Zobrazeno 1 - 10
of 125
pro vyhledávání: '"W M Thurlbeck"'
Autor:
Thomas V. Colby, Reuben M. Cherniack, Andrew Flint, W. M. Thurlbeck, Kevin K. Brown, Talmadge E. King, James A. Waldron, Marvin I. Schwarz, Janet A. Tooze
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 164:1025-1032
It is hypothesized that the extent and severity of fibrosis and cellularity found on lung biopsy determine the prognosis and response to therapy in idiopathic pulmonary fibrosis (IPF). The objective of this study was to determine which histopathologi
Autor:
Talmadge E. King, Marvin I. Schwarz, Lynn M. Ackerson, James A. Waldron, Thomas V. Colby, Andrew Flint, W. M. Thurlbeck, Reuben M. Cherniack
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 151:1180-1188
The early stage of idiopathic pulmonary fibrosis (IPF) is thought to involve a smaller number of alveoli and to be characterized predominantly by cellularity and minimal fibrosis, whereas advanced disease involves a large number of alveoli and is cha
Autor:
Talmadge E. King, W. M. Thurlbeck, James A. Waldron, Hyde Dm, McDermott T, Thomas V. Colby, Flint Wm, Lynn M. Ackerson, Reuben M. Cherniack
Publikováno v:
American Review of Respiratory Disease. 146:1042-1047
The objective of this study was to determine the accuracy of a semiquantitative method of assessing the relative degree of cellularity and fibrosis compared with a morphometric analysis of specific histopathologic features in idiopathic pulmonary fib
Publikováno v:
Scandinavian Journal of Clinical and Laboratory Investigation. 52:707-715
Left pneumonectomy was performed on 4 week-old male Fischer-344 rats. Changes in DNA biosynthesis and the activities of related enzymes were studied in the contralateral lungs of the pneumonectomized animals (n = 55) and compared with sham-operated (
Publikováno v:
Investigative Radiology. 25:392-401
Autor:
W. M. Thurlbeck
Publikováno v:
Chest. 97:6S-10
Publikováno v:
Pediatric pulmonology. 24(1)
We compared the ontogeny of collagen (hydroxyproline), elastin (desmosine), soluble protein, and DNA in the lungs of rate and humans during gestation and postnatal life. In humans, lung weight/body weight ratios declined faster during gestation than
Publikováno v:
Pediatric pulmonology. 23(2)
Triamcinolone acetonide (TAC) has a potent teratogenic effect on various mammalian fetal tissues as well as a steroid effect on the lung. Less well documented is the fact that it produces profound oligohydramnios. We wished to determine what effect T
Publikováno v:
Pediatric pulmonology. 22(4)
We correlated clinical, biochemical, and morphologic findings in the lungs of 48 infants dying of either bronchopulmonary dysplasia (BPD) or hyaline membrane disease (HMD) to obtain a better idea of the disease process. The infants ranged from 24 wee