Zobrazeno 1 - 10
of 21
pro vyhledávání: '"W M, Kluwe"'
Publikováno v:
Investigational New Drugs. 9:159-168
The pharmacokinetics of 2',3'-dideoxyadenosine (ddAdo) and 2'-3'-dideoxyinosine (ddIno) were determined after intravenous bolus administration and long-term intravenous infusion of ddAdo in dogs. ddAdo was rapidly deaminated to ddIno and ddAdo plasma
Publikováno v:
Toxicological Sciences. 14:40-53
Publikováno v:
Fundamental and Applied Toxicology. 14:40-53
Pyridostigmine bromide, a reversible cholinesterase inhibitor, was administered orally (capsule gavage) to beagle dogs (10–15 months of age) of both sexes once daily at 5, 10, or 20 mg/kg for 14 days; every 8 hr at 2 or 5 mg/kg for 28 days; or ever
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 14(1)
Pyridostigmine bromide, a reversible cholinesterase inhibitor, was administered orally (capsule gavage) to beagle dogs (10-15 months of age) of both sexes once daily at 5, 10, or 20 mg/kg for 14 days; every 8 hr at 2 or 5 mg/kg for 28 days; or every
Publikováno v:
Environmental Health Perspectives
Mice ingesting a standard rodent diet supplemented with polybrominated biphenyls (PBBs) were more susceptible to chlorinated hydrocarbon solvent-induced renal and hepatic damage, as well as the lethal effects of CHCl3 and CCl4, than were mice consumi
Publikováno v:
Journal of Toxicology and Environmental Health. 15:745-767
Acute (single exposure), 14-d repeated exposure, 91-d subchronic, and 103-wk chronic toxicity studies of orally administered (gavage, in corn oil) monochlorobenzene were conducted in male and female Fischer-344 rats and B6C3F1 hybrid mice. A single e
Autor:
J E, Huff, W M, Kluwe
Publikováno v:
Progress in clinical and biological research. 141
Publikováno v:
Journal of toxicology and environmental health. 12(1)
The commonly used plasticizer di(2-ethylhexyl) phthalate (DEHP) was recently tested for chronic toxic potential by incorporation into the diet of rats and mice for approximately 2 yr. Upon reviewing the test results, the sponsoring organization concl
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 205(3)
Fourteen-day-old and adult rabbits received procaine penicillin G (PEN), 450,000 U/kg s.c., every 12 hours for a total of four doses or phenobarbital-Na (PHB), 40 mg/kg i.p., once daily for 3 days, or 3-methylcholanthrene (3MC), to 20 mg/kg i.p., onc
Publikováno v:
Journal of applied toxicology : JAT. 2(5)
The concentration-dependent abilities of SKF 525-A, metyrapone (MET), piperonyl butoxide (PB), allyl-isopropylacetamide (AIA) and alpha-naphthoflavone (7,8-benzoflavone; ANF) to inhibit the activities of p-chloro-N-methylaniline-N-demethylase (PCNMA)