Zobrazeno 1 - 10
of 16
pro vyhledávání: '"W M Flanagan"'
Autor:
Andrea Milic, Nandita Bhattacharya, Jeffrey C H Donovan, Joyce M. Slingerland, W. M. Flanagan, Sandrine Cariou
Publikováno v:
Proceedings of the National Academy of Sciences. 97:9042-9046
Estrogens and antiestrogens influence the G 1 phase of the cell cycle. In MCF-7 breast cancer cells, estrogen stimulated cell cycle progression through loss of the kinase inhibitor proteins (KIPs) p27 and p21 and through G 1 cyclin-dependent kinase (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90671c416d562919836bbd6e03429862
https://doi.org/10.1073/pnas.160016897
https://doi.org/10.1073/pnas.160016897
Publikováno v:
The Journal of Immunology. 159:812-819
IL-4 is a pleiotrophic cytokine that has been shown to affect cells of the central nervous system. We have demonstrated that IL-4 inhibits DNA synthesis and proliferation in human astroglia expressing IL-4 receptors. In this study, we sought to ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d80c4391cffa998deccac322b7ffbd05
https://doi.org/10.4049/jimmunol.159.2.812
https://doi.org/10.4049/jimmunol.159.2.812
Autor:
W M Flanagan, Gerald R. Crabtree
Publikováno v:
Journal of Biological Chemistry. 267:399-406
T-cell activation is a complex process mediated by cell membrane molecules including the T-cell antigen receptor (TCR), adhesive molecules, and cytokine receptors that collectively produce an increase in intracellular Ca2+, and activation of protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0b166cb42d7f4d2ebc7eaca11c3d292
https://doi.org/10.1016/s0021-9258(18)48508-0
https://doi.org/10.1016/s0021-9258(18)48508-0
Publikováno v:
Journal of Virology. 65:769-786
The cistrons encoding the herpes simplex virus type 1 (HSV-1) UL37 and UL38 genes are adjacent to one another but are transcribed from opposite strands of the viral DNA. The UL37 gene encodes a 1,123-amino-acid protein of unknown function, while the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85f197a315d6aa34d6d4d2ff6cf4da83
https://doi.org/10.1128/jvi.65.2.769-786.1991
https://doi.org/10.1128/jvi.65.2.769-786.1991
Publikováno v:
Cancer research. 61(17)
It is well established that ErbB1 and ErbB2 can cooperate in mammary epithelial cell transformation. Therefore, to understand how ErbB1/ErbB2 signaling contributes to this process, we used the ErbB kinase inhibitor AG1478in ErbB2-dependent BT-474 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d14603d42d8a37878972650829ef427e
https://pubmed.ncbi.nlm.nih.gov/11522658
https://pubmed.ncbi.nlm.nih.gov/11522658
Autor:
W M, Flanagan
Publikováno v:
Cancer metastasis reviews. 17(2)
During the last ten years, antisense technology has experienced growing pains not unlike those of adolescence. In 1992, antisense was trumpeted as one of the top 10 emerging research areas. However, 3 years later, researchers were confronted with sig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1b025a444722262739f9807e5ed7944a
https://pubmed.ncbi.nlm.nih.gov/9770113
https://pubmed.ncbi.nlm.nih.gov/9770113
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 159(2)
IL-4 is a pleiotrophic cytokine that has been shown to affect cells of the central nervous system. We have demonstrated that IL-4 inhibits DNA synthesis and proliferation in human astroglia expressing IL-4 receptors. In this study, we sought to ident
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2b5e3e4094fbdb6ed2e3c5bc81ff1a47
https://pubmed.ncbi.nlm.nih.gov/9218599
https://pubmed.ncbi.nlm.nih.gov/9218599
Autor:
W M, Flanagan, R W, Wagner
Publikováno v:
Molecular and cellular biochemistry. 172(1-2)
The development of antisense technology as a generally useful tool relies on the use of potent agents and the utilization of many controls in experiments. Here we describe our experience using oligodeoxynucleotides (ODNs) containing C-5 propynyl pyri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::73883bf2df185beb420e8370efe475e5
https://pubmed.ncbi.nlm.nih.gov/9278247
https://pubmed.ncbi.nlm.nih.gov/9278247
Autor:
Avinash Kothavale, R. W. Hendren, Richard W. Wagner, Jason Lewis, Kuei-Ying Lin, W. M. Flanagan, Robert A. Mook, Mark D. Matteucci, R. B. Deprince
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 93(8)
Development of antisense technology has focused in part on creating improved methods for delivering oligodeoxynucleotides (ODNs) to cells. In this report, we describe a cationic lipid that, when formulated with the fusogenic lipid dioleoylphosphatidy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abc67ed86c2ae09caeaa9bd0cf14636b
https://pubmed.ncbi.nlm.nih.gov/8622909
https://pubmed.ncbi.nlm.nih.gov/8622909
Autor:
J, Nourse, E, Firpo, W M, Flanagan, S, Coats, K, Polyak, M H, Lee, J, Massague, G R, Crabtree, J M, Roberts
Publikováno v:
Nature. 372(6506)
The cyclin-dependent kinase (Cdk) enzymes, when associated with the G1 cyclins D and E, are rate-limiting for entry into the S phase of the cell cycle. During T-cell mitogenesis, antigen-receptor signalling promotes synthesis of cyclin E and its cata
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::81f27d1f42019194f26bdc8f5c43ccf5
https://pubmed.ncbi.nlm.nih.gov/7990932
https://pubmed.ncbi.nlm.nih.gov/7990932