Zobrazeno 1 - 10
of 100
pro vyhledávání: '"W P, Weidanz"'
Publikováno v:
The Journal of Immunology. 157:2096-2102
We examined the cellular and molecular basis of the proliferative response of human gamma delta T cells in cultures of PBMC stimulated with blood-stage Plasmodium falciparum malarial Ag. Flow cytometry revealed that maximal gamma delta T cell prolife
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d2b0056d6d0246b0665a515fbd0ca0c
https://doi.org/10.4049/jimmunol.157.5.2096
https://doi.org/10.4049/jimmunol.157.5.2096
Publikováno v:
The Journal of Immunology. 157:1620-1624
We determined the requirement for selected lymphocyte subsets and cytokines in the pathogenesis of experimental murine cerebral malaria (CM) by using gene-targeted knockout and mAb-suppressed mice. Plasmodium berghei ANKA infection induced CM in A 0/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ce159a5d09a76cea168a8df83b0e7f1
https://doi.org/10.4049/jimmunol.157.4.1620
https://doi.org/10.4049/jimmunol.157.4.1620
Publikováno v:
The Journal of Immunology. 154:3985-3990
To determine whether gamma delta T cells are essential for the resolution of acute Plasmodium chabaudi adami (P. c. adami) malaria, we depleted gamma delta T cells from C57BL/6 mice with hamster monoclonal anti-TCR gamma delta Ab treatment. During th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be4526373608507d731b79b818711e6f
https://doi.org/10.4049/jimmunol.154.8.3985
https://doi.org/10.4049/jimmunol.154.8.3985
Publikováno v:
The Journal of Immunology. 153:1187-1194
As assessed by flow cytometry, human gamma delta T cells were shown here to inhibit replication of blood-stage Plasmodium falciparum in vitro in a dose-dependent fashion; no other leukocyte population tested was suppressive. Replication of intraeryth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb32c14deb703a73b39b76467b720f45
https://doi.org/10.4049/jimmunol.153.3.1187
https://doi.org/10.4049/jimmunol.153.3.1187
Publikováno v:
The Journal of Immunology. 152:4557-4562
Because the role of cell-mediated immunity (CMI) in the resolution of blood-stage malaria remains unclear, we examined the question of whether mice completely lacking Ab-mediated immunity (AMI) but possessing some CMI can resolve experimental malaria
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f26251488a7817f4269b90e5634097f
https://doi.org/10.4049/jimmunol.152.9.4557
https://doi.org/10.4049/jimmunol.152.9.4557
Publikováno v:
Parasite immunology. 33(9)
A genetic dissection approach was employed to determine whether the IL-2 receptor complex (IL-2R) comprised of α, β and γ chains is required for the suppression of Plasmodium chabaudi adami parasitemia. Blood-stage infections in IL-2Rγ(c)(-/y) mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f2b8910cdfae3ff40a0db09552a8e57d
https://pubmed.ncbi.nlm.nih.gov/21585397
https://pubmed.ncbi.nlm.nih.gov/21585397
Publikováno v:
The Journal of Immunology. 151:6311-6317
The previously observed expansion of the splenic gamma delta T cell subset was examined during the course of murine malaria to determine whether CD4+ T cells are required. Flow cytometric analysis during the course of Plasmodium chabaudi adami malari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2ce0a2cc0b1af470f06f0a9ea6cc4a1
https://doi.org/10.4049/jimmunol.151.11.6311
https://doi.org/10.4049/jimmunol.151.11.6311
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(12)
gammadelta T cells have a crucial role in cell-mediated immunity (CMI) against P. chabaudi malaria, but delta-chain knockout (KO) (deltao/o) mice and mice depleted of gammadelta T cells with mAb cure this infection. To address the question of why mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6994c3ac1205ee9d4edf1538af866bed
https://pubmed.ncbi.nlm.nih.gov/10358190
https://pubmed.ncbi.nlm.nih.gov/10358190
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 151(6)
We utilized a definitive model of CD8+ T cell deficiency, the beta 2-microglobulin-deficient (beta 2-m0/0) mouse, to determine whether CD8+ T cells are required in the resolution of blood-stage malaria. In a parallel experiment, C57Bl/6 mice treated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7f82f030e1f16a0744c852bdf7840510
https://pubmed.ncbi.nlm.nih.gov/8376774
https://pubmed.ncbi.nlm.nih.gov/8376774
Publikováno v:
Immunology letters. 25(1-3)
The T cell receptor of gamma delta is normally expressed on a small percentage of peripheral lymphocytes. Although the role of gamma delta T cells in the physiologic immune response is still unknown, there is accumulating evidence that gamma delta T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f1b6bee7bc05e01fb0819ba69380606c
https://pubmed.ncbi.nlm.nih.gov/2149360
https://pubmed.ncbi.nlm.nih.gov/2149360