Zobrazeno 1 - 10
of 82
pro vyhledávání: '"W N Valentine"'
Publikováno v:
The Journal of clinical investigation. 26(6)
Autor:
J S, Lawrence, W N, Valentine
Publikováno v:
Blood. 2(1)
Autor:
W N, Valentine, D E, Paglia
Publikováno v:
Advances in experimental medicine and biology. 307
Autor:
W N, Valentine, D E, Paglia
Publikováno v:
The Journal of laboratory and clinical medicine. 115(1)
Autor:
D E Paglia, W N Valentine
Publikováno v:
Journal of Biological Chemistry. 250:7973-7979
A 5'-nucleotidase with unique specificity has been identified in the soluble fraction of normal human erythrocytes. It mediates the hydrolytic dephosphorylation of pyrimidine 5'-ribosemonophosphates but is catalytically ineffective with purine nucleo
Autor:
W. N. Valentine
Publikováno v:
Archives of Internal Medicine. 135:1307-1313
Publikováno v:
British Journal of Haematology. 34:61-68
SUMMARY The heterogeneity of pyruvate kinase (PK) deficiency associated with hereditary haemolytic anaemia is emphasized by studies of a kindred harbouring two distinct mutant forms of this enzyme, both of which were kinetically defective with marked
Publikováno v:
Blood. 72:1054-1059
The proband with lifelong hemolytic anemia has a high K0.5s phosphoenolypyruvate (PEP) erythrocyte pyruvate kinase (PK) variant substantially but incompletely normalized by the allosteric modifier fructose-1,6-diphosphate (F-1,6-P2) with conversion o
Publikováno v:
British Journal of Haematology. 35:331-340
Autor:
W N Valentine
Publikováno v:
Annual Review of Medicine. 23:93-100
The human red cell, biologically speaking, is intriguingly but deceptively simplistic. Freely floating, separable from contaminating cell types, devoid of a nucleus and cellular organelles, restricted in its energy needs and in the mechanisms for mee