Zobrazeno 1 - 10 of 71 pro vyhledávání: '"W M, Howell"'
1
VEGF polymorphisms and severity of atherosclerosis
Autor: Shu Ye, W M Howell, S Ali, Matthew J. J. Rose-Zerilli
Publikováno v: Journal of Medical Genetics. 42:485-490
Introduction: Vascular endothelial growth factor (VEGF) is a potent angiogenic factor, and neovascularisation has been shown to be important in atherosclerotic plaque development. There is some disagreement as to whether VEGF acts as a pro-atheroscle
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6809cd8250745038181c8ca41a2878c
https://doi.org/10.1136/jmg.2004.025734
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2
Immunomonitoring of Renal Transplant Recipients in the Early Posttransplant Period by Sequential Analysis of Chemokine and Chemokine Receptor Gene Expression in Peripheral Blood Mononuclear Cells
Autor: Sami A. Sadek, P. Pead, J N. Webber, W M. Howell, R S.J. Dalton, P.J. Gibbs
Publikováno v: Transplantation Proceedings. 37:747-751
Introduction We sought to determine whether sequential changes in chemokine ligand/receptor gene expression in the early posttransplant period of human renal allografts can be detected in peripheral blood mononuclear cells (PBMCs) and whether any suc
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f42897c1bac984fa6fa96aa8fdfbab55
https://doi.org/10.1016/j.transproceed.2004.12.097
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3
Cytokine gene single nucleotide polymorphisms and susceptibility to and prognosis in cutaneous malignant melanoma
Autor: J. M. Theaker, S. J. Turner, Adrian C Bateman, W. M. Howell
Publikováno v: European Journal of Immunogenetics. 30:409-414
Cutaneous malignant melanoma (CMM) is a potentially fatal malignancy in which exposure to UV light is the most important risk factor. Several lines of evidence suggest that CMM patients develop an immune response to their tumours, although, in most c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d3cb0c70fe909d48a8e2728fe78d6c67
https://doi.org/10.1111/j.1365-2370.2003.00425.x
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4
Influence of vascular endothelial growth factor single nucleotide polymorphisms on tumour development in cutaneous malignant melanoma
Autor: J. M. Theaker, Andrew Collins, Adrian C Bateman, W. M. Howell, S J Turner
Publikováno v: Genes & Immunity. 3:229-232
Vascular endothelial growth factor (VEGF) is a potent regulator of vasculogenesis and tumour angiogenesis. We have investigated whether the VEGF -2578, -1154, +405 and +936 SNPs and associated haplotypes confer susceptibility to and/or influence prog
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4c1df804e3e6ef2ca2fa40c7f73ea0
https://doi.org/10.1038/sj.gene.6363851
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7
IL-10 promoter polymorphisms influence tumour development in cutaneous malignant melanoma
Autor: S J Turner, W. M. Howell, J. M. Theaker, Adrian C Bateman
Publikováno v: Genes & Immunity. 2:25-31
Cutaneous malignant melanoma (CMM) is the most serious cutaneous malignancy. CMM patients often develop an immune response to their tumours. Conflicting evidence suggests that IL-10 may contribute to tumour escape from the immune response, but may al
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f0202f320bf67fef55c4969431cd9fd7
https://doi.org/10.1038/sj.gene.6363726
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8
British Society for Histocompatibility & Immunogenetics and British Transplantation Society Guidelines for the Detection and Characterisation of Clinically Relevant Antibodies in Allotransplantation
Autor: Craig J. Taylor, P. Sinnott, P. Dyer, Robert Vaughan, John D. Smith, A. Harmer, David Briggs, W. M. Howell, Susan Martin, Susan V. Fuggle
Publikováno v: International Journal of Immunogenetics. 37:435-437
Ongoing technological developments in antibody detection and characterisation allowing relative quantitation of HLA-specific antibody levels, combined with crossmatch results, now allow a graded assessment of patient potential donor immunological ris
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f2ce569575cb1529e9a0fe7db89b7147
https://doi.org/10.1111/j.1744-313x.2010.00955.x
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9
Two novel immortal pancreatic beta-cell lines expressing and secreting human islet amyloid polypeptide do not spontaneously develop islet amyloid
Autor: Thomas N. Wight, Sofianos Andrikopoulos, Jeanette Teague, Steven E. Kahn, Wilfred Y. Fujimoto, C. B. Verchere, W M Howell
Publikováno v: Diabetes. 48:1962-1970
Type 2 diabetes is characterized by islet amyloid deposits, which are primarily composed of the amyloidogenic human form of islet amyloid polypeptide (IAPP, amylin). The mechanism of islet amyloido-genesis is not known, but other products (e.g., apol
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fcf1020a47e00d3cfb287484f9cca4d
https://doi.org/10.2337/diabetes.48.10.1962
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10
HLA class II DRB1, DQB1 and DPB1 genotypic associations with peanut allergy: evidence from a family-based and case-control study
Autor: S J Turner, Jonathan O'b Hourihane, W. M. Howell, Taraneh Dean, Jane Warner
Publikováno v: Clinical & Experimental Allergy. 28:156-162
Background Peanut is one of the most common foods provoking allergic reactions and is the most frequent cause of fatal and near-fatal food-induced anaphylaxis. However, as yet, little is known of the genetic and immunological mechanisms which underly
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d371ce0d259c0b6fa0f85f87192d534a
https://doi.org/10.1046/j.1365-2222.1998.00224.x
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