguchi, J, Rozga, L T, Lebow, S C, Chen, C C, Wang, R, Rosenthal, L, Fogli, W R, Hewitt, Y, Middleton, A A, Demetriou
Publikováno v:
Transplantation. 62(5)
Numerous studies have reported successful allotransplantation of hepatocytes. However, none have shown long-term correction of a liver-related metabolic defect. In this study, we used a method of regional hepatocyte transplantation and subsequent ind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::288445ea92699cc8e8897a1ab479f6ff
https://pubmed.ncbi.nlm.nih.gov/8830820
https://pubmed.ncbi.nlm.nih.gov/8830820
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 199(3)
Preparation and incubation of renal cortical slices from adult, female, New Zealand white rabbit depleted tissue citrate concentration. Acetate (10.0 mM) in the incubation significantly increased slice citrate concentration and p-aminohippurate (PAH)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb0ad44c9613a6bfb894ac3e79d163c7
https://pubmed.ncbi.nlm.nih.gov/11338
https://pubmed.ncbi.nlm.nih.gov/11338
Publikováno v:
Journal of toxicology and environmental health. 9(2)
Acute oral pretreatment of rats with isopropanol or acetone results in a dose-related potentiation of CCl4 hepatotoxicity. Minimally effective doses (MED) and noneffective doses (NED) of both agents were estimated to be 0.25 and 0.10 ml/kg, respectiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5ecad50870c21ce91587fc90cbba6be5
https://pubmed.ncbi.nlm.nih.gov/6281449
https://pubmed.ncbi.nlm.nih.gov/6281449
Publikováno v:
Federation proceedings. 39(13)
A variety of chemicals potentiate haloalkane-induced liver injury, but structure-activity relationships are not apparent. Recent studies have shown that one structural determinant, a carbonyl moiety, is common to several potentiating agents. Thus fiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::697875ef98c92c53040036cdb729cd52
https://pubmed.ncbi.nlm.nih.gov/7428955
https://pubmed.ncbi.nlm.nih.gov/7428955
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 3(2)
Chlordecone (10 mg/kg, sc in corn oil) was administered to mature female rabbits once daily for five days. Analysis of oviductal fluid collected from these rabbits over the course of this experiment confirmed the presence of chlordecone. It is reason
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::8529fb4887b7f29ed8106723547cae03
https://pubmed.ncbi.nlm.nih.gov/6192033
https://pubmed.ncbi.nlm.nih.gov/6192033
Autor:
W R, Hewitt, J B, Hook
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 207(3)
The renal organic anion transport system has been linked to the selective extraction of nonesterified fatty acids (NEFA) from arterial blood. Consequently, p-aminohippurate (PAH) and palmitate may compete for a common intracellular binding site or ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c9228c5d033bb67cc2f76196529a0d85
https://pubmed.ncbi.nlm.nih.gov/731428
https://pubmed.ncbi.nlm.nih.gov/731428
Publikováno v:
Toxicology and applied pharmacology. 83(2)
These experiments were designed to elucidate the initiating biochemical events mediating cephaloridine (CPH) nephrotoxicity. Renal cortical slices from naive male Fischer-344 rats were incubated at 37°C in a phosphate- or bicarbonate-buffered medium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f503b60798d25ba4840cee3a7c44e02
https://pubmed.ncbi.nlm.nih.gov/3961814
https://pubmed.ncbi.nlm.nih.gov/3961814
Publikováno v:
Proceedings of the Western Pharmacology Society. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b55b0f6a51ace2703f2c3cdc40d05eed
https://pubmed.ncbi.nlm.nih.gov/1178692
https://pubmed.ncbi.nlm.nih.gov/1178692
Autor:
W R, Hewitt, E M, Brown
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 4(6)
Recent studies have indicated that (1) ketonic solvents and ketogenic chemicals can potentiate the nephrotoxic and hepatotoxic effects of one or more halogenated hydrocarbons; and (2) the relative ability of ketones to potentiate the liver injury pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7adb3888927bb7d38ee95b20d2ee4da8
https://pubmed.ncbi.nlm.nih.gov/6394413
https://pubmed.ncbi.nlm.nih.gov/6394413