Výsledky vyhledávání

Augmentation of transvascular transport of macromolecules and nanoparticles in tumors using vascular endothelial growth factor

Autor: W L, Monsky, D, Fukumura, T, Gohongi, M, Ancukiewcz, H A, Weich, V P, Torchilin, F, Yuan, R K, Jain

Publikováno v: Cancer research. 59(16)

The goal of this investigation was to measure changes in vascular permeability, pore cutoff size, and number of transvascular transport pathways as a function of time and in response to vascular endothelial growth factor (VEGF), placenta growth facto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::75344ca926ab710a48965ef877629f67
https://pubmed.ncbi.nlm.nih.gov/10463618

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Mice lacking E-selectin show normal numbers of rolling leukocytes but reduced leukocyte stable arrest on cytokine-activated microvascular endothelium

Autor: D S, Milstone, D, Fukumura, R C, Padgett, P E, O'Donnell, V M, Davis, O J, Benavidez, W L, Monsky, R J, Melder, R K, Jain, M A, Gimbrone

Publikováno v: Microcirculation (New York, N.Y. : 1994). 5(2-3)

Previous work indicated that E-selectin mediates transient interactions between leukocytes and cytokine-activated endothelium in vitro. Here we examine the role of E-selectin in blood leukocyte interactions with microvascular endothelium in vivo.E-se

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::96438c83cb97c32ff0db64897ce4619a
https://pubmed.ncbi.nlm.nih.gov/9789256

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A potential marker protease of invasiveness, seprase, is localized on invadopodia of human malignant melanoma cells

Autor: W L, Monsky, C Y, Lin, A, Aoyama, T, Kelly, S K, Akiyama, S C, Mueller, W T, Chen

Publikováno v: Cancer research. 54(21)

Seprase, a large, gelatin-degrading membrane-protease complex, is expressed at the invasive front of malignant melanoma cells on invadopodia, and its surface expression contributes to the invasive phenotype. An in vitro assay was used to determine th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::56d2318dce50e9e3a3975ca8bbfe039e
https://pubmed.ncbi.nlm.nih.gov/7923219

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Binding and localization of M(r) 72,000 matrix metalloproteinase at cell surface invadopodia

Autor: W L, Monsky, T, Kelly, C Y, Lin, Y, Yeh, W G, Stetler-Stevenson, S C, Mueller, W T, Chen

Publikováno v: Cancer research. 53(13)

Degradation (turnover) of collagenous matrix occurs on the surface of specialized membrane extensions termed "invadopodia," which are sites of cell invasion into the extracellular matrix. Here we show the localization of the M(r) 72,000 type IV colla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::41ac1aac0514616637ef353a156d868f
https://pubmed.ncbi.nlm.nih.gov/8391388

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Protease production by cultured microglia: substrate gel analysis and immobilized matrix degradation

Autor: W. L. Monsky, Jonette Keri, Carol A. Colton, W. T. Chen

Publikováno v: Journal of neuroscience research. 35(3)

The production of collagen-degrading proteases by cultured neonatal rat microglia was examined using an immobilized fibronectin-gelatin matrix coupled to a fluorescent marker and by substrate gel analysis. When microglia were plated onto the surface

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89328fb23a7444bcc312a0c48d0da186
https://pubmed.ncbi.nlm.nih.gov/8350390

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