Zobrazeno 1 - 10
of 4 498
pro vyhledávání: '"W Patrick"'
Autor:
James Thompson, W Patrick Walters, Jianwen A Feng, Nicolas A Pabon, Hongcheng Xu, Brian B Goldman, Demetri Moustakas, Molly Schmidt, Forrest York
Publikováno v:
Artificial Intelligence in the Life Sciences, Vol 3, Iss , Pp 100074- (2023)
Externí odkaz:
https://doaj.org/article/38729ea392e043bb89ec2e372de9b12e
The diffusion learning method, DiffDock, for docking small-molecule ligands into protein binding sites was recently introduced. Results included comparisons to more conventional docking approaches, with DiffDock showing superior performance. Here, we
Externí odkaz:
http://arxiv.org/abs/2412.02889
Autor:
James Thompson, W Patrick Walters, Jianwen A Feng, Nicolas A Pabon, Hongcheng Xu, Brian B Goldman, Demetri Moustakas, Molly Schmidt, Forrest York
Publikováno v:
Artificial Intelligence in the Life Sciences, Vol 2, Iss , Pp 100050- (2022)
While Relative Binding Free Energy (RBFE) calculations have become a mainstay in lead optimization programs, the computational expense of performing these calculations has limited their broader application. Active learning (AL), a machine learning me
Externí odkaz:
https://doaj.org/article/ddb6aa44a7cb41bfb5fdeed6a3246b71
Autor:
Sadeem Munawar Qureshi, Sue Bookey-Bassett, Nancy Purdy, Michael A Greig, Helen Kelly, W Patrick Neumann
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0275890 (2022)
Higher acuity levels in COVID-19 patients and increased infection prevention and control routines have increased the work demands on nurses. To understand and quantify these changes, discrete event simulation (DES) was used to quantify the effects of
Externí odkaz:
https://doaj.org/article/0921c9468ba04857af2b4e535c233b6a
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 9 (2021)
AbstractIn this study, 723 Pinus taedaCronartium quercuum. fusiformefamilywithin-familyP. taeda
Externí odkaz:
https://doaj.org/article/2387abfc7d4d475599121b7f93f7ee5d
Autor:
Jacob Pfeil, Lauren M Sanders, Ioannis Anastopoulos, A Geoffrey Lyle, Alana S Weinstein, Yuanqing Xue, Andrew Blair, Holly C Beale, Alex Lee, Stanley G Leung, Phuong T Dinh, Avanthi Tayi Shah, Marcus R Breese, W Patrick Devine, Isabel Bjork, Sofie R Salama, E Alejandro Sweet-Cordero, David Haussler, Olena Morozova Vaske
Publikováno v:
PLoS Computational Biology, Vol 16, Iss 4, p e1007753 (2020)
Precision oncology has primarily relied on coding mutations as biomarkers of response to therapies. While transcriptome analysis can provide valuable information, incorporation into workflows has been difficult. For example, the relative rather than
Externí odkaz:
https://doaj.org/article/6b18e66d017444afb3146ec81d8a8f6f
Autor:
Hooper, W. Patrick, Javornik, Pavel
We study geodesics on the Necker cube surface, $\mathbf N$, an infinite periodic Euclidean cone surface that is homeomorphic to the plane and is tiled by squares meeting three or six to a vertex. We ask: When does a geodesic on the surface close? Whe
Externí odkaz:
http://arxiv.org/abs/2310.03115
Autor:
Amin Yazdani, W Patrick Neumann, Daniel Imbeau, Philip Bigelow, Mark Pagell, Nancy Theberge, Margo Hilbrecht, Richard Wells
Publikováno v:
Scandinavian Journal of Work, Environment & Health, Vol 41, Iss 2, Pp 111-123 (2015)
OBJECTIVES: Musculoskeletal disorders (MSD) are a major cause of pain, disability, and costs. Prevention of MSD at work is frequently described in terms of implementing an ergonomics program, often a participatory ergonomics (PE) program. Most other
Externí odkaz:
https://doaj.org/article/3147e9b6f2bc4263b0d7ff467134ce9a