Zobrazeno 1 - 10
of 52
pro vyhledávání: '"W Melkus"'
Autor:
Flávia Sardela de Miranda, Maribel Castro, Nicole Remmert, Sharda P. Singh, Rakhshanda Layeequr Rahman, Michael W. Melkus
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Breast cancer is the second most common cancer among women in the United States in which the standard of care treatment is surgery with adjunctive therapy. Cryoablation, which destroys the tumor using extremely cold temperatures while preserving the
Externí odkaz:
https://doaj.org/article/44b3881dc0e34fc39d59a4d5b83cb042
Autor:
Fahmida Rasha, Geetha Priya Boligala, Mingxiao V. Yang, Dalia Martinez-Marin, Isabel Castro-Piedras, Kathryn Furr, Annie Snitman, Sonia Y. Khan, Luis Brandi, Maribel Castro, Hafiz Khan, Nusrat Jahan, Sharilyn Almodovar, Michael W. Melkus, Kevin Pruitt, Rakhshanda Layeequr Rahman
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-18 (2023)
Abstract Background Dishevelled paralogs (DVL1, 2, 3) are key mediators of Wnt pathway playing a role in constitutive oncogenic signaling influencing the tumor microenvironment. While previous studies showed correlation of β-catenin with T cell gene
Externí odkaz:
https://doaj.org/article/8ea1b3462046437d99d48335c2b3d3bc
Autor:
Michael W. Melkus, Loc Le, Arif J. Siddiqui, Adebayo J. Molehin, Weidong Zhang, Samra Lazarus, Afzal A. Siddiqui
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
For decades, mass drug treatment with praziquantel (PZQ) has been utilized to treat schistosomiasis, yet reinfection and the risk of drug resistance are among the various factors precluding successful elimination of schistosomiasis. Tractable models
Externí odkaz:
https://doaj.org/article/261fc6ad3ef94760b73799ea6a470581
Autor:
Cheng Jiang, Junxuan Lu, Hongbo Hu, Min Ye, Sangyub Kim, Wei Wu, Kartick Pramanik, Peixin Jiang, Su-Ni Tang, Shutao Yin, Michael W. Melkus, Yinhui Dong, Yong Zhang
Bufalin is a major cardiotonic compound in the traditional Chinese medicine, Chansu, prepared from toad skin secretions. Cell culture studies have suggested an anticancer potential involving multiple cellular processes, including differentiation, apo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac7e90f24d82a32e0daa1517395425d1
https://doi.org/10.1158/1535-7163.c.6537846.v1
https://doi.org/10.1158/1535-7163.c.6537846.v1
Autor:
Cheng Jiang, Junxuan Lu, Hongbo Hu, Min Ye, Sangyub Kim, Wei Wu, Kartick Pramanik, Peixin Jiang, Su-Ni Tang, Shutao Yin, Michael W. Melkus, Yinhui Dong, Yong Zhang
Table S3 shows effect of bufalin on cyclins (CCN) and mini-chromosome maintenance (MCM) genes in LNCaP cells exposed for 24 h. Expressed relative to control set as unity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b577c4a9f7ffc36292205d8758d5102
https://doi.org/10.1158/1535-7163.22504770
https://doi.org/10.1158/1535-7163.22504770
Autor:
Cheng Jiang, Junxuan Lu, Hongbo Hu, Min Ye, Sangyub Kim, Wei Wu, Kartick Pramanik, Peixin Jiang, Su-Ni Tang, Shutao Yin, Michael W. Melkus, Yinhui Dong, Yong Zhang
Figure S1 shows A. Concentration-dependent reduction of number of adherent LNCaP cells exposed to increasing concentrations of bufalin for 96 h; B. Representative photomicrograph of LNCaP cells exposed to bufalin at 2 concentrations for 48 h. Figure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4eee35c0fa17d5f3ad7d297a6931708f
https://doi.org/10.1158/1535-7163.22504779
https://doi.org/10.1158/1535-7163.22504779
Autor:
Fahmida Rasha, Mingxiao V Yang, Isabel Castro-Piedras, Kathryn L. Furr, Annie Snitman, Sonia Y. Khan, Luis Brandi, Hafiz Khan, Nusrat Jahan, Michael W. Melkus, Kevin Pruitt, Rakhshanda Layeequr Rahman
Publikováno v:
Cancer Research. 82:P5-10
Aberrant Wnt signaling contributes to every stage of tumorigenesis from immunosuppression in the tumor microenvironment (TME) and reduced tumor infiltrating lymphocytes (TIL) activity in the tumor niche to modulating several cancer hallmarks such as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1b7fb1f45724d2250f6f294ab6d54169
https://doi.org/10.1158/1538-7445.sabcs21-p5-10-04
https://doi.org/10.1158/1538-7445.sabcs21-p5-10-04
Autor:
Juan U Rojo, Michael W Melkus, Kameswara Rao Kottapalli, Oscar E Okiya, Justin Sudduth, Weidong Zhang, Adebayo J Molehin, Darrick Carter, Afzal A Siddiqui
Publikováno v:
PLoS ONE, Vol 12, Iss 2, p e0171677 (2017)
Schistosomiasis is a neglected parasitic disease of major public health concern as it affects over 250 million people in developing countries. Currently there is no licensed vaccine available against schistosomiasis. The Schistosoma mansoni calpain p
Externí odkaz:
https://doaj.org/article/43276af558654fccb8e7e0a38ed3f176
Publikováno v:
Annals of surgical oncology. 30(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::1ab1bbb5428aad2ed512c2e1aca10a2a
https://pubmed.ncbi.nlm.nih.gov/36171531
https://pubmed.ncbi.nlm.nih.gov/36171531
Autor:
Sonia Y, Khan, Annie, Snitman, Zaina, Habrawi, Sybil, Crawford, Michael W, Melkus, Rakhshanda, Layeequr Rahman
Publikováno v:
Annals of Surgical Oncology. 30:1040-1041
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aaf22742383032c8f875bf81cf11a294
https://doi.org/10.1245/s10434-022-12610-0
https://doi.org/10.1245/s10434-022-12610-0