Zobrazeno 1 - 6
of 6
pro vyhledávání: '"W R, Galpern"'
Publikováno v:
Central Nervous System Diseases ISBN: 9781617371523
Parkinson’s disease (PD) is a progressive neurodegenerative disease characterized clinically by bradykinesia, rigidity, and resting tremor. The motor abnormalities are associated with a specific loss of dopamine (DA) neurons in the substantia nigra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbd75912c68e9f8d9d145182a353ed9d
https://doi.org/10.1007/978-1-59259-691-1_11
https://doi.org/10.1007/978-1-59259-691-1_11
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 261(1)
Chronic administration of benzodiazepine active at the tau-aminobutyric acidA receptor ("central" benzodiazepine sites) is associated with behavioral tolerance and receptor downregulation. Recent reports indicate possible interactions between central
Publikováno v:
Biochemical pharmacology.
Clinical studies suggest that carbamazepine may attenuate effects of alprazolam discontinuation. Since discontinuation of chronic alprazolam in a mouse model is associated with behavioral alterations and upregulation at the gamma-aminobutyric acidA (
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 258(1)
Treatment with benzodiazepine agonists is associated with the development of behavioral tolerance and receptor downregulation, whereas antagonist administration has been reported to lead to increased activity and receptor upregulation. To determine t
Publikováno v:
Molecular pharmacology. 39(2)
Interleukin-1 (IL-1), a cytokine involved in the acute phase reaction to injury and infection, has multiple effects in the central nervous system, including induction of fever and sleep and the release of several neuropeptides. We evaluated effects o
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 254(1)
Chronic benzodiazepine administration has been reported to lead to behavioral tolerance and, in some cases, downregulation of gamma-aminobutyric acid A (GABAA)-receptor binding and function. So-called "partial agonist" benzodiazepines appear to cause