Zobrazeno 1 - 10
of 35
pro vyhledávání: '"W Nikolaus Kühn-Velten"'
Publikováno v:
Case Reports in Nephrology and Dialysis, Vol 13, Iss 1, Pp 70-74 (2023)
The largest study on cyclophosphamide pharmacokinetics in dialysis patients comprises of 6 subjects. In the 2 decades since these data were obtained, dialyser membranes, treatment intensities, and treatment duration have changed considerably making n
Externí odkaz:
https://doaj.org/article/c51a4801992e4faa989747f51a4ed989
Autor:
Peter Huppke, Susann Weissbach, Joseph A. Church, Rhonda Schnur, Martina Krusen, Steffi Dreha-Kulaczewski, W. Nikolaus Kühn-Velten, Annika Wolf, Brenda Huppke, Francisca Millan, Amber Begtrup, Fatima Almusafri, Holger Thiele, Janine Altmüller, Peter Nürnberg, Michael Müller, Jutta Gärtner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
The NRF2 transcription factor regulates the response to stress in mammalian cells. Here, the authors show that activating mutations in NRF2, commonly found in cancer cells, are found in four patients with a multisystem disorder characterized by immun
Externí odkaz:
https://doaj.org/article/afa5f18f07b548228b00ab048e187a66
Autor:
Eleni Chatzidimitriou, Dominika Średnicka-Tober, Juan Wang, Carlo Leifert, Hannah Davis, Gultakin Hasanaliyeva, Per Ole Iversen, Catherine Hadall, Hans-Wolfgang Hoppe, W Nikolaus Kühn-Velten, Chris J. Seal, Steven Rushton, Vanessa Vigar, Nikolaos Volakakis, Marcin Barański, Anthony W. Watson, Leonidas Rempelos, Amelia Magistrali
Publikováno v:
The American Journal of Clinical Nutrition. 115:364-377
BACKGROUND Observational studies have linked pesticide exposure to various diseases, whereas organic food consumption has been associated with positive health outcomes. Organic farming standards prohibit the use of most pesticides, and organic food c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c27c555a7e344e8321ece4889bbed2f
https://doi.org/10.1093/ajcn/nqab308
https://doi.org/10.1093/ajcn/nqab308
Autor:
Julius J. Schmidt, Viktor Arelin, Jan T. Kielstein, Gabriele Eden, Nathalie Kayser, Hendrik Suhling, W. Nikolaus Kühn-Velten
Publikováno v:
Clinical Nephrology. 85:353-357
The synthetic opioid methadone hydrochloride has a low molecular weight of 346 D, a high volume of distribution (4 - 7 L/kg), and is lipophilic. It is used as an analgesic and for the maintenance treatment of opiate dependence. In drug addicts, metha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc9775ceff2f2aff4c77b9198bd62995
https://doi.org/10.5414/cn108724
https://doi.org/10.5414/cn108724
Publikováno v:
BMJ case reports. 2018
High cut-off (HCO) haemodialysis removes free light chains in patients with multiple myeloma. This is possible as HCO dialysers allow clearance of molecules up to a molecular weight of 65 kDa. In contrast, high-flux dialysers, which are used in routi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::518c1670d2e7e65bacb8c2a1ffebccdd
https://pubmed.ncbi.nlm.nih.gov/29301798
https://pubmed.ncbi.nlm.nih.gov/29301798
Autor:
Anna Bertram, Julius J. Schmidt, Hendrik Suhling, Jan T. Kielstein, W. Nikolaus Kühn-Velten, Andrea Schneider, Olaf Wiesner
Publikováno v:
Clinical Kidney Journal
Antidepressants, especially amitriptyline, are among the most frequent drug classes involved in intoxications. Despite its small molecular weight, amitriptyline is not considered to be eliminated by extracorporeal treatment methods due to its high pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8140aa9c29c70cd3b2b599b6618b62ff
http://europepmc.org/articles/PMC4655799
http://europepmc.org/articles/PMC4655799
Autor:
W. Nikolaus Kühn-Velten, Julius J. Schmidt, Jan T. Kielstein, Ann-Kathrin Strunk, Eva Baroke, Olaf Wiesner
Publikováno v:
Clinical Nephrology. 84:104-107
Hemodialysis is the extracorporeal treatment of choice for various life-threatening intoxications, with the exception of highly protein-bound substances, which are preferably removed by charcoal hemoperfusion. This technique, however, is limited by i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2491dca045c3b9f0dc9deb3f20231523
https://doi.org/10.5414/cn108441
https://doi.org/10.5414/cn108441
Publikováno v:
Journal of Cutaneous Pathology. 40:935-944
Background Nephrogenic systemic fibrosis (NSF) represents a rare fibrosing disorder occurring after administration of gadolinium-containing contrast agents during renal insufficiency. In order to prove the effect of gadolinium elimination on clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e754fa5ef59ae3394f40069fc10e093
https://doi.org/10.1111/cup.12214
https://doi.org/10.1111/cup.12214
Publikováno v:
labm. 37:167-180
Detection and quantification of synthetic cannabinoids (synonym: cannabimimetics) used as a substitute for natural cannabis has been a real toxicological and forensic issue since 2008. On the basis of a short overview of the pharmacological principle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::193815db261b70d78f4d7789fdfa4514
https://doi.org/10.1515/labmed-2012-0059
https://doi.org/10.1515/labmed-2012-0059
Autor:
Peter Huppke, Susann Weissbach, Joseph A. Church, Rhonda Schnur, Martina Krusen, Steffi Dreha-Kulaczewski, W. Nikolaus Kühn-Velten, Annika Wolf, Brenda Huppke, Francisca Millan, Amber Begtrup, Fatima Almusafri, Holger Thiele, Janine Altmüller, Peter Nürnberg, Michael Müller, Jutta Gärtner
Publikováno v:
Nature Communications
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Transcription factor NRF2, encoded by NFE2L2, is the master regulator of defense against stress in mammalian cells. Somatic mutations of NFE2L2 leading to NRF2 accumulation promote cell survival and drug resistance in cancer cells. Here we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2b76513a6479b1e772c60f340e7c48b5
https://pubmed.ncbi.nlm.nih.gov/29018201
https://pubmed.ncbi.nlm.nih.gov/29018201