Zobrazeno 1 - 10
of 98
pro vyhledávání: '"W M Kast"'
Autor:
Elena Wüstenhagen, W. M. Kast, Inka Negwer, Gilles A. Spoden, Fatima Boukhallouk, Marc A. Schneider, Kaloian Koynov, Luise Florin, L. Hampe
Publikováno v:
Journal of virology. 90(23)
The human papillomavirus (HPV) capsid protein L2 is essential for viral entry. To gain a deeper understanding of the role of L2, we searched for novel cellular L2-interacting proteins. A yeast two-hybrid analysis uncovered the actin-depolymerizing fa
Autor:
Thomas Bauknecht, R. M. P. Brandt, J.H. de Jong, W. M. Kast, R Offringa, G J Fleuren, Maaike E. Ressing, Cornelis J. M. Melief, W.J. van Driel, Gemma G. Kenter, Howard M. Grey, P Hoogerhout, A Sette, Esteban Celis, B J Trimbos
Publikováno v:
Journal of immunotherapy (Hagerstown, Md., 23(2), 255-266. Lippincott Williams and Wilkins
Human papillomavirus type 16 (HPV16)-encoded E7 oncoprotein is constitutively expressed in cervical carcinoma cells and is required for cellular transformation to be maintained. The E7 protein, therefore, forms an attractive target for T-cell-mediate
Autor:
Robert W. Tindle, Tracy Doan, Karen A. Herd, Gordon Dougan, W. M. Kast, Michael D. Street, Patricia Londoño
Publikováno v:
Archives of Virology. 144:1323-1343
Work from a number of laboratories including our own has shown that foreign B-epitopes inserted into the c/e1-region of Hepatitis B core antigen (HBcAg) elicit powerful antibody responses when mice are immunised with the recombinant core particles. I
Autor:
Sanne Weijzen, Macedo Mf, Michele Carbone, de Visser Ke, Markwin P. Velders, Michael P. Rudolf, Loviscek K, W. M. Kast, John Nieland
Publikováno v:
Critical Reviews™ in Immunology. 18:7-27
As the nature of the T cell immune response is defined by T cell receptor recognition of small protein fragments, referred to as peptides, the identification of peptides would lead us to understanding and directing the T-cell-mediated immune response
Publikováno v:
The Journal of Immunology. 159:5545-5549
Bispecific Abs (BsAb) represent a novel format of immunotherapy, recognizing immune effector cells (e.g., T cells), on the one hand, and target cells (e.g., tumor cells), on the other hand. To be successful, cross-linking of the two cell types is nec
Publikováno v:
Current Opinion in Immunology. 8:651-657
The application of molecularly defined vaccines composed of a limited number of tumor-specific T cell epitopes has resulted in protective antitumor T cell immunity in several mouse tumor models. The first encouraging results with such vaccines have b
Publikováno v:
The Journal of Immunology. 156:3911-3918
CTL can play an important role in the defense against tumors. Protective CTL-mediated immunity can be established in animal tumor models after vaccination with synthetic peptides representing CTL epitopes. We now report that immunization with synthet
Publikováno v:
The Journal of Immunology. 156:3308-3314
The impact of the MHC class I peptide binding stability on the immunogenicity of particular peptide Ags in class I-restricted cytotoxic T lymphocyte responses is not clearly established. Therefore, we have determined the dissociation rate of each pep
Autor:
C. J. M. Melief, René E. M. Toes, M. Hartman, Mariet C.W. Feltkamp, R. J. J. Blom, M. E. Ressing, R.M.P. Brandt, M. P. M. Vierboom, W. M. Kast, Rienk Offringa
Publikováno v:
Scopus-Elsevier
Introduction The T-cell arm of the immune system plays an important role in the defence against viruses and virus-induced tumours [ 1,2]. Virus-induced tumours can be eradicated by both CD8' cytotoxic T-lymphocytes (CTLs) and CD4+ T-helper lymphocyte