Zobrazeno 1 - 10
of 137
pro vyhledávání: '"W Nicholas Haining"'
Autor:
Lan Chen, Beatriz Millare, Jeremy Chen, Aaron Cooper, Natalie Bezman, Angela Boroughs, Suchismita Mohanty, David DeTomaso, Amy-Jo Casbon, Thomas J Gardner, Anzhi Yao, Ashley Cass, Alma Gomez, Manching Ku, Lionel Berthoin, Meng Lim, Azalea Ong, Vince Thomas, Nicholas Quant, Brian Hsu, Levi Gray-Rupp, W Nicholas Haining
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/5e4a90e7ee90474c9a89859560f13aa5
Autor:
Yashaswi Shrestha, Michael Quigley, Travis Hughes, Robert T Manguso, Natalie B Collins, Rose Al Abosy, Brian C Miller, Kevin Bi, Qihong Zhao, Jeffrey J Ishizuka, Kathleen B Yates, Hans W Pope, Marc Wadsworth, Alex K Shalek, Jesse S Boehm, William C Hahn, John G Doench, W Nicholas Haining
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 3 (2022)
Background Oncogenes act in a cell-intrinsic way to promote tumorigenesis. Whether oncogenes also have a cell-extrinsic effect on suppressing the immune response to cancer is less well understood.Methods We use an in vivo expression screen of known c
Externí odkaz:
https://doaj.org/article/2f18639e65804873a00ab93aef07c6bc
Autor:
Prakash K Gupta, Jernej Godec, David Wolski, Emily Adland, Kathleen Yates, Kristen E Pauken, Cormac Cosgrove, Carola Ledderose, Wolfgang G Junger, Simon C Robson, E John Wherry, Galit Alter, Philip J R Goulder, Paul Klenerman, Arlene H Sharpe, Georg M Lauer, W Nicholas Haining
Publikováno v:
PLoS Pathogens, Vol 11, Iss 10, p e1005177 (2015)
Exhausted T cells express multiple co-inhibitory molecules that impair their function and limit immunity to chronic viral infection. Defining novel markers of exhaustion is important both for identifying and potentially reversing T cell exhaustion. H
Externí odkaz:
https://doaj.org/article/a33577d938d04eef98014e4ae8a823b4
Autor:
Manish J Butte, Sun Jung Lee, Jonathan Jesneck, Mary E Keir, W Nicholas Haining, Arlene H Sharpe
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e40032 (2012)
CD28 is the major costimulatory receptor required for activation of naïve T cells, yet CD28 costimulation affects the expression level of surprisingly few genes over those altered by TCR stimulation alone. Alternate splicing of genes adds diversity
Externí odkaz:
https://doaj.org/article/bbd92caaa7704dbf954f3ca038b4c4ee
Supplementary Data from CDK4/6 Inhibition Augments Antitumor Immunity by Enhancing T-cell Activation
Autor:
Kwok-Kin Wong, Nathanael S. Gray, David A. Barbie, Geoffrey I. Shapiro, Haribabu Arthanari, Norman E. Sharpless, W. Nicholas Haining, Jerome Ritz, Gordon J. Freeman, Sangeetha Palakurthi, Raphael Bueno, Genevieve M. Boland, Viswanath Gunda, Sareh Parangi, Jochen H. Lorch, William G. Richards, Jay C. Strum, Patrick J. Roberts, Eric Haines, Amanda J. Rode, Megan E. Cavanaugh, Ting Chen, Peng Gao, Hua Zhang, Yanxi Zhang, Annan Yang, Lauren E. Bufe, Max M. Quinn, Ashley A. Merlino, Patrick H. Lizotte, John E. Bisi, Jessica A. Sorrentino, Grit S. Herter-Sprie, Chensheng W. Zhou, Michaela Bowden, Cloud P. Paweletz, Elena Ivanova, Amir R. Aref, Hongye Liu, Wei Huang, Sandeep Chhabra, Kathleen Yates, Ruben Dries, Shuai Li, Russell W. Jenkins, Eric S. Wang, Jiehui Deng
Figure S1. Characterization of cells and CDK4/6 inhibitors; Figure S2. CDK6 phosphorylates serine residues of the regulatory domain of NFAT4 (NFATc3); Figure S3. Analysis of lung tumor immune infiltrates after CDK4/6 inhibition from KrasG12D (Kras),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22a01c7e72b06ed917fff29065c873f6
https://doi.org/10.1158/2159-8290.22531849.v1
https://doi.org/10.1158/2159-8290.22531849.v1
Autor:
Lee M. Nadler, Robert L. Coffman, George Demetri, Patrick Wen, Jeffrey Morgan, Jeffrey Kutok, Xiaochun Li, Donna Neuberg, Paul Sims, Suzanne George, Kate Russell, Steven Rivoli, Jill Angelosanto, John Evans, Thomas Brenn, Linda Drury, Holger Kanzler, Jeffrey Davies, W. Nicholas Haining
Supplementary Data from CpG Oligodeoxynucleotides Alter Lymphocyte and Dendritic Cell Trafficking in Humans
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f9a9e677a7e9db4aaa9e8a531e30862
https://doi.org/10.1158/1078-0432.22439638.v1
https://doi.org/10.1158/1078-0432.22439638.v1
Autor:
Lee M. Nadler, Robert L. Coffman, George Demetri, Patrick Wen, Jeffrey Morgan, Jeffrey Kutok, Xiaochun Li, Donna Neuberg, Paul Sims, Suzanne George, Kate Russell, Steven Rivoli, Jill Angelosanto, John Evans, Thomas Brenn, Linda Drury, Holger Kanzler, Jeffrey Davies, W. Nicholas Haining
Purpose: CpG oligodeoxynucleotides (CpG-ODN) are being investigated as cancer vaccine adjuvants because they mature plasmacytoid dendritic cells (PDC) into potent antigen-presenting cells. CpG-ODN also induce PDC to secrete chemokines that alter lymp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d711fbde563e84f3fee23c9e76d03378
https://doi.org/10.1158/1078-0432.c.6517075.v1
https://doi.org/10.1158/1078-0432.c.6517075.v1
Autor:
Angelo A. Cardoso, Lee M. Nadler, Stephen E. Sallan, Rob Pieters, Monique L. den Boer, Paolo Ghia, Nilufer P. Seth, Scott A. Armstrong, Zhinan Xia, Sascha Ansén, W. Nicholas Haining, Sara Maia
Supplementary Tables 1-3 from Gene Expression Profiling Identifies BAX-δ as a Novel Tumor Antigen in Acute Lymphoblastic Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8452e573875443b6077216385665ec9
https://doi.org/10.1158/0008-5472.22367648
https://doi.org/10.1158/0008-5472.22367648
Autor:
Brendan Galvin, Grace Zheng, Robby Moot, Michelle Nguyen, Michelle Tan, Rene Sit, Lionel Berthoin, David DeTomaso, Sofia Kyriazopoulou Panagiotopoulou, Shan Sabri, Jun Feng, Manching Ku, Anzhi Yao, Andrea Liu, Jennifer McDevitt, Matt Drever, Stephen Santoro, Aaron Cooper, Susie Jun, W Nicholas Haining, Tarjei Mikkelsen
Publikováno v:
Regular and Young Investigator Award Abstracts.
Publikováno v:
Cancer Discovery, 12(10), 2244-2248. AMER ASSOC CANCER RESEARCH
Summary: Tumor-specific cytotoxic T cells unleashed by the blockade of immune checkpoints have to overcome a hostile tumor microenvironment (TME). They start from very small numbers of T cells with tumor antigen specificity and, despite expansion, li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1996ce806bb9ca8f6d579332d66d9c5b
http://hdl.handle.net/1887/3566487
http://hdl.handle.net/1887/3566487