Zobrazeno 1 - 10
of 3 061
pro vyhledávání: '"W Macdonald"'
Autor:
Sina A. Gharib, Rachna Vemireddy, Joseph J. Castillo, Brendy S. Fountaine, Theo K. Bammler, James W. MacDonald, Rebecca L. Hull-Meichle, Sakeneh Zraika
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Insulin secretion is impaired in individuals with cystic fibrosis (CF), contributing to high rates of CF-related diabetes (CFRD) and substantially increasing disease burden. To develop improved therapies for CFRD, better knowledge of pancrea
Externí odkaz:
https://doaj.org/article/02eecb3558cb4daeb1a5360a32a28b02
Autor:
Olga Nanova, David M. Cooper, Andrew C. Kitchener, Graham I. H. Kerley, Thomas P. Gnoske, Julian C. Kerbis Peterhans, Velizar Simeonovski, Bruce D. Patterson, David W. Macdonald, Nobuyuki Yamaguchi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract The lion (Panthera leo) was extirpated from the Cape region of South Africa during the mid-nineteenth century. Whilst historically classified as a distinct subspecies known as the Cape lion (P. l. melanochaita), recent molecular studies chal
Externí odkaz:
https://doaj.org/article/e9d4becc80954a749dbaf9f2ca152afa
Autor:
Brennan H. Baker, Sheela Sathyanarayana, Adam A. Szpiro, James W. MacDonald, Alison G. Paquette
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-25 (2024)
Abstract Missing covariate data is a common problem that has not been addressed in observational studies of gene expression. Here, we present a multiple imputation method that accommodates high dimensional gene expression data by incorporating princi
Externí odkaz:
https://doaj.org/article/cfe23f7d729542beb02b0d1b2ce36059
Publikováno v:
npj Biodiversity, Vol 3, Iss 1, Pp 1-12 (2024)
Abstract Protected areas are an important tool for wildlife conservation; however, research is increasingly revealing both biases and inadequacies in the global protected area network. One common criticism is that protected areas are frequently locat
Externí odkaz:
https://doaj.org/article/9dd50b8d4a074ac480d7df9b7db67277
Autor:
A. Hinsley, D. W. S. Challender, S. Masters, D. W. Macdonald, E. J. Milner-Gulland, J. Fraser, J. Wright
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Unsustainable wildlife trade imperils thousands of species, but efforts to identify and reduce these threats are hampered by rapidly evolving commercial markets. Businesses trading wildlife-derived products innovate to remain competitive, an
Externí odkaz:
https://doaj.org/article/bb491a485a53412aa769624342520187
Autor:
Kevin A. Lidberg, Kendan Jones-Isaac, Jade Yang, Jacelyn Bain, Lu Wang, James W. MacDonald, Theo K. Bammler, Justina Calamia, Kenneth E. Thummel, Catherine K. Yeung, Stefanie Countryman, Paul Koenig, Jonathan Himmelfarb, Edward J. Kelly
Publikováno v:
npj Microgravity, Vol 10, Iss 1, Pp 1-14 (2024)
Abstract The microgravity environment aboard the International Space Station (ISS) provides a unique stressor that can help understand underlying cellular and molecular drivers of pathological changes observed in astronauts with the ultimate goals of
Externí odkaz:
https://doaj.org/article/080dc77d0559426aa337057d6101081e
Autor:
Samuel A. Cushman, Zaneta M. Kaszta, Patrick Burns, Christopher R. Hakkenberg, Patrick Jantz, David W. Macdonald, Jedediah F. Brodie, Mairin C.M. Deith, Scott Goetz
Publikováno v:
Ecological Informatics, Vol 83, Iss , Pp 102832- (2024)
Species distribution modeling (SDM) is a fundamental tool in theoretical and applied ecology. However, relatively little is known about the performance of different approaches for scale optimization, model selection, and algorithmic prediction in the
Externí odkaz:
https://doaj.org/article/7093467999ae46dc91786eb88bf3baa3
Autor:
Elisa Panjang, Hong Ye Lim, Robert J. Thomas, Benoit Goossens, Andrew J. Hearn, David W. Macdonald, Joanna Ross, Seth Timothy Wong, Roshan Guharajan, Azlan Mohamed, Penny C. Gardner, Sharon Koh, Cheryl Cheah, Marc Ancrenaz, Isabelle Lackman, Robert Ong, Reuben Nilus, Alex Hastie, Jedediah F. Brodie, Alys Granados, Olga Helmy, Olivia Magritta Lapis, Donna Simon, Glyn Davies, Siew Te Wong, Mark Rampangajouw, Hisashi Matsubayashi, Chihiro Sano, Rebecca K. Runting, Symphorosa Sipangkui, Nicola K. Abram
Publikováno v:
Global Ecology and Conservation, Vol 52, Iss , Pp e02962- (2024)
Pangolins are the most trafficked mammals in the world and are severely threatened by poaching the loss, degradation, and fragmentation of habitat. In Malaysian Borneo, conservation initiatives for the Sunda pangolin (Manis javanica) are hindered by
Externí odkaz:
https://doaj.org/article/f26f768bd5e84ac4986385da964bc2f1
Autor:
Julius G. Bright Ross, Andrew Markham, Christina D. Buesching, Catherine Hambly, John R. Speakman, David W. Macdonald, Chris Newman
Publikováno v:
Movement Ecology, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract Background Optimal management of voluntary energy expenditure is crucial to the survival and reproductive success of wild animals. Nevertheless, a growing appreciation of inter-individual variation in the internal state driving movement sugg
Externí odkaz:
https://doaj.org/article/9393cbd27f594c2e8db79fcdf5769f61
Publikováno v:
Glomerular Diseases, Vol 4, Iss 1, Pp 49-63 (2024)
Background: The first spatially resolved transcriptomics platforms, GeoMx (Nanostring) and Visium (10x Genomics) were launched in 2019 and were recognized as the method of the year by Nature Methods in 2020. The subsequent refinement and expansion of
Externí odkaz:
https://doaj.org/article/74aa88bd3b7b4200ac6804f26a76fdbf