Zobrazeno 1 - 10 of 144 pro vyhledávání: '"W P, Kolb"'
1
Complement and neutrophil activation in the pathogenesis of ischemic myocardial injury
Autor: W. P. Kolb, R. N Pinckard, Robert A. O'Rourke, Frederick L. Grover, Linda M. McManus, C A McMahan, Michael H. Crawford
Publikováno v: Circulation. 78:1449-1458
Complement depletion with cobra venom factor (CVF) before coronary artery ligation has been previously shown to reduce subsequent ischemic myocardial tissue injury in the baboon; however, whether complement depletion after the initiation of acute myo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2788b27c20cc5a7e5f7788bd7e8c9cbf
https://doi.org/10.1161/01.cir.78.6.1449
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2
C1Q receptors on cultured human gingival fibroblasts: analysis of binding properties
Autor: S Bordin, W P Kolb, R C Page
Publikováno v: The Journal of Immunology. 130:1871-1875
The interaction of the purified C1q component of human C with synchronized, quiescent human gingival fibroblasts was investigated, and the presence of a specific binding site was demonstrated. Quantitative binding studies with radioiodinated C1q show
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::0876d8ae3f59b416b2db7591ae8a0d87
https://doi.org/10.4049/jimmunol.130.4.1871
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3
Evidence that C5b recognizes and mediates C8 incorporation into the cytolytic complex of complement
Autor: J L Stewart, W P Kolb, J M Sodetz
Publikováno v: The Journal of Immunology. 139:1960-1964
The aim of this study was to identify constituents of the intermediate C5b-7 complex of human complement that mediate binding of C8 and formation of C5b-8. Analysis of interactions between purified C8 and C5, C6, or C7 indicate that C5 and C8 associa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::139e9f72fe447bb39c48bf1906c5bfec
https://doi.org/10.4049/jimmunol.139.6.1960
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4
C1q binding and C1 activation by various isolated cellular membranes
Autor: S B Storrs, W P Kolb, M S Olson
Publikováno v: The Journal of Immunology. 131:416-422
Cellular and subcellular membranes obtained from heart, liver, and brain tissue from human, baboon, bovine, rabbit, and rat bound highly purified, radioiodinated human C1q with a high affinity (Ka = 10(8) to 10(10) M-1). The majority of these membran
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5c6bb80c00eac2df769a0d96555a5795
https://doi.org/10.4049/jimmunol.131.1.416
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5
The membrane attack mechanism of complement. Isolation and subunit composition of the C5b-9 complex
Autor: W P Kolb, H J Muller-Eberhard
Publikováno v: Journal of Experimental Medicine. 141:724-735
Isolation of the C5b-9 complex from inulin-activated whole human serum was effected by molecular sieve column chromatography employing Biogel A-15 M, preparative Pevikon block electrophoresis, and removal of low density beta-lipoproteins by flotation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1a1e4ded6f327a0ad983b077b361661f
https://doi.org/10.1084/jem.141.4.724
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6
Expression of C5a-like biological activities by the fifth component of human complement (C5) upon limited digestion with noncomplement enzymes without release of polypeptide fragments
Autor: R A Wetsel, W P Kolb
Publikováno v: The Journal of Experimental Medicine
Experimental conditions required for the expression of maximum C5 activation upon limited trypsin hydrolysis were determined to be 0.008 mol of trypsin/mol C5 in a reaction mixture containing 1 mg C5/ml veronal-buffered saline incubated at 37 degrees
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81bad8bfe98c85542277c28b6dc5f212
https://doi.org/10.1084/jem.157.6.2029
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8
Production of Lymphotoxin and Migration Inhibitory Factor by Established Human Lymphocytic Cell Lines
Autor: G. A. Granger, G. E. Moore, J. G. White, P. Matzinger, J. S. Sundsmo, S. Shupe, W. P. Kolb, J. Kramer, P. R. Glade
Publikováno v: The Journal of Immunology. 104:1476-1485
A number of continuous human lymphoid cell lines were examined for in vitro synthesis of the effector molecules, lymphotoxin (LT) and migration-inhibition factor (MIF). Twenty-six of a total of 39 lines established from human peripheral blood lymphoc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::415931dc59944eacd83f057c278a38e2
https://doi.org/10.4049/jimmunol.104.6.1476
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9
Human platelet-initiated formation and uptake of the C5-9 complex of human complement
Autor: T S Zimmerman, W P Kolb
Publikováno v: The Journal of clinical investigation. 57(1)
We have studied the interaction of radiolabeled complement components with normal human platelets, platelets from a patient with paroxysmal nocturnal hemoglobinuria, and rabbit platelets in the absence of known complement activators or in the presenc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::248c569404a3365f7f16310b866ee68a
https://pubmed.ncbi.nlm.nih.gov/812888
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10
Structural similarities between C6 and C7 of human complement
Autor: E R, Podack, W P, Kolb, A F, Esser, H J, Müller-Eberhard
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 123(3)
A new method for the isolation of C6 and C7 by affinity chromatography of human serum with anti-C6 and anti-C7 coupled to Sepharose is described. C6 and C7 prepared by this method are hemolytically fully active, homogeneous proteins obtained in 25% y
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::8cc60b8a2ef042781adc37e0b688bae3
https://pubmed.ncbi.nlm.nih.gov/381516
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