Výsledky vyhledávání - "W R, Drobyski"

Akademický článek

DAS181 Treatment of Severe Parainfluenza Virus 3 Pneumonia in Allogeneic Hematopoietic Stem Cell Transplant Recipients Requiring Mechanical Ventilation

Autor: B. Dhakal, A. D’Souza, M. Pasquini, W. Saber, T. S. Fenske, R. B. Moss, W. R. Drobyski, P. Hari, M. Z. Abidi

Publikováno v: Case Reports in Medicine, Vol 2016 (2016)

Parainfluenza virus (PIV) may cause life-threatening pneumonia in allogeneic hematopoietic stem cell transplant (HSCT) recipients. Currently, there are no proven effective therapies. We report the use of inhaled DAS181, a novel sialidase fusion prote

Externí odkaz: https://doaj.org/article/488ac97cd4e94dbaba27c7f54c24623a

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Inhibition of nitric oxide production is associated with enhanced weight loss, decreased survival, and impaired alloengraftment in mice undergoing graft-versus-host disease after bone marrow transplantation

Autor: W R, Drobyski, C A, Keever, G A, Hanson, T, McAuliffe, O W, Griffith

Publikováno v: Blood. 84:2363-2373

The pathophysiologic role of nitric oxide (NO) in graft-versus-host disease (GVHD) was investigated in a murine bone marrow (BM) transplantation model where donor and recipient were H-2-matched but differed at multiple minor histocompatibility antige

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70ea37258885a2463c4647c0385de8d4
https://doi.org/10.1182/blood.v84.7.2363.bloodjournal8472363

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Salvage immunotherapy using donor leukocyte infusions as treatment for relapsed chronic myelogenous leukemia after allogeneic bone marrow transplantation: efficacy and toxicity of a defined T-cell dose

Autor: W R, Drobyski, C A, Keever, M S, Roth, S, Koethe, G, Hanson, P, McFadden, J L, Gottschall, R C, Ash, P, van Tuinen, M M, Horowitz

Publikováno v: Blood. 82:2310-2318

Eight patients who had hematologic relapse of chronic myelogenous leukemia (CML) after undergoing allogeneic bone marrow transplantation (BMT) were treated with leukocyte infusions from the original bone marrow donors. All patients had previously rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b8caabf4515efb32e4b5bef563cf86f
https://doi.org/10.1182/blood.v82.8.2310.bloodjournal8282310

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Detection of residual leukemia by the polymerase chain reaction and sequence-specific oligonucleotide probe hybridization after allogeneic bone marrow transplantation for AKR leukemia: a murine model for minimal residual disease

Autor: W R, Drobyski, L A, Baxter-Lowe, R L, Truitt

Publikováno v: Blood. 81:551-559

Disease relapse after allogeneic bone marrow transplantation (BMT) is a major cause of treatment failure and is thought to evolve from clinically occult residual disease in the recipient. However, the demonstration of minimal residual disease (MRD) i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e4132e046b53f01379341b7d180c74d
https://doi.org/10.1182/blood.v81.2.551.551

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Treatment of relapsed leukemia after unrelated donor marrow transplantation with unrelated donor leukocyte infusions

Autor: D L, Porter, R H, Collins, C, Hardy, N A, Kernan, W R, Drobyski, S, Giralt, M E, Flowers, J, Casper, A, Leahey, P, Parker, R, Mick, B, Bate-Boyle, R, King, J H, Antin

Publikováno v: Blood. 95(4)

The efficacy and toxicity of donor leukocyte infusions (DLI) after unrelated donor bone marrow transplantation (BMT) is largely unknown. We identified 58 recipients of unrelated DLI (UDLI) for the treatment of relapsed disease from the National Marro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::457549ce2220e428a466cd58b661bf8e
https://pubmed.ncbi.nlm.nih.gov/10666193

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T-cell depletion plus salvage immunotherapy with donor leukocyte infusions as a strategy to treat chronic-phase chronic myelogenous leukemia patients undergoing HLA-identical sibling marrow transplantation

Autor: W R, Drobyski, M J, Hessner, J P, Klein, C, Kabler-Babbitt, D H, Vesole, D A, Margolis, C A, Keever-Taylor

Publikováno v: Blood. 94(2)

T-cell depletion (TCD) of the donor marrow graft has been shown to reduce the severity of graft-versus-host disease (GVHD) in patients with chronic-phase (CP) chronic myelogenous leukemia (CML) undergoing HLA-identical sibling allogeneic marrow trans

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a465fa37b0daf3be715c09e751cb43b0
https://pubmed.ncbi.nlm.nih.gov/10397710

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Adoptive immunotherapy for leukemia: donor lymphocytes transduced with the herpes simplex thymidine kinase gene for remission induction. HGTRI 0103

Publikováno v: Human gene therapy. 9(1)

This study will evaluate the safety and efficacy of allogenic donor lymphocyte infusions in patients who have relapsed hematologic malignancies after allogeneic bone marrow transplantation (BMT). Donor lymphocyte transfusions have resulted in the cur

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e41f8a9ede440c051f7fe2c1c20e5116
https://pubmed.ncbi.nlm.nih.gov/9458247

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Donor gamma delta T lymphocytes promote allogeneic engraftment across the major histocompatibility barrier in mice

Autor: W R, Drobyski, D, Majewski

Publikováno v: Blood. 89(3)

T cells that express the alpha beta T-cell receptor are thought to be the T-cell population primarily responsible for facilitating alloengraftment. The role of gamma delta + T cells that comprise only a minority of mature T cells in promoting allogen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::14c64040f4d9a579bbed3e202dfee499
https://pubmed.ncbi.nlm.nih.gov/9028343

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