Zobrazeno 1 - 8
of 8
pro vyhledávání: '"W J Poynor"'
Publikováno v:
Biopharmaceuticsdrug disposition. 19(8)
To determine the effect of reduced hepatic function on the pharmacokinetics of minoxidil. The pharmacokinetics of antipyrine, lorazepam, and indocyanine green were included as indicators of hepatic function.Eight mild cirrhotics and eight healthy sub
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::428b9d08ecc0ef99772cc048671d920c
https://pubmed.ncbi.nlm.nih.gov/9840212
https://pubmed.ncbi.nlm.nih.gov/9840212
Autor:
A C, Rudy, W J, Poynor
Publikováno v:
Pharmaceutical research. 7(10)
A high-performance liquid chromatographic (HPLC) assay was developed for pyrimethamine in plasma, red blood cells (RBCs), and buffer for the purpose of studying its plasma protein binding and RBC partitioning. Pyrimethamine (1000 ng/ml) was 94% bound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ced930ae4ffc71bd49071976e28c242c
https://pubmed.ncbi.nlm.nih.gov/2281036
https://pubmed.ncbi.nlm.nih.gov/2281036
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 8(2)
Saccharin is not metabolized and is rapidly eliminated in urine of the rat. Factors that affect renal excretion, i.e., protein binding, glomerular filtration rate (GFR), and tubular secretion, would thus be important in determining saccharin clearanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::516c34c9664cf0b14870eb3b1766aa5f
https://pubmed.ncbi.nlm.nih.gov/6103789
https://pubmed.ncbi.nlm.nih.gov/6103789
Publikováno v:
Clinical pharmacy. 6(11)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0a27c9bfccac091e79fc62ccfce2aff
https://pubmed.ncbi.nlm.nih.gov/3677567
https://pubmed.ncbi.nlm.nih.gov/3677567
Publikováno v:
Clinical pharmacy. 3(4)
The removal of salicylate by plasma exchange in normal subjects was studied. Six healthy men volunteers were given aspirin 975 mg every six hours for five days before undergoing plasma exchange. Blood samples for determination of serum salicylate con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ba4407fd768361a753dc534f70fd98e3
https://pubmed.ncbi.nlm.nih.gov/6467875
https://pubmed.ncbi.nlm.nih.gov/6467875
Single-dose model for predicting steady-state valproic acid serum concentrations in seizure patients
Publikováno v:
Clinical pharmacy. 3(6)
Valproic acid serum concentrations predicted by a single-dose prediction model were compared with steady-state serum concentrations measured after the start of therapy in seizure patients. Ten patients receiving valproic acid for the first time or wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f169df82e20da144a750659b2bb7743c
https://pubmed.ncbi.nlm.nih.gov/6439455
https://pubmed.ncbi.nlm.nih.gov/6439455
Publikováno v:
Clinical pharmacy. 2(1)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3851b1f2e20b05adfa9a978a29cbd58d
https://pubmed.ncbi.nlm.nih.gov/6411411
https://pubmed.ncbi.nlm.nih.gov/6411411
Publikováno v:
Antimicrobial agents and chemotherapy. 29(1)
The pharmacokinetics and safety of orally administered ciprofloxacin (Bay o 9867) were examined in 12 healthy male volunteers who received sequential doses of 250, 500, 750, and 1,000 mg. The individual and mean data were best described by biexponent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a321070a6b276a7c694228ff19514cb
https://pubmed.ncbi.nlm.nih.gov/2942101
https://pubmed.ncbi.nlm.nih.gov/2942101