Zobrazeno 1 - 10
of 263
pro vyhledávání: '"W Joost Wiersinga"'
Autor:
Peter Pickkers, Evangelos J Giamarellos-Bourboulis, Joanna C Dionne, M G Netea, Simon J W Oczkowski, Tom van der Poll, W Joost Wiersinga, Lonneke A van Vught, Alexander P J Vlaar, Marleen A Slim, Niels van Mourik, Marcella C A Müller
Publikováno v:
BMJ Open, Vol 12, Iss 5 (2022)
Introduction Sepsis, a life-threatening organ dysfunction syndrome occurring in the context of severe infections, remains a major burden on global health with high morbidity and high mortality rates. Despite recent advances in the understanding of it
Externí odkaz:
https://doaj.org/article/b4859983a77448a9ace9a11204c5a3bb
Autor:
Alex R Schuurman, Tom DY Reijnders, Anno Saris, Ivan Ramirez Moral, Michiel Schinkel, Justin de Brabander, Christine van Linge, Louis Vermeulen, Brendon P Scicluna, W Joost Wiersinga, Felipe A Vieira Braga, Tom van der Poll
Publikováno v:
eLife, Vol 10 (2021)
The exact immunopathophysiology of community-acquired pneumonia (CAP) caused by SARS-CoV-2 (COVID-19) remains clouded by a general lack of relevant disease controls. The scarcity of single-cell investigations in the broader population of patients wit
Externí odkaz:
https://doaj.org/article/86b1440bbe734205ab4a4e76ebe22bbb
Autor:
Henk A Marquering, Dan Piña-Fuentes, Martijn Beudel, Iwan C C van der Horst, Auke C Reidinga, Roger J M W Rennenberg, Martijn D de Kruif, Marcus L F Janssen, Marcel J H Aries, Suat Simsek, Joop P van den Bergh, Lucas A Ramos, Paul W G Elbers, W Joost Wiersinga, Maarten C Ottenhoff, Wouter Potters, Deborah Hubers, Shi Hu, Egill A Fridgeirsson, Rajat Thomas, Christian Herff, Pieter Kubben, Max Welling, Lucas M Fleuren, Michiel Schinkel, Peter G Noordzij, Caroline E Wyers, David T B Buis, Ella H C van den Hout, Daisy Rusch, Kim C E Sigaloff, Renee A Douma, Lianne de Haan, Niels C Gritters van den Oever, Guido A van Wingen
Publikováno v:
BMJ Open, Vol 11, Iss 7 (2021)
Objective Develop and validate models that predict mortality of patients diagnosed with COVID-19 admitted to the hospital.Design Retrospective cohort study.Setting A multicentre cohort across 10 Dutch hospitals including patients from 27 February to
Externí odkaz:
https://doaj.org/article/48cf1da3917d41a5bb63a26c7d037554
Correction: Increased Von Willebrand factor, decreased ADAMTS13 and thrombocytopenia in melioidosis.
Autor:
Emma Birnie, Gavin C K W Koh, Ester C Löwenberg, Joost C M Meijers, Rapeephan R Maude, Nicholas P J Day, Sharon J Peacock, Tom van der Poll, W Joost Wiersinga
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 9, p e0008722 (2020)
[This corrects the article DOI: 10.1371/journal.pntd.0005468.].
Externí odkaz:
https://doaj.org/article/c22896b715e240bdb05629c7431fe5ad
Autor:
Max C Jacobs, Jacqueline M Lankelma, Nora S Wolff, Floor Hugenholtz, Alex F de Vos, Tom van der Poll, W Joost Wiersinga
Publikováno v:
PLoS ONE, Vol 15, Iss 11, p e0241748 (2020)
BackgroundAn increasing body of evidence is indicating that the gut microbiota modulates pulmonary inflammatory responses. This so-called gut-lung axis might be of importance in a whole spectrum of inflammatory pulmonary diseases such as acute respir
Externí odkaz:
https://doaj.org/article/041958d13b2c4f0caf82b8d21fdaf93a
Autor:
Emma Birnie, Senne van 't Hof, Anne Bijnsdorp, Yembeh Mansaray, Erdi Huizenga, Arie van der Ende, Floor Hugenholtz, Martin P Grobusch, W Joost Wiersinga
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 6, p e0007402 (2019)
BackgroundThe soil-dwelling bacillus Burkholderia pseudomallei is the etiological-agent of the neglected and life-threatening emerging infection melioidosis. The distribution of B. pseudomallei in West Africa is unknown. In the present study we aimed
Externí odkaz:
https://doaj.org/article/75347de683bc4373a54b96d17c8fedcc
Autor:
Direk Limmathurotsakul, Frances Daily, Sotharith Bory, Gaetan Khim, W Joost Wiersinga, Alfredo G Torres, David A B Dance, Bart J Currie
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 3, p e0007123 (2019)
Externí odkaz:
https://doaj.org/article/a1b394a239e04f1dbc90a40653895d61
Autor:
Jacqueline M Lankelma, Emma Birnie, Tassili A F Weehuizen, Brendon P Scicluna, Clara Belzer, Riekelt H Houtkooper, Joris J T H Roelofs, Alex F de Vos, Tom van der Poll, Andries E Budding, W Joost Wiersinga
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 4, p e0005548 (2017)
BACKGROUND:Melioidosis, caused by the Gram-negative bacterium Burkholderia pseudomallei, is an emerging cause of pneumonia-derived sepsis in the tropics. The gut microbiota supports local mucosal immunity and is increasingly recognized as a protectiv
Externí odkaz:
https://doaj.org/article/dbb4275ecc72483c9193e0ce3e72d484
Autor:
Emma Birnie, Gavin C K W Koh, Ester C Löwenberg, Joost C M Meijers, Rapeephan R Maude, Nicholas P J Day, Sharon J Peacock, Tom van der Poll, W Joost Wiersinga
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 3, p e0005468 (2017)
BACKGROUND:Melioidosis, caused by bioterror treat agent Burkholderia pseudomallei, is an important cause of community-acquired Gram-negative sepsis in Southeast Asia and Northern Australia. New insights into the pathogenesis of melioidosis may help i
Externí odkaz:
https://doaj.org/article/6532bcd5ea2d4bd8aab7124f8b6891fa
Autor:
Tassili A F Weehuizen, Tijmen J Hommes, Jacqueline M Lankelma, Hanna K de Jong, Joris J T H Roelofs, Alex F de Vos, Marco Colonna, Tom van der Poll, W Joost Wiersinga
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 6, p e0004747 (2016)
Triggering receptor expressed on myeloid cells (TREM) -1 and TREM-2 are key regulators of the inflammatory response that are involved in the clearance of invading pathogens. Melioidosis, caused by the "Tier 1" biothreat agent Burkholderia pseudomalle
Externí odkaz:
https://doaj.org/article/74a74f66e58140c1a692b7eb260978c9