Zobrazeno 1 - 6
of 6
pro vyhledávání: '"W R, Fredericks"'
Publikováno v:
Radio Science. 14:345-348
Cerebrovascular permeability to 14C-sucrose was measured independently of cerebral blood flow in the rat, following unilateral osmotic opening of the blood-brain barrier by hypertonic arabinose solution. An increase in regional permeability to 14C-su
Publikováno v:
Surgical neurology. 12(4)
Osmotic opening of the blood-brain barrier in the rat, by intracarotid infusion of 1.6 molal (m) arabinose solution, increases cerebrovascular permeability to 3H-methotrexate by a factor of about seven. PA (product of permeability and capillary surfa
Publikováno v:
Infection and immunity. 11(2)
Axial filaments were isolated and purified from Reiter treponemes after detergent solubilization of the cells" outer envelope. The axial filaments were separated from the spirochetal cells by shearing, purified by density gradient centrifugation, and
Publikováno v:
Cancer research. 45(3)
Right brain regions of anesthetized rats were loaded with [3,5,7-3H]methotrexate ([3H]MTX) or with [14C]sucrose by infusing the tracers into the right carotid artery, after the blood-brain barrier had been opened by right carotid infusion of a hypert
Autor:
Stanley I. Rapoport, W R Fredericks
Publikováno v:
Stroke. 19(2)
Unilateral reversible osmotic opening of the blood-brain barrier can be produced in mice. Infusion of 1.8 molal arabinose in water at a rate of 0.64 ml/min for 30 seconds into the internal carotid artery consistently results in ipsilateral brain stai
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 245(2)
Pharmacokinetic parameters of human lymphoblastoid interferon (IFN-alpha) delivery to normal rat brain were examined. IFN-alpha concentrations in brain parenchyma could only be detected 120 min after its intravascular administration, and were 0.003%