Výsledky vyhledávání - "W N, Johnston"

Suppression of experimental arthritis by gene transfer of interleukin 1 receptor antagonist cDNA

Autor: J. S. Haskill, R R Brown, Sergei S. Makarov, John H. Schwab, S K Anderle, Albert S. Baldwin, John C. Olsen, W N Johnston

Restoration of the impaired balance between pro- and antiinflammatory cytokines should provide effective treatment of rheumatoid arthritis. Gene therapy has been proposed as an approach for delivery of therapeutic proteins to arthritic joints. Here,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6937b4914352cc4d21a021e50e8de46e
https://europepmc.org/articles/PMC40246/

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Retrovirus mediated in vivo gene transfer to synovium in bacterial cell wall-induced arthritis in rats

Autor: S S, Makarov, J C, Olsen, W N, Johnston, J H, Schwab, S K, Anderle, R R, Brown, J S, Haskill

Publikováno v: Gene therapy. 2(6)

Gene therapy may provide an effective alternative to conventional approaches for treating rheumatoid arthritis. Direct in vivo gene delivery to synovium has a distinct advantage with respect to clinical use. To date, retroviral vectors are the best s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::69e1fdc0d5fa906cc3d05f04142cbdf5
https://pubmed.ncbi.nlm.nih.gov/7584118

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